메뉴 건너뛰기




Volumn 15, Issue 1, 2009, Pages 20-32

When to treat and the benefits of treating hepatitis C in patients with haemophilia

Author keywords

Antiviral therapy; Cirrhosis; Haemophilia; Hepatic fibrosis; Hepatitis C

Indexed keywords

ALPHA INTERFERON; BLOOD CLOTTING FACTOR CONCENTRATE; ENZYME INHIBITOR; ERYTHROPOIETIN; IMMUNOMODULATING AGENT; INTERFERON; PEGINTERFERON ALPHA; RIBAVIRIN;

EID: 63049086019     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2008.01917.x     Document Type: Review
Times cited : (6)

References (153)
  • 1
    • 0003171299 scopus 로고    scopus 로고
    • Report of WHO consultation organized in collaboration with the Viral Hepatitis Prevention Board, Belgium
    • Global Surveillance and control of hepatitis C
    • Global Surveillance and control of hepatitis C. Report of WHO consultation organized in collaboration with the Viral Hepatitis Prevention Board, Belgium. J Viral Hepatol 1999; 6: 35-47.
    • (1999) J Viral Hepatol , vol.6 , pp. 35-47
  • 2
    • 0037301031 scopus 로고    scopus 로고
    • Appendix: The National Institute of Health Consensus Development Conference Management of Hepatitis C 2002
    • Seef LB, Hoofnagle JH. Appendix: The National Institute of Health Consensus Development Conference Management of Hepatitis C 2002. Clin Liver Dis 2003; 7: 261-87.
    • (2003) Clin Liver Dis , vol.7 , pp. 261-287
    • Seef, L.B.1    Hoofnagle, J.H.2
  • 3
    • 36549017862 scopus 로고    scopus 로고
    • Hospital admission is a relevant source of hepatitis C virus acquisition in Spain
    • Martinez-Bauer E, Forns X, Armelles M et al. Hospital admission is a relevant source of hepatitis C virus acquisition in Spain. J Hepatol 2008; 48: 20-7.
    • (2008) J Hepatol , vol.48 , pp. 20-27
    • Martinez-Bauer, E.1    Forns, X.2    Armelles, M.3
  • 4
    • 0033584440 scopus 로고    scopus 로고
    • The prevalence of hepatitis C virus infection in the United States, 1988 through 1994
    • Alter MJ, Kruszon-Moran D, Nainan OV et al. The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. N Engl J Med 1999; 341: 556-62.
    • (1999) N Engl J Med , vol.341 , pp. 556-562
    • Alter, M.J.1    Kruszon-Moran, D.2    Nainan, O.V.3
  • 6
  • 7
    • 0033665744 scopus 로고    scopus 로고
    • The natural history of HCV in a cohort of hemophilic patients infected between 1961 and 1985
    • Yee TT, Griffioen A, Sabin CA, Dusheiko G, Lee CA. The natural history of HCV in a cohort of hemophilic patients infected between 1961 and 1985. Gut 2000; 47: 845-51.
    • (2000) Gut , vol.47 , pp. 845-851
    • Yee, T.T.1    Griffioen, A.2    Sabin, C.A.3    Dusheiko, G.4    Lee, C.A.5
  • 8
    • 0025268925 scopus 로고
    • Hepatitis C antibody and chronic liver disease in hemophilia
    • Makris M, Preston FE, Triger DR et al. Hepatitis C antibody and chronic liver disease in hemophilia. Lancet 1990; 335: 1117-9.
    • (1990) Lancet , vol.335 , pp. 1117-1119
    • Makris, M.1    Preston, F.E.2    Triger, D.R.3
  • 9
    • 0027387023 scopus 로고
    • A multicenter study of viral hepatitis in a United States hemophilic population
    • Troisi CL, Hollinger FB, Hoots WK et al. A multicenter study of viral hepatitis in a United States hemophilic population. Blood 1993; 81: 412-8.
    • (1993) Blood , vol.81 , pp. 412-418
    • Troisi, C.L.1    Hollinger, F.B.2    Hoots, W.K.3
  • 10
    • 63049101969 scopus 로고    scopus 로고
    • World Federation of Haemophilia
    • World Federation of Haemophilia. 2006 WFH Global Survey, 2006. http://www.wfh.org/index.asp?lang=EN.
    • (2006) 2006 WFH Global Survey
  • 11
    • 33745932260 scopus 로고    scopus 로고
    • Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21years of follow-up
    • Arnold DM, Julian JA, Walker IR, Association of Hemophilia Clinic Directors of Canada. Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21years of follow-up. Blood 2006; 108: 460-4.
    • (2006) Blood , vol.108 , pp. 460-464
    • Arnold, D.M.1    Julian, J.A.2    Walker, I.R.3
  • 14
    • 0028310374 scopus 로고
    • The progression of HCV-associated liver disease in cohort haemophilic patients
    • Telfer P, Sabin C, Devereux H et al. The progression of HCV-associated liver disease in cohort haemophilic patients. Br J Haematol 1994; 87: 555-61.
    • (1994) Br J Haematol , vol.87 , pp. 555-561
    • Telfer, P.1    Sabin, C.2    Devereux, H.3
  • 15
    • 33645998423 scopus 로고    scopus 로고
    • Mortality and causes of death in patients with hemophilia, 1992-2001: A prospective cohort study
    • Plug I, Van Der Bom JG, Peters M et al. Mortality and causes of death in patients with hemophilia, 1992-2001: A prospective cohort study. J Thromb Haemost 2006; 4: 510-6.
    • (2006) J Thromb Haemost , vol.4 , pp. 510-516
    • Plug, I.1    Van Der Bom, J.G.2    Peters, M.3
  • 16
    • 0028905430 scopus 로고
    • Variability of hepatitis C virus
    • Simmonds P. Variability of hepatitis C virus. Hepatology 1995; 21: 570-83.
    • (1995) Hepatology , vol.21 , pp. 570-583
    • Simmonds, P.1
  • 17
    • 0028865091 scopus 로고
    • Chronic hepatitis C virus infection in haemophilic patients: Clinical significance of viral genotype
    • Telfer PT, Devereux H, Savage K et al. Chronic hepatitis C virus infection in haemophilic patients: Clinical significance of viral genotype. Thromb Haemost 1995; 74: 1259-64.
    • (1995) Thromb Haemost , vol.74 , pp. 1259-1264
    • Telfer, P.T.1    Devereux, H.2    Savage, K.3
  • 18
    • 0032212556 scopus 로고    scopus 로고
    • Infection among multitransfused thalassemics from HCV genotypes in Northern Italy: A survey of 1368 histologically proven chronic hepatitis C patients
    • Roffi L, Ricci A, Ogliari C. Infection among multitransfused thalassemics from HCV genotypes in Northern Italy: A survey of 1368 histologically proven chronic hepatitis C patients. J Hepatol 1998; 29: 701-6.
    • (1998) J Hepatol , vol.29 , pp. 701-706
    • Roffi, L.1    Ricci, A.2    Ogliari, C.3
  • 19
    • 33846912807 scopus 로고    scopus 로고
    • Hepatitis C virus genotypes among patients with thalassemia and inherited bleeding disorders in Markazi province, Iran
    • Samimi-Rad K, Shahbaz B. Hepatitis C virus genotypes among patients with thalassemia and inherited bleeding disorders in Markazi province, Iran. Haemophilia 2007; 13: 156-63.
    • (2007) Haemophilia , vol.13 , pp. 156-163
    • Samimi-Rad, K.1    Shahbaz, B.2
  • 20
    • 0033451928 scopus 로고    scopus 로고
    • Hepatitis C virus infection in Western Europe
    • Trepo C, Pradat P. Hepatitis C virus infection in Western Europe. J Hepatol 1999; 31: 80-3.
    • (1999) J Hepatol , vol.31 , pp. 80-83
    • Trepo, C.1    Pradat, P.2
  • 21
    • 0033404626 scopus 로고    scopus 로고
    • Clinical significance of hepatitis C virus genotypes
    • Mondelli MU, Silini E. Clinical significance of hepatitis C virus genotypes. J Hepatol 1999; 31: 65-70.
    • (1999) J Hepatol , vol.31 , pp. 65-70
    • Mondelli, M.U.1    Silini, E.2
  • 22
    • 0037222767 scopus 로고    scopus 로고
    • Spontaneous viral clearance in patients with acute hepatitis C can be predicted by repeated measurements of serum viral load
    • Hofer H, Watkins-Riedel T, Janata O et al. Spontaneous viral clearance in patients with acute hepatitis C can be predicted by repeated measurements of serum viral load. Hepatology 2003; 37: 60-4.
