Mechanistic studies of permeation enhancers

Percutaneous Penetration Enhancers, Second Edition

Volumn , Issue , 2005, Pages 271-292

  Li, S Kevin ^a   Higuchi, William I ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 62849087409     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (32)

1. Abrams K, Harvell JD, Shriner D, Wertz P, Maibach H, Maibach HI, Rehfeld SJ, Effect of organic solvents on in vitro human skin water barrier function. J Invest Dermatol, 101, 609-613, 1993.
2. Aungst BJ, Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants. Pharm Res, 6, 244-247, 1989.
3. Brain KR, Walters KA, Molecular modeling of skin permeation enhancement by chemical agents. In: Pharmaceutical Skin Penetration Enhancement, Walters KA, Hadgraft J (Eds), 1993, Marcel Dekker, New York. p. 389-416.
4. Chantasart D, Li SK, He N, Warner KS, Prakongpan S, Higuchi WI, Mechanistic studies of branchedchain alkanols as skin permeation enhancers. J Pharm Sci, 93, 762-779, 2004.
5. Golden GM, McKie JE, Potts RO, Role of stratum corneum lipid fluidity in transdermal drug flux. J Pharm Sci, 76, 25-28, 1987.
6. Grubauer G, Feingold KR, Harris RM, Elias PM, Lipid content and lipid type as determinants of the epidermal permeability barrier. J Lipid Res, 30, 89-96, 1989.
7. Hadgraft J, Modulation of the barrier function of the skin. Skin Pharmacol Appl Skin Physiol, 14 Suppl 1, 72-81, 2001.
8. Hadgraft J, Peck J, Williams DG, Pugh J, Allan G, Mechanisms of action of skin penetration enhancers/retarders: azone and analogues. Int J Pharm, 141, 17-25, 1996.
9. He N, Li SK, Suhonen TM, Warner KS, Higuchi WI, Mechanistic study of alkyl azacycloheptanones as skin permeation enhancers by permeation and partition experiments with hairless mouse skin. J Pharm Sci, 92, 297-310, 2003.
10. He N, Warner KS, Chantasart D, Shaker DS, Higuchi WI, Li SK, Mechanistic study of chemical skin permeation enhancers with different polar and lipophilic functional groups. J Pharm Sci, 93, 1415-1430, 2004.
11. He N, Warner KS, Higuchi WI, Li SK, Model analysis of flux enhancement across hairless mouse skin induced by chemical permeation enhancers. Int J Pharm, 297, 9-21, 2005.
12. Kligman AM, Christophers E, Preparation of isolated sheets of human stratum corneum. Arch Dermatol, 88, 702-705, 1963.
13. Kim YH, Ghanem AH, Higuchi WI, Model studies of epidermal permeability. Semin Dermatol, 11, 145-156, 1992.
14. Lambert WJ, Higuchi WI, Knutson K, Krill SL, Effects of long-term hydration leading to the development of polar channels in hairless mouse stratum corneum. J Pharm Sci, 78, 925-928, 1989.
15. Lampe MA, Williams ML, Elias PM, Human epidermal lipids: characterization and modulations during differentiation. J Lipid Res, 24, 131-140, 1983.
16. Lee VHL, Yamamoto A, Kompella UB, Mucosal penetration enhancers for facilitation of peptide and protein drug absorption. Crit Rev Ther Drug Carrier Syst, 8, 91-192, 1991.
17. Li SK, Ghanem A-H, Yoneto K, Higuchi WI, Effects of 1-alkyl-2-pyrrolidones on the lipoidal pathway of human epidermal membrane: a comparison with hairless mouse skin. Pharm Res, 14, S-303, 1997.
18. Liu P, Higuchi WI, Song WQ, Kurihara-Bergstrom T, Good WR, Quantitative evaluation of ethanol effects on diffusion and metabolism of beta-estradiol in hairless mouse skin. Pharm Res, 8, 865-872, 1991.
19. Liu P, Higuchi WI, Ghanem A-H, Kurihara-Bergstrom T, Good WR, Assessing the influence of ethanol in simultaneous diffusion and metabolism of estradiol in hairless mouse skin for the “asymmetric” situation in vitro. Int J Pharm, 78, 123-136, 1992.
20. Nicolaides N, Skin lipids: their biochemical uniqueness. Science, 186, 19-26, 1974.
21. Okamoto H, Hashida M, Sezaki H, Structure-activity relationship of 1-alkyl or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers. J Pharm Sci, 77, 418-424, 1988.
22. Shaker DS, Ghanem AH, Li SK, Warner KS, Hashem FM, Higuchi WI, Mechanistic studies of the effect of hydroxypropyl-beta-cyclodextrin on in vitro transdermal permeation of corticosterone through hairless mouse skin. Int J Pharm, 253, 1-11, 2003.
23. Smith EW, Maibach HI, Percutaneous Penetration Enhancers. 1995, CRC Press, Boca Raton, Florida.
24. Stein W, Transport and Diffusion Across Cell Membranes. 1986, Academic Press, New York.
25. Tanford C, The Hydrophobic Effect: Formation of Micelles and Biological Membranes. 2nd edition. 1980, John Wiley & Sons, New York.
26. Tenjarla SN, Kasina R, Puranajoti P, Omar MS, Harris WT, Synthesis and evaluation of N-acetylprolinate esters -novel skin penetration enhancers. Int J Pharm, 192, 147-158, 1999.
27. Warner KS, Mechanistic Aspects of Chemical Skin Permeation Enhancers, PhD thesis, University of Utah, 2003.
28. Warner KS, Li SK, Higuchi WI, Influences of alkyl group chain length and polar head group on chemical skin permeation enhancement. J Pharm Sci, 90, 1143-1153, 2001.
29. Warner KS, Li SK, He N, Suhonen TM, Chantasart D, Bolikal D, Higuchi WI, Structure-activity relationship for chemical skin permeation enhancers: probing the chemical microenvironment of the site of action. J Pharm Sci, 92, 1305-1322, 2003.
30. Xiang TX, Anderson BD, The relationship between permeant size and permeability in lipid bilayer membranes. J Membr Biol, 140, 111-122, 1994.
31. Yoneto K, Ghanem AH, Higuchi WI, Peck KD, Li SK, Mechanistic studies of the 1-alkyl-2-pyrrolidones as skin permeation enhancers. J Pharm Sci, 84, 312-317, 1995.
32. Yoneto K, Li SK, Higuchi WI, Shimabayashi S, Influence of the permeation enhancers 1-alkyl-2-pyrrolidones on permeant partitioning into the stratum corneum. J Pharm Sci, 87, 209-214, 1998.