A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Ravassard, Philippe ^a   Bricout Neveu, Emilie ^a,b   Hazhouz, Yasmine ^a,b   Pechberty, Severine ^b,c   Mallet, Jacques ^a   Czernichow, Paul ^b   Scharfmann, Raphael ^c  

^a INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^b Endocells   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GLUCOSE; INSULIN; LENTIVIRUS VECTOR; SV40T ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE EXPRESSION PROFILING; GENETIC TRANSDUCTION; IMMUNOCOMPETENCE; INSULIN RELEASE; INSULINOMA; NONHUMAN; PANCREAS ISLET BETA CELL; PROMOTER REGION; RAT; SOMATIC GENE THERAPY; STEM CELL; STEM CELL GENE THERAPY; TRANSGENICS; ANIMAL; CELL LINE; CYTOLOGY; GENE VECTOR; GENETICS; LENTIVIRINAE; METABOLISM; MOUSE; PANCREAS; STEM CELL TRANSPLANTATION; TRANSGENIC MOUSE; TRANSPLANTATION;

MUS; MUS MUSCULUS; RATTUS; RODENTIA;

ANIMALS; CELL LINE; GENETIC VECTORS; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; LENTIVIRUS; MICE; MICE, TRANSGENIC; PANCREAS; PROMOTER REGIONS, GENETIC; RATS; STEM CELL TRANSPLANTATION; STEM CELLS; TRANSDUCTION, GENETIC;

EID: 62749167098     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004731     Document Type: Article

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