Hyperhomocysteinemia and bone mineral density: A case - control study

Pakistan Journal of Medical Sciences

Volumn 25, Issue 1, 2009, Pages 91-96

  Mobasseri, Majid ^a   Aliasgharzadeh, Akbar ^a,b   Ebrahimzadeh, Zinolabedin ^a   Najafipoor, Farzad ^a   Niafar, Mitra ^a   Aghamohammadzadeh, Naser ^a   Bahrami, Amir ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Endocrine and Metabolism Section   (Iran)

Author keywords

Bone mineral density; Homocysteine; Osteoporosis

Indexed keywords

HOMOCYSTEINE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; BONE DENSITOMETRY; BONE DENSITY; CASE CONTROL STUDY; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME IMMUNOASSAY; FEMALE; FEMUR NECK; FRACTURE; GROUPS BY AGE; HUMAN; HYPERHOMOCYSTEINEMIA; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; OSTEOPOROSIS; RISK FACTOR;

EID: 62549163867     PISSN: 1682024X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Iqbal MM. Osteoporosis: epidemiology, diagnosis, and treatment. South Med J 2000;93(1):2-18.
2. Heinemann DF. Osteoporosis, An overview of the National Osteoporosis Foundation clinical practice guide. Geriatrics 2000;55(5):31-6.
3. Fikelstein JD, Martin JJ. Homocysteine. Int J Biochem Cell Biol 2000;32(4):385-9.
4. McLean RR, Jacques PF, Selhub J. Homocysteine as a Predictive Factor for Hip Fracture in Older Persons. N Engl J Med 2004;350:2042-9.
5. McKusick VA. Heritable disorders of connective tissue. Mosby 1966;1:155.
6. Jackson SH. The reaction of homocysteine with aldehyde: an explanation of the collagen defects in homocystinuria. Clin Chim Acta 1973;45:215-7.
7. Lubec B, Fang- Kircher S, Lubec T, Blom HJ, Boers GH. Evidence for McKusick's hypothesis of deficient collagen cross-linking in patients with homocystinuria. Biochim Biophys Acta 1996;1315:159-162.
8. Masse PG, Boskey AL, Ziv I. Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model. BMC Musculoskelet Disord 2003;4:2.
9. Carmel R, Green R, Rosenblatt DS, Watkins D. Update on Cobalamin, Folate, and Homocysteine. American Society of Hematology 2003;1:62-81.
10. Raisz LG. Homocysteine and Osteoporotic Fractures - Culprit or Bystander? N Engl J Med 2004;350:20.
11. Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 1994;9:1137-41.
12. Fakhrzadeh H, Ghotbi S, Pourebrahim R, Nouri M, Heshmat R, Bandarian F, et al. Total plasma homocysteine, folate, and vitamin b12 status in healthy Iranian adults: the Tehran homocysteine survey (2003-2004)/a cross - sectional population based study. BMC Public Health 2006;6:29.
13. Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of in creasing folic acid intakes. JAMA 1995;274:1049-57.
14. Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L. Folate, vitamin B12 and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998;55:1449-55.
15. Seshadri S, Beiser A, Selhub J. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002;346:476-783.
16. Van Meurs JB, Dhonukshe - Rutten R. Homocysteine levels and the Risk of Osteoporotic Fracture. N Engl J Med 2004;350:2033-41.
17. Orris MS, Jacques PF, Selhub J. Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. Bone 2005;37:234-42.
18. Mudd SH, Skovby F, Levy HL, Pettigrew KD, Wilcken B. The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet 1985;37:1-31.
19. Herrmann M, Widmann T, Herrmann W. Homocysteine-a newly recognized risk factor for osteoporosis. Clin Chem Lab Med 2005;43(10):1111-7.
20. Janson M. Supplements and Osteoporosis. Healthy Living 2004;6(6):2.
21. Dhonukshe-Rutten RA, Lips M, de Jong N, Chin A Paw MJ, Hiddink GJ, van Dusseldorp M, et al. Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men. J Nutr 2003;133(3):801-7.
22. Sato Y, Hondaa Y, Iwamotob J, Kanokoc T, Satohd K. Homocysteine as a predictive factor for hip fracture in stroke patients. Bone 2005;36:721-6.
23. Cagnacci A, Baldassari F, Rivolta G. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women. Bone 2003;33:956-9.
24. Browner WS, Malinow MR. Hemocysteinemia and bone density in elderly women. Lancet 1991;338:1470.
25. Villadsen MM, Bunger MH, Castens M, Stenkjaer L, Langdahl BL. Methylene tetrahydrofolate reductase (MTHFR) C667T polymorphism is associated with osteoporotic vertebral fractures, but is a weak predictor of BMD. Osteoporos Int 2005;16(4):411-6.
26. Stone KL, Bauer DC, Sellmeyer D, Cummings SR. Low serum vitamin B12 levels are associate d with increased hip bone loss in older women: a prospective study. J Clin Endocrinol Metab 2004;89:1217-21.
27. Golbahar J, Hamidi A, Amin zadeh MA, Omrani GR. Association of plasma folate, plasma total homocysteine, but not methylene tetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: A cross-sectional study. Bone 2004;35:760-5.