메뉴 건너뛰기




Volumn 4, Issue 1, 2009, Pages

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN F; PROTEIN HBS1L; PROTEIN HMIP 2; PROTEIN MYB; SPACER DNA; UNCLASSIFIED DRUG;

EID: 62649123871     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004218     Document Type: Article
Times cited : (68)

References (16)
  • 1
    • 0016793039 scopus 로고
    • Fetal hemoglobin restriction to a few erythrocytes (F cells) in normal human adults
    • Boyer SH, Belding TK, Margolet L, Noyes AN (1975) Fetal hemoglobin restriction to a few erythrocytes (F cells) in normal human adults. Science 188: 361-363.
    • (1975) Science , vol.188 , pp. 361-363
    • Boyer, S.H.1    Belding, T.K.2    Margolet, L.3    Noyes, A.N.4
  • 2
    • 0033966370 scopus 로고    scopus 로고
    • Genetic influences on F cells and other hematologic variables: A twin heritability study
    • Garner C, Tatu T, Reittie JE, Littlewood T, Darley J, et al. (2000) Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood 95: 342-346.
    • (2000) Blood , vol.95 , pp. 342-346
    • Garner, C.1    Tatu, T.2    Reittie, J.E.3    Littlewood, T.4    Darley, J.5
  • 3
    • 0008445052 scopus 로고    scopus 로고
    • A candidate gene study of F cell levels in sibling pairs using a joint linkage and association analysis
    • Garner C, Tatu T, Game L, Cardon LR, Spector TD, et al. (2000) A candidate gene study of F cell levels in sibling pairs using a joint linkage and association analysis. GeneScreen 1: 9-14.
    • (2000) GeneScreen , vol.1 , pp. 9-14
    • Garner, C.1    Tatu, T.2    Game, L.3    Cardon, L.R.4    Spector, T.D.5
  • 4
    • 34547450531 scopus 로고    scopus 로고
    • Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults
    • Thein SL, Menzel S, Peng X, Best S, Jiang J, et al. (2007) Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults. Proc Natl Acad Sci U S A 104: 11346-11351.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11346-11351
    • Thein, S.L.1    Menzel, S.2    Peng, X.3    Best, S.4    Jiang, J.5
  • 5
    • 34748864128 scopus 로고    scopus 로고
    • A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15
    • Menzel S, Garner C, Gut I, Matsuda F, Yamaguchi M, et al. (2007) A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15. Nat Genet 39: 1197-1199.
    • (2007) Nat Genet , vol.39 , pp. 1197-1199
    • Menzel, S.1    Garner, C.2    Gut, I.3    Matsuda, F.4    Yamaguchi, M.5
  • 6
    • 40349092939 scopus 로고    scopus 로고
    • Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia
    • Uda M, Galanello R, Sanna S, Lettre G, Sankaran VG, et al. (2008) Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proc Natl Acad Sci U S A 105: 1620-1625.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 1620-1625
    • Uda, M.1    Galanello, R.2    Sanna, S.3    Lettre, G.4    Sankaran, V.G.5
  • 7
    • 64149105260 scopus 로고    scopus 로고
    • Ethnic differences in F cell levels may be an important tool in the search for genetic loci controlling fetal haemoglobin
    • In Press
    • Creary LE, McKenzie CA, Menzel S, Hanchard NA, Taylor V, et al. (2008) Ethnic differences in F cell levels may be an important tool in the search for genetic loci controlling fetal haemoglobin. British Journal of Haematology In Press.
    • (2008) British Journal of Haematology
    • Creary, L.E.1    McKenzie, C.A.2    Menzel, S.3    Hanchard, N.A.4    Taylor, V.5
  • 10
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 11
    • 13844270527 scopus 로고    scopus 로고
    • Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation
    • Stephens M, Scheet P (2005) Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet 76: 449-462.
    • (2005) Am J Hum Genet , vol.76 , pp. 449-462
    • Stephens, M.1    Scheet, P.2
  • 12
    • 1842435261 scopus 로고    scopus 로고
    • Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations
    • Crawford DC, Carlson CS, Rieder MJ, Carrington DP, Yi Q, et al. (2004) Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet 74: 610-622.
    • (2004) Am J Hum Genet , vol.74 , pp. 610-622
    • Crawford, D.C.1    Carlson, C.S.2    Rieder, M.J.3    Carrington, D.P.4    Yi, Q.5
  • 13
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, et al. (2007) A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851-861.
    • (2007) Nature , vol.449 , pp. 851-861
    • Frazer, K.A.1    Ballinger, D.G.2    Cox, D.R.3    Hinds, D.A.4    Stuve, L.L.5
  • 14
    • 50149117726 scopus 로고    scopus 로고
    • DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
    • Lettre G, Sankaran VG, Bezerra MA, Araujo AS, Uda M, et al. (2008) DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Proc Natl Acad Sci U S A 105: 11869-11874.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11869-11874
    • Lettre, G.1    Sankaran, V.G.2    Bezerra, M.A.3    Araujo, A.S.4    Uda, M.5
  • 15
    • 0036323319 scopus 로고    scopus 로고
    • Genetic analysis of African populations: Human evolution and complex disease
    • Tishkoff SA, Williams SM (2002) Genetic analysis of African populations: human evolution and complex disease. Nat Rev Genet 3: 611-621.
    • (2002) Nat Rev Genet , vol.3 , pp. 611-621
    • Tishkoff, S.A.1    Williams, S.M.2
  • 16
    • 0035337657 scopus 로고    scopus 로고
    • Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE)
    • McKenzie CA, Abecasis GR, Keavney B, Forrester T, Ratcliffe PJ, et al. (2001) Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE). Hum Mol Genet 10: 1077-1084.
    • (2001) Hum Mol Genet , vol.10 , pp. 1077-1084
    • McKenzie, C.A.1    Abecasis, G.R.2    Keavney, B.3    Forrester, T.4    Ratcliffe, P.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.