Changes in the GST activity of the mussel Mytilus galloprovincialis during exposure and depuration of microcystins

Journal of Experimental Zoology Part A: Ecological Genetics and Physiology

Volumn 311, Issue 3, 2009, Pages 226-230

  Fernandes, Sandra ^a,b   Welker, Martin ^c   Vasconcelos, Vitor Manuel ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c AnagnosTec Gesellschaft fur Analytische Biochemie & Diagnostik mbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; MICROCYSTIN;

ANIMAL; ARTICLE; DRUG DETOXIFICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; GREEN ALGA; METABOLISM; MICROBIOLOGY; MICROCYSTIS; MYTILUS; ULTRAVIOLET SPECTROPHOTOMETRY;

ALGAE, GREEN; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUTATHIONE TRANSFERASE; METABOLIC DETOXICATION, DRUG; MICROCYSTINS; MICROCYSTIS; MYTILUS; SPECTROPHOTOMETRY, ULTRAVIOLET;

ANIMALIA; ANKISTRODESMUS; CHLOROPHYTA; MICROCYSTIS AERUGINOSA; MYTILUS GALLOPROVINCIALIS;

EID: 62749121639     PISSN: 19325223     EISSN: None     Source Type: Journal    
DOI: 10.1002/jez.524     Document Type: Article

References (29)

