Real-time monitoring of force response measured in mechanically stimulated tissue-engineered cartilage

Artificial Organs

Volumn 33, Issue 4, 2009, Pages 318-327

  Preiss Bloom, Orahn ^a   Mizrahi, Joseph ^a   Elisseeff, Jennifer ^b   Seliktar, Dror ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b Johns Hopkins University School of Medicine   (United States)

Author keywords

Biomechanics; Chondrocytes; Mechanical stimulation; Poly(ethylene glycol); Tissue engineering

Indexed keywords

BODY FLUIDS; CARTILAGE; ETHYLENE GLYCOL; POLYOLS; STIFFNESS; STRUCTURAL PROPERTIES; TISSUE ENGINEERING;

BIOCHEMICAL COMPOSITION; CHONDROCYTES; COMPOSITIONAL CHANGES; COMPRESSIVE MODULI; FORCE RESPONSE; MECHANICAL STIMULATION; REAL TIME MONITORING; TISSUE ENGINEERED CARTILAGE; TISSUES ENGINEERINGS;

POLYETHYLENE GLYCOLS;

MACROGOL;

ANIMAL CELL; ARTICLE; BIOREACTOR; CARTILAGE CELL; CARTILAGE GRAFT; CONTROLLED STUDY; FORCE; HYDROGEL; MECHANICAL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PRODUCT DEVELOPMENT; RIGIDITY; YOUNG MODULUS;

EID: 62949126643     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2009.00723.x     Document Type: Article

References (33)

