Loss of heterozygosity of TRIM3 in malignant gliomas

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Boulay, Jean Louis ^a   Stiefel, Urs ^b   Taylor, Elisabeth ^a   Dolder, Béatrice ^a   Merlo, Adrian ^a   Hirth, Frank ^b,c  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; TRIPARTITE MOTIF PROTEIN 3; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; TRIM3 PROTEIN, HUMAN;

ARTICLE; CANCER INHIBITION; CHROMOSOME 11P; CHROMOSOME DELETION; CONTROLLED STUDY; GENE DOSAGE; GENE FREQUENCY; GENE FUNCTION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENE TARGETING; GLIOBLASTOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; SINGLE NUCLEOTIDE POLYMORPHISM; BRAIN TUMOR; CHROMOSOME 11; CHROMOSOME MAP; GENETICS; GLIOMA; POLYMERASE CHAIN REACTION; SEQUENCE TAGGED SITE; TUMOR SUPPRESSOR GENE;

BRAIN NEOPLASMS; CARRIER PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; GENE DOSAGE; GENES, TUMOR SUPPRESSOR; GLIOMA; HUMANS; LOSS OF HETEROZYGOSITY; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE TAGGED SITES;

EID: 62649150841     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-71     Document Type: Article

References (44)

1. Merlo A Genes and pathways driving glioblastomas in humans and murine disease models Neurosurg Rev 2003, 26:145-158. 12783270
2. The Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 2008, 455:1061-1068. 18772890
3. Stupp R Hegi ME Gilbert MR Chakravarti A Chemoradiotherapy in malignant glioma: Standard of care and future directions J Clin Oncol 2007, 25:4127-4136. 17827463
4. Al-Hajj M Clarke MF Self-renewal and solid tumor stem cells Oncogene 2004, 23:7274-7282. 15378087
5. Sanai N Alvarez-Buylla A Berger MS Neural stem cells and origin of gliomas N Engl J Med 2005, 353:811-822. 16120861
6. Vescovi AL Galli R Reynolds BA Brain tumor stem cells Nat Rev Cancer 2006, 6:425-236. 16723989
7. Stiles CD Rowitch DH Glioma stem cells: A midterm exam Neuron 2008, 58:832-846. 18579075
8. Singh SK Hawkins C Clarke ID Squire JA Bayani J Hide T Henkelman RM Cusimano MD Dirks PB Identification of human brain tumour initiating cells Nature 2004, 432:396-401. 15549107
9. Taylor MD Poppleton H Fuller C Su X Liu Y Jensen P Magdaleno S Dalton J Calabrese C Board J Macdonald T Rutka J Guha A Gajjar A Curran T Gilbertson RJ Radial glia cells are candidate stem cells of ependymoma Cancer Cell 2005, 8:323-335. 16226707
10. Bao S Wu Q McLendon RE Hao Y Shi Q Hjelmeland AB Dewhirst MW Bigner DD Rich JN Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 2006, 444:756-760. 17051156
11. Arama E Dickman D Kinchie Z Shearn A Lev Z Mutations in the beta-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain Oncogene 2000, 19:3706-3716. 10949924
12. Loop T Leemans R Stiefel U Hermida L Egger B Xie F Primig M Certa U Fischbach KF Reichert H Hirth F Transcriptional signature of an adult brain tumor in Drosophila BMC Genomics 2004, 5:24. 419699 15090076
13. Caussinus E Gonzalez C Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster Nat Genet 2005, 37:1125-1129. 16142234
14. Bello B Reichert H Hirth F The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila Development 2006, 133:2639-2648. 16774999
15. Lee CY Wilkinson BD Siegrist SE Wharton RP Doe CQ Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal Dev Cell 2006, 10:441-449. 16549393
16. Betschinger J Mechtler K Knoblich JA Asymmetric segregation of the tumor suppressor Brat regulates self-renewal in Drosophila neural stem cells Cell 2006, 124:1241-1253. 16564014
17. Beaucher M Goodliffe J Hersperger E Trunova S Frydman H Shearn A Drosophila brain tumor metastases express both neuronal and glial cell type markers Dev Biol 2007, 301:287-297. 1859848 17055475
18. Bowman SK Rolland V Betschinger J Kinsey KA Emery G Knoblich JA The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila Dev Cell 2008, 14:1-12. 18194644
19. Caussinus E Hirth F Asymmetric cell division in development and cancer Prog Mol Subcell Biol 2007, 45:205-225. 17585502
20. Reymond A Meroni G Fantozzi A Merla G Cairo S Luzi L Riganelli D Zanaria E Messali S Cainarca S Guffanti A Minucci S Pelicci PG Ballabio A The tripartite motif family identifies cell compartments EMBO J 2001, 20:2140-2151. 125245 11331580
