Incidental MRI anomalies suggestive of multiple sclerosis: The radiologically isolated syndrome

Neurology

Volumn 72, Issue 9, 2009, Pages 800-805

  Okuda, D T ^a   Mowry, E M ^a   Beheshtian, A ^a   Waubant, E ^a   Baranzini, S E ^a   Goodin, D S ^a   Hauser, S L ^a   Pelletier, D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; INCIDENTAL FINDING; MALE; MULTIPLE SCLEROSIS; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SURVIVAL; BRAIN; CLASSIFICATION; COHORT ANALYSIS; COMPARATIVE STUDY; DEMYELINATING DISEASE; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PROSPECTIVE STUDY; RADIOGRAPHY; RADIOLOGY; RISK FACTOR; SYNDROME;

ADOLESCENT; ADULT; AGED; BRAIN; COHORT STUDIES; DEMYELINATING DISEASES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; PROSPECTIVE STUDIES; RADIOLOGY; RISK FACTORS; SYNDROME; YOUNG ADULT;

EID: 62849110378     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000335764.14513.1a     Document Type: Article

References (22)

1. Vernooij MW, Ikram MA, Tanghe HL, et al. Incidental findings on brain MRI in the general population. N Engl J Med 2007;357:1821-1828.
2. Kruit MC, vanBuchem MA, Hofman PA, et al. Migraine as a risk factor for subclinical brain lesions. JAMA 2004; 291:427-434.
3. Longstreth WT Jr, Manolio TA, Arnold A, et al. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. Stroke 1996;27:1274-1282.
4. Yue NC, Longstreth WT Jr, Elster AD, et al. Clinically serious abnormalities found incidentally at MR imaging of the brain: data from the Cardiovascular Health Study. Radiology 1997;202:41-46.
5. Brex PA, Ciccarelli O, O'Riordan JI, et al. A longitudinal study of abnormalities on MRI and disability from multiple sclerosis. N Engl J Med 2002;346:199-200.
6. Optic Neuritis Study Group. The 5-year risk of MS after optic neuritis. Experience of the optic neuritis treatment trial. Neurology 1997;49:1404-1413.
7. Barkhof F, Filippi M, Miller DH, et al. Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain 1997;120:2059-2069.
8. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001;50:121-127.
9. Engell T. A clinical patho-anatomical study of clinically silent multiple sclerosis. Acta Neurol Scand 1989;79:428-430.
10. Gilbert JJ, Sadler M. Unsuspected multiple sclerosis. Arch Neurol 1983;40:533-536.
11. Phadke JG, Best PV. Atypical and clinically silent multiple sclerosis: a report of 12 cases discovered unexpectedly at necropsy. J Neurol Neurosurg Psychiatry 1983;46:414-420.
12. Lyoo IK, Seol HY, Byun HS, Renshaw PF. Unsuspected multiple sclerosis in patients with psychiatric disorders: a magnetic resonance imaging study. J Neuropsychiatry Clin Neurosci 1996;8:54-59.
13. Thorpe JW, Mumford CJ, Compston DA, et al. British Isles survey of multiple sclerosis in twins: MRI. J Neurol Neurosurg Psychiatry 1994;57:491-496.
14. De Stefano N, Cocco E, Lai M, et al. Imaging brain damage in first-degree relatives of sporadic and familial multiple sclerosis. Ann Neurol 2006;59:634-639.
15. Sadovnick AD, Yee IM, Ebers GC: Canadian Collaborative Study Group. Factors influencing sib risks for multiple sclerosis. Clin Genet 2000;58:431-435.
16. Lebrun C, Bensa C, Debouverie M, et al. Unexpected multiple sclerosis: follow-up of 30 patients with magnetic resonance imaging and clinical conversion profile. J Neurol Neurosurg Psychiatry 2008;79:195-198.
17. Barkhof F, Held U, Simon J, et al. Predicting gadolinium enhancement status in MS patients eligible for randomized clinical trials. Neurology 2005;65:1447-1454.
18. Kermode AG, Thompson AJ, Tofts P, et al. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Brain 1990;113: 1477-1489.
19. Kappos L, Moeri D, Radue EW, et al. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group. Lancet 1999;353:964-969.
20. Koudriavtseva T, Thompson AJ, Fiorelli M, et al. Gadolinium enhanced MRI predicts clinical and MRI disease activity in relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry 1997;62:285-287.
21. Barkhof F, Filippi M, Miller DH, et al. Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain 1997;120:2059-2069.
22. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983:13:227-231.