CR1 levels and gene polymorphisms exhibit differential association with falciparum malaria in regions of varying disease endemicity

Human Immunology

Volumn 70, Issue 4, 2009, Pages 244-250

  Sinha, Swapnil ^a   Jha, Ganga N ^a   Anand, Prerna ^b   Qidwai, Tabish ^a   Pati, Sudhanshu S ^c   Mohanty, Sanjib ^c   Mishra, Saroj K ^c   Tyagi, Prajesh K ^d   Sharma, Surya K ^d   Venkatesh, Vimala ^b   Habib, Saman ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b KING GEORGE'S MEDICAL UNIVERSITY   (India)

^c ISPAT GENERAL HOSPITAL   (India)

^d NATIONAL INSTITUTE OF MALARIA RESEARCH   (India)

Author keywords

CD35; Disease pathogenesis; Malaria; Plasmodium falciparum; Severe anemia; SNPs

Indexed keywords

COMPLEMENT COMPONENT C3B RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE PREDISPOSITION; ENDEMIC DISEASE; ERYTHROCYTE; EXON; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INDIAN; INFECTION RISK; INTRON; MALARIA FALCIPARUM; MALE; PATHOGENESIS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; ALLELES; CASE-CONTROL STUDIES; ENDEMIC DISEASES; ERYTHROCYTES; EXONS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIA; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, COMPLEMENT 3B; RISK FACTORS; YOUNG ADULT;

EID: 62949243410     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.02.001     Document Type: Article

References (40)