    • (2003) Hepatology , vol.37 , pp. 60-64
    • Hofer, H.1    Watkins-Riedel, T.2    Janata, O.3
  • 23
    • 0038575483 scopus 로고    scopus 로고
    • Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
    • Gerlach JT, Diepolder HM, Zachoval R et al. Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance. Gastroenterology 2003; 125: 80-8.
    • (2003) Gastroenterology , vol.125 , pp. 80-88
    • Gerlach, J.T.1    Diepolder, H.M.2    Zachoval, R.3
  • 24
    • 0036829816 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis C
    • Seeff LB. Natural history of chronic hepatitis C. Hepatology 2002; 36: S35-46.
    • (2002) Hepatology , vol.36
    • Seeff, L.B.1
  • 25
    • 0027068086 scopus 로고
    • The natural history of community-acquired hepatitis C in the United States
    • Alter MJ, Margolis HS, Krawczynski K et al. The natural history of community-acquired hepatitis C in the United States. N Engl J Med 1992; 327: 1899-905.
    • (1992) N Engl J Med , vol.327 , pp. 1899-1905
    • Alter, M.J.1    Margolis, H.S.2    Krawczynski, K.3
  • 26
    • 0033594380 scopus 로고    scopus 로고
    • Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin
    • for the Irish Hepatology Research Group
    • Kenny-Walsh E, for the Irish Hepatology Research Group. Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. N Eng J Med 1999; 340: 1228-33.
    • (1999) N Eng J Med , vol.340 , pp. 1228-1233
    • Kenny-Walsh, E.1
  • 27
    • 0033576001 scopus 로고    scopus 로고
    • Prevalence and clinical outcome of hepatitis C infection in children who underwent cardiac surgery before the implementation of blood-donor screening
    • Vogt M, Lay T, Frosner G et al. Prevalence and clinical outcome of hepatitis C infection in children who underwent cardiac surgery before the implementation of blood-donor screening. N Engl J Med 1999; 341: 866-70.
    • (1999) N Engl J Med , vol.341 , pp. 866-870
    • Vogt, M.1    Lay, T.2    Frosner, G.3
  • 28
    • 0034235962 scopus 로고    scopus 로고
    • Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in Germany: A 20-year multicenter study
    • Wiese M, Berr F, Lafrenz M, Porst H, Olsen V. Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in Germany: A 20-year multicenter study. Hepatology 2000; 32: 91-6.
    • (2000) Hepatology , vol.32 , pp. 91-96
    • Wiese, M.1    Berr, F.2    Lafrenz, M.3    Porst, H.4    Olsen, V.5
  • 29
    • 17744395299 scopus 로고    scopus 로고
    • Long-term mortality and morbidity of transfusion-associated non-A, non-B and type C hepatitis; a National Heart, Lung and Blood Institute collaborative study
    • Seeff LB, Hollinger FB, Alter HJ et al. Long-term mortality and morbidity of transfusion-associated non-A, non-B and type C hepatitis; a National Heart, Lung and Blood Institute collaborative study. Hepatology 2001; 33: 455-63.
    • (2001) Hepatology , vol.33 , pp. 455-463
    • Seeff, L.B.1    Hollinger, F.B.2    Alter, H.J.3
  • 30
    • 0025037547 scopus 로고
    • Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus
    • Kiyosawa K, Sodeyama T, Tanaka E et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990; 12: 671-5.
    • (1990) Hepatology , vol.12 , pp. 671-675
    • Kiyosawa, K.1    Sodeyama, T.2    Tanaka, E.3
  • 31
    • 33744779670 scopus 로고    scopus 로고
    • Hepatitis C in 6,865 patients 65yr or older: A severe and neglected curable disease?
    • Thabut D, Le Calvez S, Thibault V et al. Hepatitis C in 6,865 patients 65yr or older: A severe and neglected curable disease? Am J Gastroenterol 2006; 101: 1260-7.
    • (2006) Am J Gastroenterol , vol.101 , pp. 1260-1267
    • Thabut, D.1    Le Calvez, S.2    Thibault, V.3
  • 32
    • 1942467895 scopus 로고    scopus 로고
    • Normal serum aminotransferase concentration and risk of mortality from liver diseases: Prospective cohort study
    • Kim HC, Nam CM, Jee SH, Han KH, Oh DK, Suh I. Normal serum aminotransferase concentration and risk of mortality from liver diseases: Prospective cohort study. BMJ. 2004; 328: 983.
    • (2004) BMJ , vol.328 , pp. 983
    • Kim, H.C.1    Nam, C.M.2    Jee, S.H.3    Han, K.H.4    Oh, D.K.5    Suh, I.6
  • 33
    • 33646121757 scopus 로고    scopus 로고
    • Chronic hepatitis C in patients with persistently normal alanine transaminase levels
    • Shiffman ML, Diago M, Tran A et al. Chronic hepatitis C in patients with persistently normal alanine transaminase levels. Clin Gastroenterol Hepatol 2006; 4: 645-52.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 645-652
    • Shiffman, M.L.1    Diago, M.2    Tran, A.3
  • 34
    • 0031041924 scopus 로고    scopus 로고
    • Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients
    • Fattovich G, Giustina G, Degos F et al. Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients. Gastroenterology 1997; 112: 463-72.
    • (1997) Gastroenterology , vol.112 , pp. 463-472
    • Fattovich, G.1    Giustina, G.2    Degos, F.3
  • 35
    • 38049125477 scopus 로고    scopus 로고
    • Meta-analyses of FibroTest diagnostic value in chronic liver disease
    • Poynard T, Morra R, Halfon P et al. Meta-analyses of FibroTest diagnostic value in chronic liver disease. BMC Gastroenterol 2007; 7: 40.
    • (2007) BMC Gastroenterol , vol.7 , pp. 40
    • Poynard, T.1    Morra, R.2    Halfon, P.3
  • 36
    • 33947360829 scopus 로고    scopus 로고
    • Sustained virological response to interferon-alpha is associated with improved outcome in HCV-related cirrhosis: A retrospective study
    • Bruno S, Stroffolini T, Colombo M et al. Sustained virological response to interferon-alpha is associated with improved outcome in HCV-related cirrhosis: A retrospective study. Hepatology 2007; 45: 579-87.
    • (2007) Hepatology , vol.45 , pp. 579-587
    • Bruno, S.1    Stroffolini, T.2    Colombo, M.3
  • 37
    • 38449091418 scopus 로고    scopus 로고
    • Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced fibrosis
    • Veldt BJ, Heathcote EJ, Wedemeyer H et al. Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced fibrosis. Ann Intern Med 2007; 147: 677-84.
    • (2007) Ann Intern Med , vol.147 , pp. 677-684
    • Veldt, B.J.1    Heathcote, E.J.2    Wedemeyer, H.3
  • 38
    • 0031927737 scopus 로고    scopus 로고
    • Clinical outcome of hepatitis C as a function of mode of transmission
    • Gordon SC, Bayati N, Silverman AL. Clinical outcome of hepatitis C as a function of mode of transmission. Hepatol 1998; 28: 562-7.
    • (1998) Hepatol , vol.28 , pp. 562-567
    • Gordon, S.C.1    Bayati, N.2    Silverman, A.L.3
  • 39
    • 42949138790 scopus 로고    scopus 로고
    • Disease progression in chronic hepatitis C: Modifiable and nonmodifiable factors
    • Missiha SB, Ostrowski M, Heathcote EJ. Disease progression in chronic hepatitis C: Modifiable and nonmodifiable factors. Gastroenterology. 2008; 134: 1699-714.
    • (2008) Gastroenterology , vol.134 , pp. 1699-1714
    • Missiha, S.B.1    Ostrowski, M.2    Heathcote, E.J.3
  • 40
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C
    • The OBSVIRC, METAVIR, CLINIVIR and DOSVIRC groups
    • The OBSVIRC, METAVIR, CLINIVIR and DOSVIRC groups, Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997; 349: 825-32.
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 41
    • 0035009810 scopus 로고    scopus 로고
    • Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C
    • Poynard T, Ratziu V, Charlotte F, Goodman Z, McHutchison J, Albrecht J. Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C. J Hepatol 2001; 34: 730-9.
    • (2001) J Hepatol , vol.34 , pp. 730-739
    • Poynard, T.1    Ratziu, V.2    Charlotte, F.3    Goodman, Z.4    McHutchison, J.5    Albrecht, J.6
  • 42
    • 30144431739 scopus 로고    scopus 로고
    • Natural history and predictors of disease severity in chronic hepatitis C
    • Massard J, Ratziu V, Thabut D et al. Natural history and predictors of disease severity in chronic hepatitis C. J Hepatol 2006; 44: S19-24.
    • (2006) J Hepatol , vol.44
    • Massard, J.1    Ratziu, V.2    Thabut, D.3
  • 43
    • 17344370538 scopus 로고    scopus 로고
    • Prognosis of chronic hepatitis C: Results of a large, prospective cohort study
    • Niederau C, Lange S, Heintges T et al. Prognosis of chronic hepatitis C: results of a large, prospective cohort study. Hepatology 1998; 28: 1687-95.