21. El-Husseini AE Fretier P Vincent SR Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5 Genomics 2001, 71:363-367. 11170753
22. Frosk P Weiler T Nylen E Sudha T Greenberg CR Morgan K Fujiwara TM Wrogemann K Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene Am J Hum Genet 2002, 70:663-672. 447621 11822024
23. Sardiello M Cairo S Fontanella B Ballabio A Meroni G Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties BMC Evol Biol 2008, 8:225. 2533329 18673550
24. Schiebe M Ohneseit P Hoffmann W Meyermann R Rodemann HP Bamberg M Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas J Cancer Res Clin Oncol 2001, 127:325-328. 11355148
25. Scelfo RA Schwienbacher C Veronese A Gramantieri L Bolondi L Querzoli P Nenci I Calin GA Angioni A Barbanti-Brodano G Negrini M Loss of methylation at chromosome 11p15.5 is common in human adult tumors Oncogene 2002, 21:2564-2572. 11971191
26. Lam CT Tang CM Lau KW Lung ML Loss of heterozygosity on chromosome 11 in esophageal squamous cell carcinomas Cancer Lett 2002, 178:75-81. 11849744
27. Larson PS Schlechter BL King CL Yang Q Glass CN Mack C Pistey R de Las Morenas A Rosenberg CL CDKN1C/p57kip2 is a candidate tumor suppressor gene in human breast cancer BMC Cancer 2008, 8:68. 2323395 18325103
28. El-Husseini AE Vincent SR Cloning and characterization of a novel RING finger protein that interacts with class V myosins J Biol Chem 1999, 274:19771-1977. 10391919
29. El-Husseini AE Kwasnicka D Yamada T Hirohashi S Vincent SR BERP, a novel ring finger protein, binds to alpha-actinin-4 Biochem Biophys Res Commun 2000, 267:906-911. 10673389
30. Van Diepen MT Spencer GE van Minnen J Gouwenberg Y Bouwman J Smit AB van Kesteren RE The molluscan RING-finger protein L-TRIM is essential for neuronal outgrowth Mol Cell Neurosci 2005, 29:74-81. 15866048
31. Kleihues P Louis DN Scheithauer BW Rorke LB Reifenberger G Burger PC Cavenee WK The WHO classification of tumors of the nervous system J Neuropathol Exp Neurol 2002, 61:215-225. 11895036
32. Maier D Comparone D Taylor E Zhang Z Gratzl O Van Meir EG Scott RJ Merlo A New deletion in low-grade oligodendroglioma at the glioblastoma suppressor locus on chromosome 10q25-26 Oncogene 1997, 15:997-1000. 9285695
33. Maier D Zhang Z Taylor E Hamou MF Gratzl O Van Meir EG Scott RJ Merlo A Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/ MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas Oncogene 1998, 16:3331-3335. 9681833
34. Labuhn M Jones G Speel EJ Maier D Zweifel C Gratzl O Van Meir EG Hegi ME Merlo A Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas Oncogene 2001, 20:1103-1109. 11314047
35. Sonoda Y Iizuka M Yasuda J Makino R Ono T Kayama T Yoshimoto T Sekiya T Loss of heterozygosity at 11p15 in malignant glioma Cancer Res 1995, 55:2166-2168. 7743518
36. Campuzano S Modolell J Patterning of the Drosophila nervous system: The achaete-scute gene complex Trends Genet 1992, 8:202-208. 1496555
37. Cairns P Tokino K Eby Y Sidransky D Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction Cancer Res 1994, 54:1422-1424. 8137242
38. Ohgaki H Kleihues P Genetic pathways to primary and secondary glioblastoma Am J Pathol 2007, 170:1445-1453. 1854940 17456751
39. Baffa R Negrini M Mandes B Rugge M Ranzani GN Hirohashi S Croce CM Loss of heterozygosity for chromosome 11 in adenocarcinoma of the stomach Cancer Res 1996, 56:268-272. 8542579
40. Fults D Petronio J Noblett BD Pedone CA Chromosome 11p15 deletions in human malignant astrocytomas and primitive neuroectodermal tumors Genomics 1992, 14:799-801. 1358812
41. Hoffmann MJ Florl AR Seifert HH Schulz WA Multiple mechanisms downregulate CDKN1C in human bladder cancer Int J Cancer 2005, 114:406-413. 15551363
42. Lu KH Weitzel JN Kodali S Welch WR Berkowitz RS Mok SC A novel 4-cM minimally deleted region on chromosome 11p15.1 associated with high grade nonmucinous epithelial ovarian carcinomas Cancer Res 1997, 57:387-90. 9012461
43. Nakata T Yoshimoto M Kasumi F Akiyama F Sakamoto G Nakamura Y Emi M Identification of a new commonly deleted region within a 2-cM interval of chromosome 11p11 in breast cancers Eur J Cancer 1998, 34:417-421. 9640233
44. Zhao B Bepler G Transcript map and complete genomic sequence for the 310 kb region of minimal allele loss on chromosome segment 11p15.5 in non-small-cell lung cancer Oncogene 2001, 20:8154-8164. 11781830