1. Kwiatkowski D. How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 77 (2005) 171-192
2. Hedrick P. Estimation of relative fitness from relative risk data and the predicted future of hemoglobin alleles S and C. J Evol Biol 17 (2004) 221-224
3. Williams T.N., Wambua S., Uyoga S., Macharia A., and Mwacharo J.K. Both heterozygous and homozygous α-thalassemia protect against severe and fatal Plasmodium falciparum malaria on the coast of Kenya. Blood 106 (2005) 368-371
4. Tishkoff S.A., Varkonyi R., Cahinhinan N., Abbes S., Argyropoulos G., Destro-Bisol G., et al. Haplotype diversity and linkage disequilibrium at human G6PD: Recent origin of alleles that confer malarial resistance. Science 293 (2001) 455-462
5. Cockburn I.A., Mackinnon M.J., O'Donnell A., Allen S.J., Moulds J.M., Baisor M., et al. A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria. Proc Natl Acad Sci USA 101 (2004) 272-277
6. Nagayasu E., Ito M., Akaki M., Nakano Y., Kimura M., Looareesuwan S., and Aikawa M. CR1 density polymorphism on erythrocytes of falciparum malaria patients in Thailand. Am J Trop Med Hyg 64 (2001) 1-5
7. Roozendaal R., and Carroll M.C. Complement receptors CD21 and CD35 in humoral immunity. Immunol Rev 219 (2007) 157-166
8. Krych-Goldberg M., and Atkinson J.P. Structure-function relationships of copmplement receptor type-1. Immunol Rev 180 (2001) 112-122
9. Schifferli J.A., Ng Y.C., Paccaud J.P., and Walport M.J. The role of hypocomplemetemia and low erythrocyte complement receptor type 1 numbers in determining abnormal immune complex clearance in humans. Clin Exp Immunol 75 (1989) 329-335
10. Rowe J.A., Moulds J.M., Newbold C.I., and Miller L.H. P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement receptor 1. Nature 388 (1997) 292-295
11. Rowe J.A., Rogerson S.J., Raza A., Mould J.M., Kazatchkine M.D., Marsh K., et al. Mapping of the region of complement receptor (CR) 1 required for Plasmodium falciparum rosetting and demonstration of the importance of CR1 in rosetting in field isolates. J Immunol 165 (2000) 6341-6346
12. Krych-Goldberg M., Moulds J.M., and Atkinson J.P. Human complement receptor type 1 (CR1) binds to a major malarial adhesin. TRENDS Mol Med 8 (2002) 631-637
13. Xiang L., Rundles J.R., Hamilton D.R., and Wilson J.G. Quantitative alleles of CR1: Coding sequence analysis and comparison of haplotypes in two ethnic groups. J Immunol 163 (1999) 4939-4945
14. Thomas B.N., Donvito B., Cockburn I., Fandeur T., Rowe J.A., Cohen J.H.M., and Moulds J.M. A complement receptor-1 polymorphism with high frequency in malaria endemic regions of Asia but not Africa. Genes Immun 6 (2005) 31-36
15. Birmingham D.J., Chen W., Liang G., Schmitt C., Gavit K., and Nagaraja H.N. A CR1 polymorphism associated with constitutive erythrocyte CR1 levels affects binding to C4b but not C3b. Immunology 108 (2003) 531-538
16. Herrera A.H., Xiang L., Martin S.G., Lewis J., and Wilson J.G. Analysis of complement receptor type 1 (CR1) expression on erythrocytes and of CR1 allelic markers in Caucasian and African American populations. Clin Immunol Immunopathol 87 (1998) 176-183
17. Rowe J.A., Raza A., Diallo D.A., Baby M., Poudiougo B., Coulibaly D., et al. Erythrocyte complement receptor 1 expression levels do not correlate with a Hind III restriction fragment length polymorphism in Africans: Implications for studies on malaria susceptibility. Genes Immun 3 (2002) 497-500
18. Bellamy R., Kwiatkowski D., and Hill A.V. Absence of an association between intercellular adhesion molecule 1, complement receptor 1 and interleukin 1 receptor antagonist gene polymorphisms and severe malaria in a West African population. Trans R Soc Trop Med Hyg 92 (1998) 312-316
19. Indian Genome Variation Consortium. Genetic landscape of the people of India: a canvas for disease-gene exploration. J Genet 87 (2008) 3-20
20. Patsoula E., Spanakos G., Sofianatou D., Parara M., and Vakalis N.C. A single-step, PCR-based method for the detection and differentiation of Plasmodium vivax and P. falciparum. Ann Trop Med Parasitol 97 (2003) 15-21
21. World Health Organization. Severe falciparum malaria. Trans R Soc Trop Med Hyg 94 Suppl 1 (2000)
22. Sinha S., Mishra S.K., Sharma S., Patibandla P.K., Mallick P.K., Sharma S.K., et al. Polymorphisms of TNF-enhancer and gene for FcγRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Malar J 7 (2008) 13
23. Cockburn I.A., Donvito B., Cohen J.H.M., and Rowe J.A. A simple method for accurate quantification of complement receptor 1 on erythrocytes preserved by fixing or freezing. J Immunol Methods 271 (2002) 59-64
24. Cohen J.H.M., Aubry J.P., Jouvin M.H., Wijdenes J., Bancherau J., Kazatchkine M., and Revillard J.P. Enumeration of CR1 complement receptors on erythrocytes using a new method for detecting low density cell surface antigens by flow cytometry. J Immunol Methods 99 (1987) 53-58
25. Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16 (1998) 1215
26. Cornillet P., Philbert F., Katachkine M.D., and Cohen J.H.M. Genomic determination of CR1 (CD35) density polymorphism on erythrocytes using polymerase chain reaction amplification and HindIII restriction enzyme digestion. J Immunol Methods 136 (1991) 193-197
27. Katyal M., Sivasankar B., Ayub S., and Das N. Genetic and structural polymorphism of complement receptor 1 in normal Indian subjects. Immunol Lett 89 (2003) 93-98
28. Mibei E.K., Orago A.S.S., and Stoute J.A. Immune complex levels in children with severe Plasmodium falciparum malaria. Am J Trop Med Hyg 72 (2005) 593-599
29. Virella G., Atchley D., Koskinen S., Zheng D., and Lopes-Virella M.F. DCCT/EDIC Reseach grouP. Proatherogenic and proinflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL. Clin Immunol 105 (2002) 81-92
30. Gomez Guerrero C., Lopez-Franco O., Suzuki Y., Sanjuan G., Hernandez-Vargas P., Blanco J., and Egido J. Nitric oxide production in renal cells by immune complexes: Role of kinases and nuclear factor-κB. Kidney Int 62 (2002) 2022-2024
31. Chou Y.K., Shewood T., and Virella G. Erythrocyte-bound immune complexes trigger the release of interleukin-1 from human monocytes. Cell Immunol 91 (1985) 308-314
32. Stoute J.A. Complement-regulatory proteins in severe malaria: Too little or too much of a good thing?. TRENDS Parasitol 21 (2005) 218-222
33. Clark I.A., and Chaudhri G. Tumour necrosis factor may contribute to the anemia of malaria by causing dyserythropoiesis and erythrophagocytosis. Br J Hematol 70 (1998) 99-103
34. Singh N., Mishra A.K., Shukla M.M., and Chand S.K. Forest malaria in Chhindwara, Madhya pradesh, central India: A case study in a tribal community. Am J Trop Med Hyg 68 (2003) 602-607
35. Sharma S.K., Chattopadhyay R., Chakrabarti K., Pati S.S., Srivastava V.K., Tyagi P.K., et al. Epidemiology of malaria transmission and development of natural immunity in a malaria-endemic village, San Dulakudar, in Orissa state. India Am J Trop Med Hyg 71 (2004) 457-465
36. Wilson J.G., Murphy E.E., Wong W.W., Klickstein L.B., Weis G.H., and Fearon D.T. Identification of restriction fragment length polymorphism by a CR1 cDNA that correlates with the number of CR1 on erythrocytes. J Exp Med 164 (1986) 50-59
37. Norman D.G., Barlow P.N., Baron M., Day A.J., Sim R.B., and Campbell I.D. Three-dimensional structure of a complement control protein module in solution. J Mol Biol 219 (1991) 717-725
38. Reinagel M.L., and Taylor R.P. Transfer of immune complexes from erythrocyte CR1 to mouse macrophages. J Immunol 164 (2000) 1977-1985
39. Waitumbi J.N., Opollo M.O., Muga R.O., Misore A.O., and Stoute J.A. Red cell surface changes and erythrophagocytosis in children with severe Plasmodium falcipraum anemia. Blood 95 (2000) 1481-1486
40. Owour B.O., Odhiambo C.O., Otieno W.O., Adhiambo C., Makawiti D.W., and Stoute J.A. Reduced immune complex binding capacity and increased complement susceptibility of red cells from children with severe malaria-associated anemia. Mol Med 14 (2008) 89-97