    • (1998) Hepatology , vol.28 , pp. 1687-1695
    • Niederau, C.1    Lange, S.2    Heintges, T.3
  • 44
    • 0036902302 scopus 로고    scopus 로고
    • Quantification of fibrosis progression in patients with chronic hepatitis C using a Markov model
    • Deuffic-Burban S, Poynard T, Vallron AJ. Quantification of fibrosis progression in patients with chronic hepatitis C using a Markov model. J Viral Hepat 2002; 9: 114-22.
    • (2002) J Viral Hepat , vol.9 , pp. 114-122
    • Deuffic-Burban, S.1    Poynard, T.2    Vallron, A.J.3
  • 45
    • 35848938907 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and sex
    • Wand J. Hepatocellular carcinoma and sex. N Engl J Med 2007; 357: 1974-6.
    • (2007) N Engl J Med , vol.357 , pp. 1974-1976
    • Wand, J.1
  • 46
    • 0032841858 scopus 로고    scopus 로고
    • Racial differences in responses to therapy with interferon in chronic hepatitis C
    • Consensus Interferon Study Group
    • Reddy KR, Hoofnagle JH, Tong MJ et al. Racial differences in responses to therapy with interferon in chronic hepatitis C. Consensus Interferon Study Group. Hepatology 1999; 30: 787-93.
    • (1999) Hepatology , vol.30 , pp. 787-793
    • Reddy, K.R.1    Hoofnagle, J.H.2    Tong, M.J.3
  • 47
    • 2442665224 scopus 로고    scopus 로고
    • Peg-interferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites
    • Atlantic Coast Hepatitis Treatment Group
    • Muir AJ, Bornstein JD, Killenberg PG, Atlantic Coast Hepatitis Treatment Group. Peg-interferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites. N Engl J Med 2004; 350: 2265-71.
    • (2004) N Engl J Med , vol.350 , pp. 2265-2271
    • Muir, A.J.1    Bornstein, J.D.2    Killenberg, P.G.3
  • 48
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999; 340: 745-50.
    • (1999) N Engl J Med , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 49
    • 0036129997 scopus 로고    scopus 로고
    • Hepatitis C infection in African Americans: Its natural history and histological progression
    • Wiley TE, Brown J, Chan J. Hepatitis C infection in African Americans: its natural history and histological progression. Am J Gastroenterol 2002; 97: 700-6.
    • (2002) Am J Gastroenterol , vol.97 , pp. 700-706
    • Wiley, T.E.1    Brown, J.2    Chan, J.3
  • 50
    • 33947401941 scopus 로고    scopus 로고
    • Impact of aboriginal ethnicity on HCV core-induced IL-10 synthesis: Interaction with IL-10 gene polymorphisms
    • Aborsangaya KB, Dembinski I, Khatkar S, Alphonse MP, Nickerson P, Rempel JD. Impact of aboriginal ethnicity on HCV core-induced IL-10 synthesis: interaction with IL-10 gene polymorphisms. Hepatology 2007; 45: 623-30.
    • (2007) Hepatology , vol.45 , pp. 623-630
    • Aborsangaya, K.B.1    Dembinski, I.2    Khatkar, S.3    Alphonse, M.P.4    Nickerson, P.5    Rempel, J.D.6
  • 51
    • 0031721879 scopus 로고    scopus 로고
    • Impact of alcohol on the histological and clinical progression of hepatitis C infection
    • Wiley TE, McCarthy M, Breidi L, McCarthy M, Layden TJ. Impact of alcohol on the histological and clinical progression of hepatitis C infection. Hepatology 1998; 28: 805-9.
    • (1998) Hepatology , vol.28 , pp. 805-809
    • Wiley, T.E.1    McCarthy, M.2    Breidi, L.3    McCarthy, M.4    Layden, T.J.5
  • 52
    • 0031749109 scopus 로고    scopus 로고
    • Role of alcohol in the progression of liver disease caused by hepatitis C virus infection
    • Ostapowicz G, Watson KJ, Locarnini SA, Desmond PV. Role of alcohol in the progression of liver disease caused by hepatitis C virus infection. Hepatology 1998; 27: 1730-5.
    • (1998) Hepatology , vol.27 , pp. 1730-1735
    • Ostapowicz, G.1    Watson, K.J.2    Locarnini, S.A.3    Desmond, P.V.4
  • 53
    • 27644500797 scopus 로고    scopus 로고
    • Influence of alcohol on the progression of hepatitis C virus infection: A meta-analysis
    • Hutchinson SJ, Bird SM, Goldberg DJ. Influence of alcohol on the progression of hepatitis C virus infection: A meta-analysis. Clin Gastroenterol Hepatol 2005; 3: 1150-9.
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 1150-1159
    • Hutchinson, S.J.1    Bird, S.M.2    Goldberg, D.J.3
  • 54
    • 0037083159 scopus 로고    scopus 로고
    • Alcohol and hepatocellular carcinoma: The effect of lifetime intake and hepatitis virus infections in men and women
    • Donato F, Tagger A, Gelatti U et al. Alcohol and hepatocellular carcinoma: The effect of lifetime intake and hepatitis virus infections in men and women. Am J Epidemiol 2002; 155: 323-31.
    • (2002) Am J Epidemiol , vol.155 , pp. 323-331
    • Donato, F.1    Tagger, A.2    Gelatti, U.3
  • 55
    • 1542724807 scopus 로고    scopus 로고
    • Risks of a range of alcohol intake on hepatitis C related fibrosis
    • Monto A, Patel K, Bostrom A et al. Risks of a range of alcohol intake on hepatitis C related fibrosis. Hepatology 2008; 39: 826-34.
    • (2008) Hepatology , vol.39 , pp. 826-834
    • Monto, A.1    Patel, K.2    Bostrom, A.3
  • 56
    • 0035098941 scopus 로고    scopus 로고
    • Hepatic steatosis in chronic hepatitis C virus infection: Prevalence and clinical correlation
    • Hwang SJ, Luo JC, Chu CW et al. Hepatic steatosis in chronic hepatitis C virus infection: Prevalence and clinical correlation. J Gastroenterol Hepatol 2001; 16: 190-5.
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 190-195
    • Hwang, S.J.1    Luo, J.C.2    Chu, C.W.3
  • 57
    • 0034987263 scopus 로고    scopus 로고
    • Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity
    • Adinolfi LE, Gambardella M, Andreana A, Tripodi MF, Utili R, Ruggiero G. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 2001; 33: 1358-64.
    • (2001) Hepatology , vol.33 , pp. 1358-1364
    • Adinolfi, L.E.1    Gambardella, M.2    Andreana, A.3    Tripodi, M.F.4    Utili, R.5    Ruggiero, G.6
  • 58
    • 0036830436 scopus 로고    scopus 로고
    • Hepatitis C virus genotype 3 is cytopathic to hepatocytes: Reversal of hepatic steatosis after sustained therapeutic response
    • Kumar D, Farrell GC, Fung C, George J. Hepatitis C virus genotype 3 is cytopathic to hepatocytes: Reversal of hepatic steatosis after sustained therapeutic response. Hepatology 2002; 36: 1266-72.
    • (2002) Hepatology , vol.36 , pp. 1266-1272
    • Kumar, D.1    Farrell, G.C.2    Fung, C.3    George, J.4
  • 59
    • 10744224920 scopus 로고    scopus 로고
    • Steatosis affects chronic hepatitis C progression in a genotype-specific way
    • Rubbia-Brandt L, Fabris P, Paganin S et al. Steatosis affects chronic hepatitis C progression in a genotype-specific way. Gut 2004; 53: 406-12.
    • (2004) Gut , vol.53 , pp. 406-412
    • Rubbia-Brandt, L.1    Fabris, P.2    Paganin, S.3
  • 60
    • 33745827799 scopus 로고    scopus 로고
    • Steatosis in chronic hepatitis C: Relationship to the virus and host risk factors
    • Matos CA, Perez CM, Pacheco MS et al. Steatosis in chronic hepatitis C: relationship to the virus and host risk factors. J Gastroenterol Hepatol 2006; 21: 1236-9.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 1236-1239
    • Matos, C.A.1    Perez, C.M.2    Pacheco, M.S.3
  • 62
    • 0037301686 scopus 로고    scopus 로고
    • Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies
    • Castéra L, Hézode C, Roudot-Thoraval F et al. Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies. Gut 2003; 52: 288-92.
    • (2003) Gut , vol.52 , pp. 288-292
    • Castéra, L.1    Hézode, C.2    Roudot-Thoraval, F.3
  • 63
    • 0038122773 scopus 로고    scopus 로고
    • Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C
    • Poynard T, Ratziu V, McHutchison J et al. Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C. Hepatology 2003; 38: 75-85.
