Selective [15Nη2] labelling of an NG-propionylated arginine derivative

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 52, Issue 2, 2009, Pages 29-32

  Kleinmaier, Roland ^a   Gschwind, Ruth M ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

15N labelling; Arginine; S methylisothiourea

Indexed keywords

CHEMICAL REACTIONS; CHLORINE COMPOUNDS; MERCURY COMPOUNDS;

15-N LABELING; ACYLATED PRODUCTS; AMINO GROUP; CONVERGENT SYNTHESIS; LABELINGS; S-METHYLISOTHIOUREA; SIDE-CHAINS; TITLE COMPOUNDS;

ARGININE;

ARGININE DERIVATIVE; MERCURIC CHLORIDE; N (TERT BUTOXYCARBONYL) N'(PROPIONYL) S METHYLISOTHIOREA N 15; NITROGEN 15; ORNITHINE; UNCLASSIFIED DRUG;

ARTICLE; ISOTOPE LABELING; STOICHIOMETRY; SYNTHESIS;

NETA;

EID: 62849118049     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1564     Document Type: Article

References (22)

1. G. Federwisch, R. Kleinmaier, D. Drettwan, R. M. Gschwind, J. Am. Chem. Soc. 2008, under revision.
2. R. M. Gschwind, M. Armbrüster, I. Z. Zubrzycki, J. Am. Chem. Soc. 2004, 126, 10228-10229.
3. J. A. Castillo-Meléndez, B. T. Golding, Synthesis 2004, 1655-1663.
4. K. Feichtinger, H. L. Sings, T. J. Baker, K. Matthews, M. Goodman, J. Org. Chem. 1998, 63, 8432-8439.
5. M. A. Poss, E. Iwanowicz, J. A. Reid, J. Lin, Z. Gu, Tetrahedron Lett. 1992, 33, 5933-5936.
6. A. Exposito, M. Fernandez-Suarez, T. Iglesias, L. Munoz, R. Riguera, J. Org. Chem. 2001, 66, 4206-4213.
7. Y. F. Yong, J. A. Kowalski, M. A. Lipton, J. Org. Chem. 1997, 62, 1540-1542.
8. B. P. Orner, A. D. Hamilton, J. Inclusion Phenom. Macrocyclic Chem. 2001, 41, 141-147.
9. R. J. Bergeron, J. S. McManis, J. Org. Chem. 1987, 52, 1700-1703.
10. D. R. Kent, W. L. Cody', A. M. Doherty, Tetrahedron Lett. 1996, 37, 8711-8714.
11. B. Lal, A. K. Gangopadhyay, Tetrahedron Lett. 1996, 37, 2483-2486.
12. R. M. Williams, C. Yuan, V. J. Lee, S. Chamberland, J. Antibiot. 1997, 51, 189-201.
13. K. M. Boy, S. Zhu, J. E. Macor, S. Shi, S. Gerritz, N-aryl pyrrolidine derivatives as beta-secretase inhibitors, U. S. P. a. T. Office, United States, 2007.
14. C. O. Manning, A. H. Wadsworth, I. Fellows, J. Labelled Compd. Radiopharm. 2002, 45, 611-618.
15. Y. Zhang, J. Labelled Compd. Radiopharm. 2002, 45, 1055-1064.
16. R. Salter, K. Bordeaux, P. Burtscher, Y. Metz, T. Moenius, I. Rodriguez, R. Ruetsch, R. Voges, C. Zueger, J. Labelled Compd. Radiopharm. 2006, 49, 197-227.
17. T. W. Packham, A. L. Germain, R. Patel, J. R. Barras, D. J. Milne, Organometallic process for preparing 2,3,5-trihalobenzaldehydes, P. I. Appl., United Kingdom, 1995.
18. G. Pattenden, T. Thompson, Chem. Commun. 2001, 8, 717-718.
19. S. Rossiter, C. L. Smith, M. Laki, M. Nandi, H. Gill, J. M. Leiper, P. Vallance, D. L. Selwood, J. Med. Chem. 2005, 48, 4670-4678.
20. J. R. Piper, L. M. Rose, T. P. Johnston, M. M. Grenan, J. Med. Chem. 1979, 22, 631-639.
21. T. Gers, D. Kunce, P. Markowski, J. Izdebski, Synthesis 2004, 1, 37-42.
22. C. Levallet, J. Lerpiniere, S. Y. Ko, Tetrahedron 1997, 53, 5291-5304.