Therapeutic hypothermia: The safar vision

Journal of Neurotrauma

Volumn 26, Issue 3, 2009, Pages 417-420

  Kochanek, Patrick M ^a,b   Drabek, Tomas ^a,b   Tisherman, Samuel A ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebrospinal fluid; Clinical trial; Glia cell response to injury; Human studies; Hypothermia; Pediatric brain injury; Regeneration; Stem cells; Therapeutic approaches for the treatment of CNS injury; Traumatic brain injury; Traumatic spinal cord injury

Indexed keywords

BRAIN TEMPERATURE; CENTRAL NERVOUS SYSTEM; HEART ARREST; HUMAN; INDUCED HYPOTHERMIA; INTENSIVE CARE; INTRACRANIAL PRESSURE; NEUROPROTECTION; RESUSCITATION; REVIEW; SPINAL CORD INJURY; STROKE; TRAUMATIC BRAIN INJURY;

BRAIN; BRAIN INJURIES; HEART ARREST; HISTORY, 20TH CENTURY; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; NERVE REGENERATION; RECOVERY OF FUNCTION; RESUSCITATION;

EID: 62649132891     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2008.0612     Document Type: Review

References (37)

1. Albin, M.S., White, R.J., and Locke, G.E. (1965). Treatment of spinal cord trauma by selective hypothermic perfusion. Surg. Forum 16, 423-424.
2. Behringer, W., Prueckner, S., Kentner, R., Tisherman, S.A., Radvosky, A., Clark, R., Stezoski, S.W., Henchir, J., Klein, E., and Safar, P. (2000). Rapid hypothermic aortic flush can achieve survival without brain damage after 30 minutes cardiac arrest in dogs. Anesthesiology 93, 1491-1499.
3. Behringer, W., Safar, P., Wu, X., Kentner, R., Radovsky, A., Kochanek, P.M., Dixon, C.E., and Tisherman, S.A. (2003). Survival without brain damage after clinical death of 60-120 mins of dogs using suspended animation by profound hypothermia. Crit. Care Med. 31, 1523-1531.
4. Conn, A.W., Edmonds, J.F., and Barker, G.A. (1979). Cerebral resuscitation in near-drowning. Pediatr. Clin. North Am. 26, 691-701.
5. Crippen, D., Safar, P., Porter, L., and Zona, J. (1991). Improved survival of hemorrhagic shock with oxygen and hypothermia in rats. Resuscitation 21, 271-281.
6. Drabek, T., Stezoski, J., Garman, R.H., Wu, X., Tisherman, S.A., Stezoski, S.W., Fisk, J.A., Jenkins, L., and Kochanek, P.M. (2007). Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: a feasibility trial. Crit. Care Med. 35, 532-537.
7. Gisvold, S.E., Safar, P., Rao, G., Moossy, J., Kelsey, S., and Alexander, H. (1984). Multifaceted therapy after global brain ischemia in monkeys. Stroke 15, 803-812.
8. Haque, I.U., Latour, M.C., and Zaritsky, A.L. (2006). Pediatric critical care community survey of knowledge and attitudes toward therapeutic hypothermia in comatose children after cardiac arrest. Pediatr. Crit. Care Med. 7:7-14.
9. Hypothermia After Cardiac Arrest Study Group. (2002). Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N. Engl. J. Med. 346, 549-556.
10. Kochanek, P.M., and Safar, P.J. (2003). Therapeutic hypothermia for severe traumatic brain injury. JAMA 289, 3007-3009.
11. Kuboyama, K., Safar, P., Radovsky, A., Tisherman, S.A., Stezoski, S.W., and Alexander, H. (1993). Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: a prospective, randomized study. Crit. Care Med. 21, 1348-1358.
12. Larrey, D.J. (1814). Memoirs of Military Surgery and Campaigns of the French Armies. Translated by Richard Wilmott Hall. Volume I. Joseph Cushing/University Press of Sergeant Hall: Baltimore.
13. Leonov, Y., Sterz, F., Safar, P., Radovsky, A., Oku, K., Tisherman, S., and Stezoski, S.W. (1990). Mild cerebral hypothermia during and after cardiac arrest improves neurologic outcome in dogs. J. Cereb. Blood Flow Metab. 10, 57-70.
14. Lundberg, N., Troupp, H., and Lorin, H. (1965). Continuous recording of the ventricular-fluid pressure in patients with severe acute traumatic brain injury: a preliminary report. J. Neurosurg. 22, 581-590.
15. Nozari, A., Safar, P., Stezoski, S.W., Wu, X., Henchir, J., Radovsky, A., Hanson, K., Klein, E., Kochanek, P.M., and Tisherman, S.A. (2004). Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs. Crit. Care Med. 32, 2110-2116.
16. Nozari, A., Safar, P., Stezoski, S.W., Wu, X., Kostelnik, S., Radovsky, A., Tisherman, S.A., and Kochanek, P.M. (2006). Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation. Circulation 113, 2690-2696.