    • (2003) Hepatology , vol.38 , pp. 75-85
    • Poynard, T.1    Ratziu, V.2    McHutchison, J.3
  • 64
    • 10744227418 scopus 로고    scopus 로고
    • The impact of steatosis on disease progression and early sustained treatment response in chronic hepatitis C patients
    • Patton HM, Patel K, Behling C et al. The impact of steatosis on disease progression and early sustained treatment response in chronic hepatitis C patients. J Hepatol 2004; 40: 484-90.
    • (2004) J Hepatol , vol.40 , pp. 484-490
    • Patton, H.M.1    Patel, K.2    Behling, C.3
  • 65
    • 0037714524 scopus 로고    scopus 로고
    • Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection
    • Ohata K, Hamasaki K, Toriyama K et al. Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection. Cancer 2003; 97: 3036-43.
    • (2003) Cancer , vol.97 , pp. 3036-3043
    • Ohata, K.1    Hamasaki, K.2    Toriyama, K.3
  • 66
    • 0348134685 scopus 로고    scopus 로고
    • Fibrogenic impact of high serum glucose in chronic hepatitis C
    • LIDO Study Group
    • Ratziu V, Munteanu M, Charlotte F, Bonyhay L, Poynard T, LIDO Study Group. Fibrogenic impact of high serum glucose in chronic hepatitis C. J Hepatol 2003; 39: 1049-55.
    • (2003) J Hepatol , vol.39 , pp. 1049-1055
    • Ratziu, V.1    Munteanu, M.2    Charlotte, F.3    Bonyhay, L.4    Poynard, T.5
  • 67
    • 19944392872 scopus 로고    scopus 로고
    • Insulin resistance is associated with liver fibrosis in non-diabetic chronic hepatitis C patients
    • Muzzi A, Leandro G, Rubbia-Brandt L et al. Insulin resistance is associated with liver fibrosis in non-diabetic chronic hepatitis C patients. J Hepatol 2005; 42: 41-6.
    • (2005) J Hepatol , vol.42 , pp. 41-46
    • Muzzi, A.1    Leandro, G.2    Rubbia-Brandt, L.3
  • 68
    • 15744381704 scopus 로고    scopus 로고
    • Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
    • Romero-Gómez M, Del Mar Viloria M, Andrade RJ et al. Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 2005; 128: 636-41.
    • (2005) Gastroenterology , vol.128 , pp. 636-641
    • Romero-Gómez, M.1    Del Mar Viloria, M.2    Andrade, R.J.3
  • 69
    • 0033779703 scopus 로고    scopus 로고
    • Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States
    • Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med 2000; 133: 592-9.
    • (2000) Ann Intern Med , vol.133 , pp. 592-599
    • Mehta, S.H.1    Brancati, F.L.2    Sulkowski, M.S.3    Strathdee, S.A.4    Szklo, M.5    Thomas, D.L.6
  • 70
    • 46249129186 scopus 로고    scopus 로고
    • Increased risk of hepatocellular carcinoma among patients with hepatitis C cirrhosis and diabetes mellitus
    • Veldt BJ, Chen W, Heathcote EJ et al. Increased risk of hepatocellular carcinoma among patients with hepatitis C cirrhosis and diabetes mellitus. Hepatology 2008; 47: 1856-62.
    • (2008) Hepatology , vol.47 , pp. 1856-1862
    • Veldt, B.J.1    Chen, W.2    Heathcote, E.J.3
  • 71
    • 0345655291 scopus 로고    scopus 로고
    • Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression
    • Hui JM, Sud A, Farrell GC et al. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression. Gastroenterology 2003; 125: 1695-704.
    • (2003) Gastroenterology , vol.125 , pp. 1695-16704
    • Hui, J.M.1    Sud, A.2    Farrell, G.C.3
  • 72
    • 1242340436 scopus 로고    scopus 로고
    • Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life
    • Hickman IJ, Jonsson JR, Prins JB et al. Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life. Gut 2004; 53: 413-9.
    • (2004) Gut , vol.53 , pp. 413-419
    • Hickman, I.J.1    Jonsson, J.R.2    Prins, J.B.3
  • 73
    • 0032837102 scopus 로고    scopus 로고
    • Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus co-infected patients. The multivirc group
    • Benhamou Y, Bochet M, Di Martino V et al. Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus co-infected patients. The multivirc group. Hepatology 1999; 30: 1054-8.
    • (1999) Hepatology , vol.30 , pp. 1054-1058
    • Benhamou, Y.1    Bochet, M.2    Di Martino, V.3
  • 74
    • 0036721470 scopus 로고    scopus 로고
    • End-stage liver disease in persons with hemophilia and transfusion-associated infections
    • Goedert JJ, Eyster ME, Lederman MM et al. End-stage liver disease in persons with hemophilia and transfusion-associated infections. Blood 2002; 100: 1584-9.
    • (2002) Blood , vol.100 , pp. 1584-1589
    • Goedert, J.J.1    Eyster, M.E.2    Lederman, M.M.3
  • 75
    • 0031583763 scopus 로고    scopus 로고
    • Mortality from liver cancer and liver disease in haemophilic men and boys in UK given blood products contaminated with hepatitis C. UK Haemophilia Centre Directors' Organisation
    • Darby SC, Ewart DW, Giangrande PL et al. Mortality from liver cancer and liver disease in haemophilic men and boys in UK given blood products contaminated with hepatitis C. UK Haemophilia Centre Directors'Organisation. Lancet 1997; 350: 1425-31.
    • (1997) Lancet , vol.350 , pp. 1425-1431
    • Darby, S.C.1    Ewart, D.W.2    Giangrande, P.L.3
  • 76
    • 0027156520 scopus 로고
    • Natural history of hepatitis C virus infection in multitransfused hemophiliacs: Effect of coinfection with human immunodeficiency virus
    • The Multicenter Hemophilia Cohort Study
    • Eyster ME, Diamondstone LS, Lien JM, Ehmann WC, Quan S, Goedert JJ. Natural history of hepatitis C virus infection in multitransfused hemophiliacs: Effect of coinfection with human immunodeficiency virus. The Multicenter Hemophilia Cohort Study. J Acquir Immune Defic Syndr 1993; 6: 602-10.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 602-610
    • Eyster, M.E.1    Diamondstone, L.S.2    Lien, J.M.3    Ehmann, W.C.4    Quan, S.5    Goedert, J.J.6
  • 77
    • 34548709023 scopus 로고    scopus 로고
    • Clinical progression of hepatitis C virus-related chronic liver disease in human immunodeficiency virus-infected patients undergoing highly active antiretroviral therapy
    • Pineda JA, García-García JA, Aguilar-Guisado M et al. Clinical progression of hepatitis C virus-related chronic liver disease in human immunodeficiency virus-infected patients undergoing highly active antiretroviral therapy. Hepatology 2007; 46: 622-30.
    • (2007) Hepatology , vol.46 , pp. 622-630
    • Pineda, J.A.1    García-García, J.A.2    Aguilar-Guisado, M.3
  • 78
    • 0344120830 scopus 로고    scopus 로고
    • Effect of antiretroviral therapy on liver-related mortality in patients with HIV and hepatitis C virus coinfection
    • Qurishi N, Kreuzberg C, Lüchters G et al. Effect of antiretroviral therapy on liver-related mortality in patients with HIV and hepatitis C virus coinfection. Lancet 2003; 362: 1708-12.
    • (2003) Lancet , vol.362 , pp. 1708-1712
    • Qurishi, N.1    Kreuzberg, C.2    Lüchters, G.3
  • 79
    • 14944383273 scopus 로고    scopus 로고
    • Clinical outcomes of HIV-HCV co-infection in a large cohort of hemophiliac patients
    • Lichterfeld M, Schmeisser N, Qurishi N et al. Clinical outcomes of HIV-HCV co-infection in a large cohort of hemophiliac patients. J Infect 2005; 50: 221-8.
    • (2005) J Infect , vol.50 , pp. 221-228
    • Lichterfeld, M.1    Schmeisser, N.2    Qurishi, N.3
  • 80
    • 19244377701 scopus 로고    scopus 로고
    • Characteristics of patients with dual infection by hepatitis B and C viruses
    • Zarski JP, Bohn B, Bastie A et al. Characteristics of patients with dual infection by hepatitis B and C viruses. J Hepatol 1998; 28: 27-33.
    • (1998) J Hepatol , vol.28 , pp. 27-33
    • Zarski, J.P.1    Bohn, B.2    Bastie, A.3
  • 81
    • 0033562669 scopus 로고    scopus 로고
    • Rate of incidence of hepatocellular carcinoma in patients with compensated viral cirrhosis
    • Chiaramonte M, Stroffolini T, Vian A et al. Rate of incidence of hepatocellular carcinoma in patients with compensated viral cirrhosis. Cancer 1999; 85: 2132-7.
