Synthesis of [3H]ABT-518, a matrix metalloproteinase inhibitor (MMPI) labeled in the phenyl rings

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 52, Issue 3, 2009, Pages 98-102

  Raja, Shirish N ^a   Surber, Bruce W ^a   Du, Jia ^a   Cross, Jeffrey L ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

1 (methylsulfonyl) 4 4 (trifluoromethoxy)phenoxy benzene; ABT 518; Matrix metalloproteinase inhibitors; MMPI

Indexed keywords

ENZYME INHIBITION;

1-(METHYLSULFONYL)-4-[4- (TRIFLUOROMETHOXY)PHENOXY]BENZENE; ABT-518; MATRIX; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE INHIBITORS; PHENYL RINGS; RADIOCHEMICAL YIELD;

BENZENE;

MATRIX METALLOPROTEINASE INHIBITOR; N [1 (2,2 DIMETHYL 1,3 DIOXOL 4 YL) 2 ((4 (4 TRIFLUOROMETHOXY)PHENOXY)PHENYL)SULFONYL)ETHYL] N HYDROXYFORMAMIDE; RADIOPHARMACEUTICAL AGENT; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; IN VITRO STUDY; ISOTOPE LABELING; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTUM YIELD; RADIOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

EID: 62849119302     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1574     Document Type: Article

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