1. Mankin HJ, Mow VC, Buckwalter JA, Iannotti JP, Ratcliffe A. Form and function of articular cartilage. In : Simon SR, ed. Orthopaedic Basic Science. Roseville, IL : American Academy of Orthopaedic Surgeons, 1994 1 44.
2. Silver FH, Siperko LM. Mechanosensing and mechanochemical transduction: how is mechanical energy sensed and converted into chemical energy in an extracellular matrix? Crit Rev Biomed Eng 2003 31 : 255 331.
3. Kuo CK, Li WJ, Mauck RL, Tuan RS. Cartilage tissue engineering: its potential and uses. Curr Opin Rheumatol 2006 18 : 64 73.
4. Hunter CJ, Imler SM, Malaviya P, Nerem RM, Levenston ME. Mechanical compression alters gene expression and extracellular matrix synthesis by chondrocytes cultured in collagen I gels. Biomaterials 2002 23 : 1249 59.
5. Hunter CJ, Levenston ME. Maturation and integration of tissue-engineered cartilages within an in vitro defect repair model. Tissue Eng 2004 10 : 736 46.
6. Grodzinsky AJ, Levenston ME, Jin M, Frank EH. Cartilage tissue remodeling in response to mechanical forces. Annu Rev Biomed Eng 2000 2 : 691 713.
7. Quinn TM, Grodzinsky AJ, Buschmann MD, Kim YJ, Hunziker EB. Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants. J Cell Sci 1998 111 (Pt 5 573 83.
8. Sah RL, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch Biochem Biophys 1991 286 : 20 9.
9. Sah RL, Grodzinsky AJ, Plaas AH, Sandy JD. Effects of tissue compression on the hyaluronate-binding properties of newly synthesized proteoglycans in cartilage explants. Biochem J 1990 267 : 803 8.
10. Sah RL, Kim YJ, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 1989 7 : 619 36.
11. Freed LE, Guilak F, Guo XE, et al. Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling. Tissue Eng 2006 12 : 3285 305.
12. Mauck RL, Soltz MA, Wang CC, et al. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 2000 122 : 252 60.
13. Demarteau O, Jakob M, Schafer D, Heberer M, Martin I. Development and validation of a bioreactor for physical stimulation of engineered cartilage. Biorheology 2003 40 : 331 6.
14. Seidel JO, Pei M, Gray ML, Langer R, Freed LE, Vunjak-Novakovic G. Long-term culture of tissue engineered cartilage in a perfused chamber with mechanical stimulation. Biorheology 2004 41 : 445 58.
15. Kelly TA, Wang CC, Mauck RL, Ateshian GA, Hung CT. Role of cell-associated matrix in the development of free-swelling and dynamically loaded chondrocyte-seeded agarose gels. Biorheology 2004 41 : 223 37.
16. Hunter CJ, Levenston ME. The influence of repair tissue maturation on the response to oscillatory compression in a cartilage defect repair model. Biorheology 2002 39 : 79 88.
17. Mauck RL, Seyhan SL, Ateshian GA, Hung CT. Influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyte-seeded agarose hydrogels. Ann Biomed Eng 2002 30 : 1046 56.
18. De Croos JN, Dhaliwal SS, Grynpas MD, Pilliar RM, Kandel RA. Cyclic compressive mechanical stimulation induces sequential catabolic and anabolic gene changes in chondrocytes resulting in increased extracellular matrix accumulation. Matrix Biol 2006 25 : 323 31.
19. Lu L, Zhu X, Valenzuela RG, Currier BL, Yaszemski MJ. Biodegradable polymer scaffolds for cartilage tissue engineering. Clin Orthop Relat Res 2001 October (Suppl 391 S251 70.
20. Nesic D, Whiteside R, Brittberg M, Wendt D, Martin I, Mainil-Varlet P. Cartilage tissue engineering for degenerative joint disease. Adv Drug Deliv Rev 2006 58 : 300 22.
21. Schmidt O, Mizrahi J, Elisseeff J, Seliktar D. Immobilized fibrinogen in PEG hydrogels does not improve chondrocyte-mediated matrix deposition in response to mechanical stimulation. Biotechnol Bioeng 2006 95 : 1061 9.
22. Terraciano V, Hwang N, Moroni L, et al. Differential response of adult and embryonic mesenchymal progenitor cells to mechanical compression in hydrogels. Stem Cells 2007 25 : 2730 8.
23. Elisseeff J, Anseth K, Sims D, et al. Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage. Plast Reconstr Surg 1999 104 : 1014 22.
24. Lum LY, Elisseeff J. Injectable hydrogels for cartilage tissue engineering. In : Ashammakhi N, Ferretti P, eds. Topics in Tissue Engineering. Oulu University Hospital, Oulu, Finland, 2003 Ch. 4, 1 25. e-book.
25. Williams CG, Malik AN, Kim TK, Manson PN, Elisseeff JH. Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation. Biomaterials 2005 26 : 1211 8.
26. Bryant SJ, Anseth KS. Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels. J Biomed Mater Res 2002 59 : 63 72.
27. Bryant SJ, Anseth KS, Lee DA, Bader DL. Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. J Orthop Res 2004 22 : 1143 9.
28. Waldman SD, Spiteri CG, Grynpas MD, Pilliar RM, Kandel RA. Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. Tissue Eng 2004 10 : 1323 31.
29. Lee DA, Bader DL. Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose. J Orthop Res 1997 15 : 181 8.
30. Davisson T, Kunig S, Chen A, Sah R, Ratcliffe A. Static and dynamic compression modulate matrix metabolism in tissue engineered cartilage. J Orthop Res 2002 20 : 842 8.
31. Fehrenbacher A, Steck E, Roth W, Pahmeier A, Richter W. Long-term mechanical loading of chondrocyte-chitosan biocomposites in vitro enhanced their proteoglycan and collagen content. Biorheology 2006 43 : 709 20.
32. Kisiday JD, Jin M, DiMicco MA, Kurz B, Grodzinsky AJ. Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds. J Biomech 2004 37 : 595 604.
33. Mauck RL, Wang CC, Oswald ES, Ateshian GA, Hung CT. The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading. Osteoarthritis Cartilage 2003 11 : 879 90.