    • (1999) Cancer , vol.85 , pp. 2132-2137
    • Chiaramonte, M.1    Stroffolini, T.2    Vian, A.3
  • 83
    • 84984583431 scopus 로고    scopus 로고
    • Occult hepatitis B virus infection and clinical outcomes of patients with chronic hepatitis C
    • Kao JH, Chen PJ, Lai MY, Chen DS. Occult hepatitis B virus infection and clinical outcomes of patients with chronic hepatitis C. J Clin Microbiol 2002; 40: 4068-71.
    • (2002) J Clin Microbiol , vol.40 , pp. 4068-4071
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 84
    • 0037215502 scopus 로고    scopus 로고
    • Impact of smoking on histological liver lesions in chronic hepatitis C
    • Hézode C, Lonjon I, Roudot-Thoraval F et al. Impact of smoking on histological liver lesions in chronic hepatitis C. Gut 2003; 52: 126-9.
    • (2003) Gut , vol.52 , pp. 126-129
    • Hézode, C.1    Lonjon, I.2    Roudot-Thoraval, F.3
  • 85
    • 4644276636 scopus 로고    scopus 로고
    • Impact of cigarette smoking on response to interferon therapy in chronic hepatitis C Egyptian patients
    • El-Zayadi A, Selim O, Hamdy H et al. Impact of cigarette smoking on response to interferon therapy in chronic hepatitis C Egyptian patients. World J Gastroenterol 2004; 10: 2963-6.
    • (2004) World J Gastroenterol , vol.10 , pp. 2963-2966
    • El-Zayadi, A.1    Selim, O.2    Hamdy, H.3
  • 86
    • 21344472982 scopus 로고    scopus 로고
    • Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C
    • Hézode C, Roudot-Thoraval F, Nguyen S et al. Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C. Hepatology 2005; 42: 63-71.
    • (2005) Hepatology , vol.42 , pp. 63-71
    • Hézode, C.1    Roudot-Thoraval, F.2    Nguyen, S.3
  • 87
    • 1842479859 scopus 로고    scopus 로고
    • American Association for the Study of Liver Diseases practice guideline: Diagnosis, management, and treatment of hepatitis C
    • Strader DB, Wright T, Thomas DL, Seeff LB. American Association for the Study of Liver Diseases practice guideline: Diagnosis, management, and treatment of hepatitis C. Hepatology 2004; 39: 1147-71.
    • (2004) Hepatology , vol.39 , pp. 1147-1171
    • Strader, D.B.1    Wright, T.2    Thomas, D.L.3    Seeff, L.B.4
  • 88
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison JG, Gordon SC et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial. Lancet 2001; 358: 958-65.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 89
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347: 975-82.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 90
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette H Jr, Morgan TR et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140: 346-55.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette, H.2    Morgan, T.R.3
  • 91
    • 0036784356 scopus 로고    scopus 로고
    • Prognostic factors and early predictability of sustained viral response with peginterferon alpha-2a (40KD)
    • Lee SS, Heathcote EJ, Reddy KR et al. Prognostic factors and early predictability of sustained viral response with peginterferon alpha-2a (40KD). J Hepatol 2002; 37: 500-6.
    • (2002) J Hepatol , vol.37 , pp. 500-506
    • Lee, S.S.1    Heathcote, E.J.2    Reddy, K.R.3
  • 92
    • 46249114151 scopus 로고    scopus 로고
    • Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: A randomized trial
    • Yu ML, Dai CY, Huang JF et al. Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: A randomized trial. Hepatology 2008; 47: 1884-93.
    • (2008) Hepatology , vol.47 , pp. 1884-1893
    • Yu, M.L.1    Dai, C.Y.2    Huang, J.F.3
  • 93
    • 2442683905 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3
    • Zeuzem S, Hultcrantz R, Bourliere M et al. Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3. J Hepatol 2004; 40: 993-9.
    • (2004) J Hepatol , vol.40 , pp. 993-999
    • Zeuzem, S.1    Hultcrantz, R.2    Bourliere, M.3
  • 94
    • 34447318385 scopus 로고    scopus 로고
    • Peginterferon Alfa-2a (40KD) Plus Ribavarin for 16 or 24 Wks in Patients with HCV Genotype 2/3 Infection and Advanced Fibrosis/Cirrhosis
    • Shiffman ML, Suter F, Bacon BR et al. Peginterferon Alfa-2a (40KD) Plus Ribavarin for 16 or 24 Wks in Patients with HCV Genotype 2/3 Infection and Advanced Fibrosis/Cirrhosis. N Engl J Med 2007; 357: 124-34.
    • (2007) N Engl J Med , vol.357 , pp. 124-134
    • Shiffman, M.L.1    Suter, F.2    Bacon, B.R.3
  • 95
    • 10644264391 scopus 로고    scopus 로고
    • Treatment with pegylated interferon and ribavarin in HCVinfection with genotype 2 or 3 for 14 weeks: A pilot study
    • Dalgard O, Bjoro K, Hellum KB et al. Treatment with pegylated interferon and ribavarin in HCVinfection with genotype 2 or 3 for 14 weeks: A pilot study. Hepatology 2004; 40: 1260-5.
    • (2004) Hepatology , vol.40 , pp. 1260-1265
    • Dalgard, O.1    Bjoro, K.2    Hellum, K.B.3
  • 96
    • 36949040347 scopus 로고    scopus 로고
    • Exploring differences in response to treatment with peginterferon alpha 2a (40kD) and ribavirin in chronic hepatitis C between genotypes 2 and 3
    • Powis J, Peltekian KM, Lee SS et al. Exploring differences in response to treatment with peginterferon alpha 2a (40kD) and ribavirin in chronic hepatitis C between genotypes 2 and 3. J Viral Hepat 2008; 15: 52-7.
    • (2008) J Viral Hepat , vol.15 , pp. 52-57
    • Powis, J.1    Peltekian, K.M.2    Lee, S.S.3
  • 97
    • 34548319085 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C virus genotype 1 with peginterferon, ribavirin, and epoetin alpha
    • Shiffman ML, Salvatore J, Hubbard S et al. Treatment of chronic hepatitis C virus genotype 1 with peginterferon, ribavirin, and epoetin alpha. Hepatology 2007; 46: 371-9.
    • (2007) Hepatology , vol.46 , pp. 371-379
    • Shiffman, M.L.1    Salvatore, J.2    Hubbard, S.3
  • 98
    • 0041822106 scopus 로고    scopus 로고
    • Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C
    • Davis GL, Wong JB, McHutchison JG, Manns MP, Harvey J, Albrecht J. Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C. Hepatology 2003; 38: 645-52.
    • (2003) Hepatology , vol.38 , pp. 645-652
    • Davis, G.L.1    Wong, J.B.2    McHutchison, J.G.3    Manns, M.P.4    Harvey, J.5    Albrecht, J.6
  • 99
    • 50649099151 scopus 로고    scopus 로고
    • Rapid virological response is a more important predictor of sustained virological response (SVR) than genotype in patients with chronic hepatitis c virus infection
    • Abstract 7
    • Fried MW, Hadziyannis SJ, Shiffman M, Messinger D, Zeuzem S. Rapid virological response is a more important predictor of sustained virological response (SVR) than genotype in patients with chronic hepatitis c virus infection. Abstract 7, J Hepatol 2008; 48: S5.
    • (2008) J Hepatol , vol.48
    • Fried, M.W.1    Hadziyannis, S.J.2    Shiffman, M.3    Messinger, D.4    Zeuzem, S.5
  • 100
    • 38649090347 scopus 로고    scopus 로고
    • Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial
    • Mangia A, Minerva N, Bacca D et al. Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial. Hepatology 2008; 47: 43-50.
    • (2008) Hepatology , vol.47 , pp. 43-50
    • Mangia, A.1    Minerva, N.2    Bacca, D.3
  • 101
    • 33749360440 scopus 로고    scopus 로고
    • Effect of ribavirin in genotype 1 patients with hepatitis C responding to pegylated interferon alfa-2a plus ribavirin
    • Bronowicki JP, Ouzan D, Asselah T, Desmorat H et al. Effect of ribavirin in genotype 1 patients with hepatitis C responding to pegylated interferon alfa-2a plus ribavirin. Gastroenterology 2006; 131: 1040-8.
    • (2006) Gastroenterology , vol.131 , pp. 1040-1048
    • Bronowicki, J.P.1    Ouzan, D.2    Asselah, T.3    Desmorat, H.4
  • 102
    • 33750015977 scopus 로고    scopus 로고
    • High efficacy of combined therapy with pegylated interferon plus ribavirin in patients High efficacy of combined therapy with pegylated interferon plus ribavirin in patients with hemophilia and chronic hepatitis C
    • Hepatitis Study Group of the Association of Italian Hemophilia Centers
    • Mancuso ME, Rumi MG, Santagostino E et al. Hepatitis Study Group of the Association of Italian Hemophilia Centers. High efficacy of combined therapy with pegylated interferon plus ribavirin in patients with hemophilia and chronic hepatitis C. Haematologica 2006; 91: 1367-71.