17. Phelps, C. (1897). Traumatic injuries of the brain and its membranes, in: The Classics of Neurology and Neurosurgery Library. D. Appleton and Company: New York, pps. 223-224.
18. Prueckner, S., Safar, P., Kentner, R., Stezoski, J., and Tisherman, S.A. (2001). Mild hypothermia increases survival from severe pressure-controlled hemorrhagic shock in rats. J. Trauma 50, 253-262.
19. Reich, H., Angelos, M., Safar, P., Sterz, F., and Leonov, Y. (1990). Cardiac resuscitability with cardiopulmonary bypass after increasing ventricular fibrillation times in dogs. Ann. Emerg. Med. 19, 887-890.
20. Rosomoff, H.L., and Gilbert, R. (1955). Brain volume and cerebrospinal fluid pressure during hypothermia. Am. J. Physiol. 183, 19.
21. Rosomoff, H.L., and Safar, P. (1965). Management of the comatose patient, in: Respiratory Therapy. P. Safar (ed), F.A. Davis Co.: Philadelphia, pps. 244-258.
22. Safar, P. (1964). Community-wide cardiopulmonary resuscitation. J. Iowa Med. Soc. 629-635.
23. Safar, P. (2003). Mild hypothermia in resuscitation: a historical perspective. Ann. Emerg. Med. 41, 887-888.
24. Safar, P., Bleyaert, A., Nemoto, E.M., Moossy, J., and Snyder, J.V. (1978). Resuscitation after global brain ischemia-anoxia. Crit. Care Med. 6, 215-227.
25. Safar, P.J., and Kochanek, P.M. (2002). Therapeutic hypothermia after cardiac arrest. N. Engl. J. Med. 346, 612-613.
26. Takasu, A., Stezoski, S.W., Stezoski, J., Safar, P., and Tisherman, S.A. (2000). Mild or moderate hypothermia, but not increased oxygen breathing, increases long-term survival after uncontrolled hemorrhagic shock in rats. Crit. CareMed. 28, 2465-2474.
27. Tisherman, S.A., Rodriguez, A., and Safar, P. (1999). Therapeutic hypothermia in traumatology. Surg. Clin. North Am. 79, 1269-1289.
28. Tisherman, S.A., Safar, P., Radovsky, A., Peitzman, A., Marrone, G., Kuboyama, K., and Weinrauch, V. (1991). Profound hypothermia (less than 10°C) compared with deep hypothermia (15°C) improves neurologic outcome in dogs after two hours' circulatory arrest induced to enable resuscitative surgery. J. Trauma 31, 1051-1061.
29. Tisherman, S.A., Safar, P., Radovsky, A., Peitzman, A., Sterz, F., and Kuboyama, K. (1990). Therapeutic deep hypothermic circulatory arrest in dogs: a resuscitation modality for hemorrhagic shock with "irreparable" injury. J. Trauma 30, 836-847.
30. Tortorici, M.A., Kochanek, P.M., Bies, R.R., and Poloyac, S.M. (2006). Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model. Crit. Care Med. 34, 785-791.
31. Tortorici, M.A., Kochanek, P.M., and Poloyac, S.M. (2007). Effects of hypothermia on drug disposition, metabolism, and response: a focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Crit.CareMed. 35, 2196-2204.
32. Wang, H.E., Callaway, C.W., Peitzman, A.B., and Tisherman, S.A. (2005). Admission hypothermia and outcome after major trauma. Crit. Care Med. 33, 1296-1301.
33. Williams, G.R., Jr., and Spencer, F.C. (1958). The clinical use of hypothermia following cardiac arrest. Ann. Surg. 148, 462-468.
34. Wu, X., Drabek, T., Kochanek, P.M., Henchir, J., Stezoski, S.W., Stezoski, J., Cochran, K., Garman, R., and Tisherman, S.A. (2006). Induction of profound hypothermia for emergency preservation and resuscitation allows intact survival after cardiac arrest resulting from prolonged lethal hemorrhage and trauma in dogs. Circulation 25, 1974-1982.
35. Wu, X., Drabek, T., Tisherman, S.A., Henchir, J., Stezoski, S.W., Culver, S., Stezoski, J., Jackson, E.K., Garman, R., and Kochanek, P.M. (2008). Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguinations in dogs. J. Cereb. Blood Flow Metab. 28, 302-311.
36. Wu, X., Stezoski, J., Safar, P., Behringer, W., Kentner, R., Kochanek, P.M., and Tisherman, S.A. (2002). Systemic hypothermia, but not regional gut hypothermia, improves survival from prolonged hemorrhagic shock in rats. J. Trauma 53, 654-662.
37. Yu, C.G., Jimenez, O., Marcillo, A.E., Weider, B., Bangerter, K., Dietrich, W.D., Castro, S., and Yezierski, R.P. (2000). Beneficial effects of modest systemic hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats. J. Neurosurg. 93, 85-93.