1. Amorim A, Vasconcelos VM. 1999. Dynamics of microcystins in the mussel. Mytilus galloprovincialis. Toxicon 37:1041-1052.
2. Best JH, Pflugmacher S, Wiegand C, Eddy FB, Metcalf JS, Codd GA. 2002. Effects of enteric bacterial and cyanobacterial lipopolysaccharides, and of microcystin-LR, on glutathione S-transferase activities in zebra fish (Danio rerio). Aquat Toxicol 60:223-231.
3. Cheung CCC, Zheng GJ, Li AMY, Richardson BJ, Lam PKS. 2001. Relationships between tissue concentrations of polycyclic aromatic hydrocarbons and antioxidative responses of marine mussels, Perna viridis. Aquat Toxicol 52:189-203.
4. Cohen P, Holmes CFB, Tsukitani Y. 1990. Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem Sci 15:98-102.
5. Dawson RM. 1998. The toxicology of microcystins. Toxicon 36:953-962.
6. Eriksson JE, Meriluoto JAO, Lindholm T. 1989. Accumulation of a peptide toxin from the cyanobacterium Oscillatoria agardhii in the freshwater mussel Anodonta cygnea. Hydrobiologia 183:211-216.
7. Fastner J, Erhard M, von Döhren H. 2001. Determination of oligopeptide diversity within a single population of Microcystis sp. (cyanobacteria) by typing single colonies by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Appl Environ Microbiol 67:5069-5076.
8. Frasco MF, Guilhermino L. 2002. Effects of dimethoate and beta-naphthoflavone on selected biomarkers of Poecilia reticulata. Fish Physiol Biochem 26:149-156.
9. Garcia C. 2001. Isolamento e toxicologia de estirpes de Microcystis aeruginosa da Lagoa de Mira. MSc thesis, Faculdade de Ciências, Universidade do Porto.
10. Habig W, Pabst MJ, Jacoby WB. 1974. Glutathione-S-transferase: the first step in mercapturic acid formation. J Biol Chem 249:1730-1739.
11. Ibelings BW, Bruning K, de Jorge J, Wolfstein K, Dionisio Pires LM, Postma J, Burger T. 2005. Distribution of microcystins in a lake foodweb: no evidence for biomagnification. Microb Ecol 49:487-500.
12. Kotai J. 1972. Instruction for preparation of modified nutrient solution Z8 for algae. Norwegian Institute for Water Research, Blindem, Oslo, 11/69, 5p.
13. Lima I, Moreira SM, Osten JRV, Soares AMVM, Guilhermino L. 2007. Biochemical responses of the marine mussel Mytilus galloprovincialis to petrochemical environmental contamination along the north-western coast of Portugal. Chemosphere 66:1230-1242.
14. Lindholm T, Eriksson JE, Meriluoto JAO. 1989. Toxic cyanobacteria and water quality problems - examples from a eutrophic lake Åland, South West Finland. Water Res 23:481-486.
15. MacKintosh C, MacKintosh RW. 1994. The inhibition of protein phosphatases by toxins: implications for health and an extremely sensitive and rapid bioassay for toxin detection. In: Codd GA, Jefferies TM, Keevil CW, Potter E, editors. Detection methods for cyanobacterial toxins. Cambridge: The Royal Society of Chemistry. p 90-99.
16. MacKintosh C, Beattie KA, Klumpp S, Cohen P, Codd GA. 1990. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Lett 264:187-192.
17. Metcalf J, Beattie KA, Pflugmacher S, Codd GA. 2000. Immuno- crossreactivity and toxicity assessment of conjugation products of the cyanobacteria toxin microcystin-L. FEMS Microbiol Lett 189:155-158.
18. Pereira P, Dias E, Franca S, Pereira E, Carolino M, Vasconcelos V. 2004. Accumulation and depuration of cyanobacterial paralytic shellfish toxins by the freshwater mussel, Anodonta cygnea. Aquat Toxicol 68:339-350.
19. Pflugmacher S, Wiegand C, Oberemm A, Beattie KA, Krause E, Codd GA, Steinberg CEW. 1998. Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication. Biochim Biophys Acta 1425:527-533.
20. Prepas EE, Kotak BB, Campbell LM, Evans JC, Hrudey SE, Holmes CFB. 1997. Accumulation and elimination of cyanobacterial hepatotoxins by the freshwater clam Anodonta grandis simpsoniana. Can J Fish Aquat Sci 54:41-46.
21. Saker ML, Metcalf JS, Codd GA, Vasconcelos VM. 2004. Accumulation and depuration of the cyanobacterial toxin cylindrospermopsin in the freshwater mussel Anodonta cygnea. Toxicon 43:185-194.
22. Sipiä VO, Kankaanpää HT, Lahti K, Carmichael WW, Meriluoto JAO. 2001. Detection of nodularin in flounders and cod from the Baltic Sea. Environ Toxicol 16:121-126.
23. Vanderploeg HA, Liebig JR, Carmichael WW, Agy MA, Johengen TH, Fahnenstiel GL, Nalepa TF. 2001. Zebra mussel (Dreissena polymorpha) selective filtration promoted toxic Microcystis blooms in Saginaw Bay (Lake Huron) and Lake Erie. Can J Fish Aquat Sci 58:1208-1221.
24. Vasconcelos VM. 1995. Uptake and depuration of the heptapeptide toxin microcystin-LR in Mytilus galloprovincialis. Aquat Toxicol 32:227-237.
25. Vasconcelos VM, Wiegand C, Pflugmacher S. 2007. Dynamics of glutathione-S-transferases in Mytilus galloprovincialis exposed to toxic Microcystis aeruginosa cells, extracts and pure toxins. Toxicon 50:740-745.
26. Watanabe MF, Park HD, Kondo F, Harada K, Hayashi H, Okino T. 1997. Identification and estimation of microcystins in freshwater mussels. Nat Toxins 5:31-35.
27. Williams DE, Dawe SC, Kent ML, Andersen RJ, Craig M, Holmes CFB. 1997. Bioaccumulation and clearance of microcystins from salt water mussels, Mytilus edulis, and in vivo evidence for covalently bound microcystins in mussel tissues. Toxicon 35:1617-1625.
28. Yokoyama A, Park HD. 2002. Depuration kinetics and persistence of the cyanobacterial toxin microcystin-LR in the freshwater bivalve Unio douglasiae. Environ Toxicol 18:61-67.
29. Yoshizawa S, Matsushima R, Watanabe MF, Harada K, Ichihara A, Carmichael WW, Fujiki H. 1990. Inhibition of protein phosphatases by microcystins and nodularin associated with hepatotoxicity. J Cancer Res Clin Oncol 116:609-614.