    • (2006) Haematologica , vol.91 , pp. 1367-1371
    • Mancuso, M.E.1    Rumi, M.G.2    Santagostino, E.3
  • 103
    • 34447618045 scopus 로고    scopus 로고
    • Antiviral therapy for chronic hepatitis C in patients with inherited bleeding disorders: An international, multicenter cohort study
    • Posthouwer D, Yee TT, Makris M et al. Antiviral therapy for chronic hepatitis C in patients with inheritedbleeding disorders: An international, multicenter cohort study. J Thromb Haemost. 2007; 5: 1624-9.
    • (2007) J Thromb Haemost , vol.5 , pp. 1624-1629
    • Posthouwer, D.1    Yee, T.T.2    Makris, M.3
  • 104
    • 33645295195 scopus 로고    scopus 로고
    • Predictors of antiviral therapy in a post-transfusion cohort of hepatitis C patients
    • Witkos M, Yi QL, Heathcote J, Kapral MK, Krahn MD. Predictors of antiviral therapy in a post-transfusion cohort of hepatitis C patients. Can J Gastroenterol 2006; 20: 107-11.
    • (2006) Can J Gastroenterol , vol.20 , pp. 107-111
    • Witkos, M.1    Yi, Q.L.2    Heathcote, J.3    Kapral, M.K.4    Krahn, M.D.5
  • 105
    • 19444361816 scopus 로고    scopus 로고
    • Hepatitis C infection among Dutch haemophilia patients: A nationwide cross-sectional study of prevalence and antiviral treatment
    • Posthouwer D, Plug I, van der Bom JG et al. Hepatitis C infection among Dutch haemophilia patients: A nationwide cross-sectional study of prevalence and antiviral treatment. Haemophilia 2005; 11: 270-5.
    • (2005) Haemophilia , vol.11 , pp. 270-275
    • Posthouwer, D.1    Plug, I.2    van der Bom, J.G.3
  • 106
    • 19944430246 scopus 로고    scopus 로고
    • A Canadian multicenter retrospective study evaluating transjugular liver biopsy in patients with congenital bleeding disorders and hepatitis C: Is it safe and useful?
    • Shin JL, Teitel J, Swain MG et al. Virology and Immunology Committee of the Association of Hemophilia Clinic Directors of Canada. A Canadian multicenter retrospective study evaluating transjugular liver biopsy in patients with congenital bleeding disorders and hepatitis C: Is it safe and useful?. Am J Hematol 2005; 78: 85-93.
    • (2005) Am J Hematol , vol.78 , pp. 85-93
    • Shin, J.L.1    Teitel, J.2    Swain, M.G.3
  • 107
    • 33846917303 scopus 로고    scopus 로고
    • Percutaneous liver biopsy in adult haemophiliacs with hepatitis C virus: Safety of outpatient procedure and impact of human immunodeficiency virus co-infection on the spectrum of liver disease
    • Sterling RK, Lyons CD, Stravitz RT et al. Percutaneous liver biopsy in adult haemophiliacs with hepatitis C virus: Safety of outpatient procedure and impact of human immunodeficiency virus co-infection on the spectrum of liver disease. Haemophilia 2007; 13: 164-71.
    • (2007) Haemophilia , vol.13 , pp. 164-171
    • Sterling, R.K.1    Lyons, C.D.2    Stravitz, R.T.3
  • 108
    • 35548957275 scopus 로고    scopus 로고
    • Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients
    • Maor Y, Calès P, Bashari D et al. Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients. Haemophilia 2007; 13: 722-9.
    • (2007) Haemophilia , vol.13 , pp. 722-729
    • Maor, Y.1    Calès, P.2    Bashari, D.3
  • 109
    • 0029854025 scopus 로고    scopus 로고
    • Immunosuppression may lead to progression of hepatitis C virus-associated liver disease in hemophiliacs coinfected with HIV
    • Rockstroh JK, Spengler U, Sudhop T et al. Immunosuppression may lead to progression of hepatitis C virus-associated liver disease in hemophiliacs coinfected with HIV. Am J Gastroenterol 1996; 91: 2563-8.
    • (1996) Am J Gastroenterol , vol.91 , pp. 2563-2568
    • Rockstroh, J.K.1    Spengler, U.2    Sudhop, T.3
  • 110
    • 0035313557 scopus 로고    scopus 로고
    • Impact of human immunodeficiency virus infection on progression to end-stage liver disease in individuals with hemophilia and hepatitis C virus infection
    • Ragni MV, Belle SH. Impact of human immunodeficiency virus infection on progression to end-stage liver disease in individuals with hemophilia and hepatitis C virus infection. J Infect Dis 2001; 183: 1112-5.
    • (2001) J Infect Dis , vol.183 , pp. 1112-1125
    • Ragni, M.V.1    Belle, S.H.2
  • 111
    • 0031912330 scopus 로고    scopus 로고
    • Impact of treatment with human immunodeficiency virus (HIV) protease inhibitors on hepatitis C viremia in patients coinfected with HIV
    • Rutschmann OT, Negro F, Hirschel B, Hadengue A, Anwar D, Perrin LH. Impact of treatment with human immunodeficiency virus (HIV) protease inhibitors on hepatitis C viremia in patients coinfected with HIV. J Infect Dis 1998; 177: 783-5.
    • (1998) J Infect Dis , vol.177 , pp. 783-785
    • Rutschmann, O.T.1    Negro, F.2    Hirschel, B.3    Hadengue, A.4    Anwar, D.5    Perrin, L.H.6
  • 112
    • 0031940475 scopus 로고    scopus 로고
    • Lack of benefit of protease inhibitors on HCV viremia in HIV-infected patients
    • Garcia-Samaniego J, Bravo R, Castilla J et al. Lack of benefit of protease inhibitors on HCV viremia in HIV-infected patients. J Hepatol 1998; 28: 526-7.
    • (1998) J Hepatol , vol.28 , pp. 526-527
    • Garcia-Samaniego, J.1    Bravo, R.2    Castilla, J.3
  • 113
    • 14944382067 scopus 로고    scopus 로고
    • Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection
    • Fialaire P, Payan C, Vitour D et al. Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection. J Infect Dis 1998; 177: 783-5.
    • (1998) J Infect Dis , vol.177 , pp. 783-785
    • Fialaire, P.1    Payan, C.2    Vitour, D.3
  • 115
    • 0037442626 scopus 로고    scopus 로고
    • Progression of chronic hepatitis C to liver fibrosis and cirrhosis in patients coinfected with hepatitis C virus and human immunodeficiency virus
    • Martinez-Sierra C, Arizcorreta A, Díaz F et al. Progression of chronic hepatitis C to liver fibrosis and cirrhosis in patients coinfected with hepatitis C virus and human immunodeficiency virus. Clin Infect Dis 2003; 36: 491-8.
    • (2003) Clin Infect Dis , vol.36 , pp. 491-498
    • Martinez-Sierra, C.1    Arizcorreta, A.2    Díaz, F.3
  • 116
    • 0035822989 scopus 로고    scopus 로고
    • Impact of protease inhibitors on intrahepatic hepatitis C virus viral load
    • Neau D, Trimoulet P, Winnock M et al. Impact of protease inhibitors on intrahepatic hepatitis C virus viral load. AIDS 2001; 15: 1736-8.
    • (2001) AIDS , vol.15 , pp. 1736-1738
    • Neau, D.1    Trimoulet, P.2    Winnock, M.3
  • 117
    • 20144389653 scopus 로고    scopus 로고
    • Short statement of the first European Consensus Conference on the treatment of chronic hepatitis B and C in HIV co-infected patients
    • Alberti A, Clumeck N, Collins S et al. Short statement of the first European Consensus Conference on the treatment of chronic hepatitis B and C in HIV co-infected patients. J Hepatol 2005; 42: 615-24.
    • (2005) J Hepatol , vol.42 , pp. 615-624
    • Alberti, A.1    Clumeck, N.2    Collins, S.3
  • 118
    • 36749020153 scopus 로고    scopus 로고
    • Management and treatment of hepatitis C virus in patients with HIV and hepatitis C virus coinfection: A practical guide for health care professionals
    • Côté P, Baril J, Hébert M et al. Management and treatment of hepatitis C virus in patients with HIV and hepatitis C virus coinfection: A practical guide for health care professionals. Can J Inf Dis Med Micro 2007; 18: 293-303.
