Homeostatic and hedonic signals interact in the regulation of food intake

Journal of Nutrition

Volumn 139, Issue 3, 2009, Pages 629-632

  Lutter, Michael ^a   Nestler, Eric J ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID; SUGAR;

ADAPTATION; ADDICTION; BULIMIA; CELL FUNCTION; CONFERENCE PAPER; DRUG ABUSE; DRUG EXPOSURE; FEEDING; FOOD INTAKE; HOMEOSTASIS; HUMAN; LIPID DIET; MENTAL STRESS; MOTIVATION; NERVE CELL; NONHUMAN; OBESITY; PALATABILITY; PRADER WILLI SYNDROME; SUGAR INTAKE; DIET; EATING; PHYSIOLOGY; REVIEW;

BULIMIA; DIET; EATING; HOMEOSTASIS; HUMANS;

EID: 62749116046     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.108.097618     Document Type: Conference Paper

References (37)

1. Rogers PJ, Smit HJ. Food craving and food "addiction": a critical review of the evidence from a biopsychosocial perspective. Pharmacol Biochem Behav. 2000;66:3-14.
2. Nestler EJ. Is there a common molecular pathway for addiction? Nat Neurosci. 2005;8:1445-9.
3. Nestler EJ. Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci. 2001;2:119-28.
4. Borgland SL, Taha SA, Sarti F, Fields HL, Bonci A. Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine. Neuron. 2006;49:589-601.
5. Boutrel B, Kenny PJ, Specio SE, Martin-Fardon R, Markou A, Koob GF, de Lecea L. Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. Proc Natl Acad Sei USA. 2005;102: 19168-73.
6. Harris GC, Wimmer M, Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature. 2005;437:556-9.
7. de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA. Food reward in the absence of taste receptor signaling. Neuron. 2008;57:930-41.
8. Zheng H, Patterson LM, Berthoud HR. Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens. J Neurosci. 2007;27:11075-82.
9. Stoeckel LE, Weller RE, Cook EW 3rd, Twieg DB, Knowlton RC, Cox JE. Widespread reward-system activation in obese women in response to pictures of high-calorie foods. Neuroimage. 2008;41:636-47.
10. Russo SJ, Bolanos CA, Theobald DE, DeCarolis NA, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, et al. IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nat Neurosci. 2007;10:93-9.
11. Teegarden SL, Bale TL. Decreases in dietary preference produce increased emotionality and risk for dietary relapse. Biol Psychiatry. 2007;61:1021-9.
12. Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, Impey S, Storm DR, Neve RL, et al. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sei USA. 2002;99:1 1435-40.
13. Olausson P, Jentsch JD, Tronson N, Neve RL, Nestler EJ, Taylor JR. DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. J Neurosci. 2006;26:9196-204.
14. Zigman JM, Elmquist JK. Minireview: From anorexia to obesity-the yin and yang of body weight control. Endocrinology. 2003;144:3749-56.
15. Saper CB, Chou TC, Elmquist JK. The need to feed: homeostatic and hedonic control of eating. Neuron. 2002;36:199-211.
16. Krugel U, Schraft T, Kittner H, Kiess W, Illes P. Basal and feeding-evoked dopamine release in the rat nucleus accumbens is depressed by leptin. Eur J Pharmacol. 2003;482:185-7.
17. Fulton S, Pissios P, Manchon RP, Stiles L, Frank L, Pothos EN, Maratos-Flier E, Flier JS. Leptin regulation of the mesoaccumbens dopamine pathway. Neuron. 2006;51:811-22.
18. Hommel JD, Trinko R, Sears RM, Georgescu D, Liu ZW, Gao XB, Thurmon JJ, Marinelli M, DiLeone RJ. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron. 2006;51:801-10.
19. Farooqi IS, Bullmore E, Keogh J, Gillard J, O'Rahilly S, Fletcher PC. Leptin regulates striatal regions and human eating behavior. Science. 2007;317:1355.
20. Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, et al. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J Clin Invest. 2006; 116: 3229-39.
21. Jerlhag E, Egecioglu E, Dickson SL, Douhan A, Svensson L, Engel JA. Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addict Biol. 2007;12:6-16.
22. Naleid AM, Grace MK, Cummings DE, Levine AS. Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides. 2005;26:2274-9.
23. Malik S, McGlone F, Bedrossian D, Dagher A. Ghrelin modulates brain activity in areas that control appetitive behavior. Cell Metab. 2008;7: 400-9.
24. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edition. Washington, DC: American Psychiatric Association; 1994
25. Simon GE, Von Korff M, Saunders K, Miglioretti DL, Crane PK, van Belle G, Kessler RC. Association between obesity and psychiatric disorders in the US adult population. Arch Gen Psychiatry. 2006;63: 824-30.
26. Lutter M, Sakata I, Osborne-Lawrence S, Rovinsky SA, Anderson JG, Jung S, Birnbaum S, Yanagisawa M, Elmquist JK, et al. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nat Neurosci. 2008;11:752-3.
27. Lutter M, Krishnan V, Russo SJ, Jung S, McClung CA, Nestler EJ. Orexin signaling mediates the antidepressant-like effect of calorie restriction. J Neurosci. 2008;28:3071-5.
28. Lu XY, Kim CS, Frazer A, Zhang W Leptin: a potential novel antidepressant. Proc Natl Acad Sei USA. 2006;103:1593-8.
29. Teegarden SL, Bale TL. Effects of stress on dietary preference and intake are dependent on access and stress sensitivity. Physiol Behav. 2008;93: 713-23.
30. Frank GK, Wagner A, Achenbach S, McConaha C, Skovira K, Aizenstein H, Carter CS, Kaye WH. Altered brain activity in women recovered from bulimic-type eating disorders after a glucose challenge: a pilot study. Int J Eat Disord. 2006;39:76-9.
31. Penas-Lledo EM, Loeb KL, Martin L, Fan J. Anterior cingulate activity in bulimia nervosa: a fMRI case study. Eat Weight Disord. 2007; 12:e78-82.
32. Dimitropoulos A, Schultz RT. Food-related neural circuitry in Prader-Willi syndrome: response to highversus low-calorie foods. J Autism Dev Disord. 2008;38:1642-53.
33. Cummings DE. Ghrelin and the short- and long-term regulation of appetite and body weight. Physiol Behav. 2006;89:71-84.
34. Troisi A, Di Lorenzo G, Lega I, Tesauro M, Bertoli A, Leo R, Iantorno M, Pecchioli C, Rizza S, et al. Plasma ghrelin in anorexia, bulimia, and binge-eating disorder: relations with eating patterns and circulating concentrations of Cortisol and thyroid hormones. Neuroendocrinology. 2005;81:259-66.
35. Corwin RL, Grigson PS. Symposium overview. Food addiction: fact or fiction? J Nutr. 2009;139:617-9.
36. Pelchat ML. Food addiction in humans. J Nutr. 2009;139:620-2.
37. Avena NM, Rada P, Hoebel BG. Sugar and fat bingeing have notable differences in addictive-like behavior. J Nutr. 2009;139: 623-8.