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Volumn , Issue 7, 2009, Pages 821-823

A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes

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EID: 62949188352     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b817357e     Document Type: Article
Times cited : (24)

References (16)
  • 11
    • 0036700364 scopus 로고    scopus 로고
    • A spacer consisting of two glycine residues was introduced, because originally we experienced problems in attaching cyclic peptides to the TAC scaffold, which we ascribed to steric hindrance The cleavage and mass analysis of an aliquot of resin showed that the synthesis had successfully reached this stage Ammonium acetate buffers were used for purification in view of the presence of an Asp-Pro sequence in the first loop, which is prone to cleavage under acidic conditions
    • M. Wagner H. Kunz Z. Naturforsch., B: Chem. Sci. 2002 57b 928
    • (2002) Z. Naturforsch., B: Chem. Sci. , vol.57 , pp. 928
    • Wagner, M.1    Kunz, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.