    • (2007) Can J Inf Dis Med Micro , vol.18 , pp. 293-303
    • Côté, P.1    Baril, J.2    Hébert, M.3
  • 119
    • 33748751179 scopus 로고    scopus 로고
    • Zidovudine use but not weight-based ribavirin dosing impacts anaemia during HCV treatment in HIV-infected persons
    • Alvarez D, Dieterich DT, Brau N, Moorehead L, Ball L, Sulkowski MS. Zidovudine use but not weight-based ribavirin dosing impacts anaemia during HCV treatment in HIV-infected persons. J Viral Hepat 2006; 13: 683-9.
    • (2006) J Viral Hepat , vol.13 , pp. 683-689
    • Alvarez, D.1    Dieterich, D.T.2    Brau, N.3    Moorehead, L.4    Ball, L.5    Sulkowski, M.S.6
  • 120
    • 1642423882 scopus 로고    scopus 로고
    • Didanosine-ribavirin combination: Synergistic combination in vitro, but high potential risk of toxicity in vivo
    • Bruno R, Sacchi P, Filice G. Didanosine-ribavirin combination: synergistic combination in vitro, but high potential risk of toxicity in vivo. AIDS 2003; 17: 2674-5.
    • (2003) AIDS , vol.17 , pp. 2674-2675
    • Bruno, R.1    Sacchi, P.2    Filice, G.3
  • 121
    • 0032484123 scopus 로고    scopus 로고
    • Peroxysome proliferator-activated receptor an activation modulates cellular redox status, represses nuclear factor kB signaling, and reduces inflammatory cytokine production in aging
    • Poynter ME, Daynes RA. Peroxysome proliferator-activated receptor an activation modulates cellular redox status, represses nuclear factor kB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 1998; 273: 32833-41.
    • (1998) J Biol Chem , vol.273 , pp. 32833-32841
    • Poynter, M.E.1    Daynes, R.A.2
  • 122
    • 0033520109 scopus 로고    scopus 로고
    • Interferon therapy reduces the risk for hepatocellular carcinoma: National surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan
    • IHIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy
    • Yoshida H, Shiratori Y, Moriyama M et al. Interferon therapy reduces the risk for hepatocellular carcinoma: National surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy. Ann Intern Med 1999; 131: 174-81.
    • (1999) Ann Intern Med , vol.131 , pp. 174-181
    • Yoshida, H.1    Shiratori, Y.2    Moriyama, M.3
  • 123
    • 0036242165 scopus 로고    scopus 로고
    • Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
    • Poynard T, McHutchison J, Manns M et al. Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 2002; 122: 1303-13.
    • (2002) Gastroenterology , vol.122 , pp. 1303-1313
    • Poynard, T.1    McHutchison, J.2    Manns, M.3
  • 124
    • 10744232465 scopus 로고    scopus 로고
    • Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: A meta-analysis of individual patient data
    • Camma' C, Di Bona D, Schepis F et al. Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: A meta-analysis of individual patient data. Hepatology 2004; 39: 333-42.
    • (2004) Hepatology , vol.39 , pp. 333-342
    • Camma', C.1    Di Bona, D.2    Schepis, F.3
  • 125
    • 34547499913 scopus 로고    scopus 로고
    • Management of chronic hepatitis C: Consensus guidelines
    • Sherman M, Shafran S, Burak K et al. Management of chronic hepatitis C: consensus guidelines. Can J Gastroenterol 2007; 21: 25C-34C.
    • (2007) Can J Gastroenterol , vol.21
    • Sherman, M.1    Shafran, S.2    Burak, K.3
  • 126
    • 9644262441 scopus 로고    scopus 로고
    • Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levels
    • PEGASYS Study NR16071 Investigator Group
    • Zeuzem S, Diago M, Gane E et al. PEGASYS Study NR16071 Investigator Group. Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levels. Gastroenterology 2004; 127: 1724-32.
    • (2004) Gastroenterology , vol.127 , pp. 1724-1732
    • Zeuzem, S.1    Diago, M.2    Gane, E.3
  • 127
    • 34548304887 scopus 로고    scopus 로고
    • Haematological support during peg-interferon therapy for HCV-infected haemophiliacs improves virological outcomes
    • Kevans D, Farrell G, Hopkins S et al. Haematological support during peg-interferon therapy for HCV-infected haemophiliacs improves virological outcomes. Haemophilia 2007; 13: 593-8.
    • (2007) Haemophilia , vol.13 , pp. 593-598
    • Kevans, D.1    Farrell, G.2    Hopkins, S.3
  • 128
    • 10644237092 scopus 로고    scopus 로고
    • Epoetin alfa improves quality of life in anemic HCV-infected patients receiving combination therapy
    • Pockros PJ, Shiffman ML, Schiff ER et al. Epoetin alfa improves quality of life in anemic HCV-infected patients receiving combination therapy. Hepatology 2004; 40: 1450-8.
    • (2004) Hepatology , vol.40 , pp. 1450-1458
    • Pockros, P.J.1    Shiffman, M.L.2    Schiff, E.R.3
  • 129
    • 11144358403 scopus 로고    scopus 로고
    • Epoetin alfa maintains ribavirin dose in HCV-infected patients: A prospective, double-blind, randomized controlled study
    • Afdhal NH, Dieterich DT, Pockros PJ et al. Epoetin alfa maintains ribavirin dose in HCV-infected patients: A prospective, double-blind, randomized controlled study. Gastroenterology 2004; 126: 1302-11.
    • (2004) Gastroenterology , vol.126 , pp. 1302-1311
    • Afdhal, N.H.1    Dieterich, D.T.2    Pockros, P.J.3
  • 130
    • 35248887966 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor dosing in pegylated interferon alpha-induced neutropenia and its impact on outcome of anti-HCV therapy
    • Koirala J, Gandotra SD, Rao S et al. Granulocyte colony-stimulating factor dosing in pegylated interferon alpha-induced neutropenia and its impact on outcome of anti-HCV therapy. J Viral Hepat 2007; 14: 782-7.
    • (2007) J Viral Hepat , vol.14 , pp. 782-787
    • Koirala, J.1    Gandotra, S.D.2    Rao, S.3
  • 131
    • 11144252779 scopus 로고    scopus 로고
    • The use of growth factors to manage the hematologic side effects of PEG-interferon alfa and ribavirin
    • Collantes RS, Younossi ZM. The use of growth factors to manage the hematologic side effects of PEG-interferon alfa and ribavirin. J Clin Gastroenterol 2005; 39: S9-13.
    • (2005) J Clin Gastroenterol , vol.39
    • Collantes, R.S.1    Younossi, Z.M.2
  • 132
    • 36549047972 scopus 로고    scopus 로고
    • Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
    • McHutchison JG, Dusheiko G, Shiffman ML et al. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med 2007; 357: 2227-36.
    • (2007) N Engl J Med , vol.357 , pp. 2227-2236
    • McHutchison, J.G.1    Dusheiko, G.2    Shiffman, M.L.3
  • 133
    • 41149140327 scopus 로고    scopus 로고
    • Therapy of interferon-induced depression in chronic hepatitis C with citalopram: A randomized, double-blind, placebo-controlled study
    • Kraus MR, Schäfer A, Schöttker K et al. Therapy of interferon-induced depression in chronic hepatitis C with citalopram: A randomized, double-blind, placebo-controlled study. Gut 2008; 57: 531-6.
    • (2008) Gut , vol.57 , pp. 531-536
    • Kraus, M.R.1    Schäfer, A.2    Schöttker, K.3
  • 134
    • 34247550405 scopus 로고    scopus 로고
    • Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis C
    • Raison CL, Woolwine BJ, Demetrashvili MF et al. Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis C. Aliment Pharmacol Ther 2007; 25: 1163-74.
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 1163-1174
    • Raison, C.L.1    Woolwine, B.J.2    Demetrashvili, M.F.3
  • 135
    • 7444271382 scopus 로고    scopus 로고
    • Impact of a designated hepatology nurse on the clinical course and quality of life of patients treated with rebetron therapy for chronic hepatitis C
    • Ahern M, Imperial J, Lam S. Impact of a designated hepatology nurse on the clinical course and quality of life of patients treated with rebetron therapy for chronic hepatitis C. Gastroenterol Nurs 2004; 27: 149-55.
    • (2004) Gastroenterol Nurs , vol.27 , pp. 149-155
    • Ahern, M.1    Imperial, J.2    Lam, S.3
  • 136
    • 34547399496 scopus 로고    scopus 로고
    • The role of hepatology nurse in the difficult-to-treat hepatitis C population
    • Ford JA, Cheong-Lee C. The role of hepatology nurse in the difficult-to-treat hepatitis C population. Can J Gastroenterol 2007; 21: 353-4.
    • (2007) Can J Gastroenterol , vol.21 , pp. 353-354
    • Ford, J.A.1    Cheong-Lee, C.2
  • 137
    • 11144325749 scopus 로고    scopus 로고
    • Impact of adherence on the outcome of antiviral therapy for chronic hepatitis C
    • Mulhall BP, Younossi Z. Impact of adherence on the outcome of antiviral therapy for chronic hepatitis C. J Clin Gastroenterol 2005; 39: S23-7.
    • (2005) J Clin Gastroenterol , vol.39
    • Mulhall, B.P.1    Younossi, Z.2
  • 138
    • 0036788338 scopus 로고    scopus 로고
    • Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C
    • McHutchison JG, Manns M, Patel K et al. Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C. Gastroenterology 2002; 123: 1061-9.
    • (2002) Gastroenterology , vol.123 , pp. 1061-1069
    • McHutchison, J.G.1    Manns, M.2    Patel, K.3
  • 139
    • 17044412029 scopus 로고    scopus 로고
    • Estimating the impact of hepatitis C virus therapy on future liver-related morbidity, mortality and costs related to chronic hepatitis C
    • Buti M, San Miguel R, Brosa M et al. Estimating the impact of hepatitis C virus therapy on future liver-related morbidity, mortality and costs related to chronic hepatitis C. J Hepatol 2005; 42: 639-45.
    • (2005) J Hepatol , vol.42 , pp. 639-645
    • Buti, M.1    San Miguel, R.2    Brosa, M.3
  • 140
    • 4444304792 scopus 로고    scopus 로고
    • Past, present, and future hepatitis C treatments
    • Foster GR. Past, present, and future hepatitis C treatments. Semin Liver Dis 2004; 24: 97-104.
    • (2004) Semin Liver Dis , vol.24 , pp. 97-104
    • Foster, G.R.1
  • 141
    • 14644402363 scopus 로고    scopus 로고
    • Current and future concepts in hepatitis C therapy
    • Pawlotsky JM. Current and future concepts in hepatitis C therapy. Semin Liver Dis 2005; 25: 72-83.
    • (2005) Semin Liver Dis , vol.25 , pp. 72-83
    • Pawlotsky, J.M.1
  • 142
    • 33646388715 scopus 로고    scopus 로고
    • HCV RNA results from a phase II, randomized, open-label study of omega interferon (IFN) with or without ribavirin in IFN-näive genotype 1 chronic HCV patients
    • Gorbakov VV, Kim H, Oronsky B, Lang W. HCV RNA results from a phase II, randomized, open-label study of omega interferon (IFN) with or without ribavirin in IFN-näive genotype 1 chronic HCV patients. Hepatology 2005; 42: 705A.
    • (2005) Hepatology , vol.42
    • Gorbakov, V.V.1    Kim, H.2    Oronsky, B.3    Lang, W.4
  • 143
    • 30344483500 scopus 로고    scopus 로고
    • A phase 2 study of albuferon in combination with ribavirin in non-responders to prior interferon therapy for chronic hepatitis C
    • Nelson D, Rustgi V, Balan V et al. A phase 2 study of albuferon in combination with ribavirin in non-responders to prior interferon therapy for chronic hepatitis C. Hepatology 2005; 42: 278A.
    • (2005) Hepatology , vol.42
    • Nelson, D.1    Rustgi, V.2    Balan, V.3
  • 144
    • 0036827834 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-alpha fusion protein in cynomolgus monkeys
    • Osborn BL, Olsen HS, Nardelli B et al. Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-alpha fusion protein in cynomolgus monkeys. J Pharmacol Exp Ther 2002; 303: 540-8.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 540-548
    • Osborn, B.L.1    Olsen, H.S.2    Nardelli, B.3
  • 145
    • 30344435164 scopus 로고    scopus 로고
    • Virologic response and safety outcomes in therapy-näive patients treated for chronic hepatitis C with viramidine in combination with pegylated interferon-2a
    • Gish RG, Nelson D, Arora S et al. Virologic response and safety outcomes in therapy-näive patients treated for chronic hepatitis C with viramidine in combination with pegylated interferon-2a. J Hepatol 2005; 42: 39.
    • (2005) J Hepatol , vol.42 , pp. 39
    • Gish, R.G.1    Nelson, D.2    Arora, S.3
  • 146
    • 34247594930 scopus 로고    scopus 로고
    • Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir
    • Sarrazin C, Kieffer TL, Bartels D et al. Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology 2007; 132: 1767-77.
    • (2007) Gastroenterology , vol.132 , pp. 1767-1777
    • Sarrazin, C.1    Kieffer, T.L.2    Bartels, D.3
  • 147
    • 36749079979 scopus 로고    scopus 로고
    • Interim analysis results from a phase 2 study of telaprevir with peginterferon Alfa-2a and ribavirin in treatment-naïve subjects with Hepatitis C
    • Jacobson IM, Everson GT, Gordon SC et al. Interim analysis results from a phase 2 study of telaprevir with peginterferon Alfa-2a and ribavirin in treatment-naïve subjects with Hepatitis C. Hepatology 2007; 47: Abstract 177.
    • (2007) Hepatology , vol.47
    • Jacobson, I.M.1    Everson, G.T.2    Gordon, S.C.3
  • 148
    • 41749110164 scopus 로고    scopus 로고
    • PROVE2: Phase II study of Vx950 (Telaprevir) in combination with peginterferon Alfa2a with or without ribavirin in subjects with chronic hepatitis C, first interim analysis
    • Abstract 80
    • Hezode C, Ferenci P, Dusheik GM, Pol S, Goeser T, Bronowicki J et al. PROVE2: Phase II study of Vx950 (Telaprevir) in combination with peginterferon Alfa2a with or without ribavirin in subjects with chronic hepatitis C, first interim analysis. Hepatology 2007; 47: Abstract 80.
    • (2007) Hepatology , vol.47
    • Hezode, C.1    Ferenci, P.2    Dusheik, G.M.3    Pol, S.4    Goeser, T.5    Bronowicki, J.6
  • 149
    • 41749089249 scopus 로고    scopus 로고
    • Robust synergistic antiviral effect of R1626 in combination with peginterferon Alfa-2a (40kd), with or without ribavirin - Interim analysis results of phase 2a study
    • Abstract 167
    • Pockros PJ, Nelson D, Godofsky E, Rodriguez-Torres M, Everson G, Fried MW et al. Robust synergistic antiviral effect of R1626 in combination with peginterferon Alfa-2a (40kd), with or without ribavirin - interim analysis results of phase 2a study. Analysis Hepatology 2007; 47: Abstract 167.
    • (2007) Hepatology , vol.47
    • Pockros, P.J.1    Nelson, D.2    Godofsky, E.3    Rodriguez-Torres, M.4    Everson, G.5    Fried, M.W.6
  • 150
    • 0038580440 scopus 로고    scopus 로고
    • A multicenter study of recombinant human interleukin 12 for the treatment of chronic hepatitis C virus infection in patients nonresponsive to previous therapy
    • Pockros PJ, Patel K, O'Brien C et al. A multicenter study of recombinant human interleukin 12 for the treatment of chronic hepatitis C virus infection in patients nonresponsive to previous therapy. Hepatology 2003; 37: 1368-74.
    • (2003) Hepatology , vol.37 , pp. 1368-1374
    • Pockros, P.J.1    Patel, K.2    O'Brien, C.3
  • 151
    • 37549014866 scopus 로고    scopus 로고
    • Vaccination against hepatitis C virus with dendritic cells transduced with an adenovirus encoding NS3 protein
    • Zabaleta A, Llopiz D, Arribillaga L et al. Vaccination against hepatitis C virus with dendritic cells transduced with an adenovirus encoding NS3 protein. Mol Ther 2008; 16: 210-7.
    • (2008) Mol Ther , vol.16 , pp. 210-217
    • Zabaleta, A.1    Llopiz, D.2    Arribillaga, L.3
  • 152
    • 37549028770 scopus 로고    scopus 로고
    • The functional evaluation of dendritic cell vaccines based on different hepatitis C virus nonstructural genes
    • Tian Y, Zhang HH, Wei L et al. The functional evaluation of dendritic cell vaccines based on different hepatitis C virus nonstructural genes. Viral Immunol 2007; 20: 553-61.
    • (2007) Viral Immunol , vol.20 , pp. 553-561
    • Tian, Y.1    Zhang, H.H.2    Wei, L.3
  • 153
    • 42949111104 scopus 로고    scopus 로고
    • Therapeutic vaccination of chronic hepatitis C nonresponder patients with the peptide vaccine IC41
    • Klade CS, Wedemeyer H, Berg T et al. Therapeutic vaccination of chronic hepatitis C nonresponder patients with the peptide vaccine IC41. Gastroenterology 2008; 134: 1385-95.
    • (2008) Gastroenterology , vol.134 , pp. 1385-1395
    • Klade, C.S.1    Wedemeyer, H.2    Berg, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.