Immunohistochemical localization of oestrogen receptors α and β, progesterone receptor and aromatase in the equine placenta

Reproduction in Domestic Animals

Volumn 44, Issue 2, 2009, Pages 312-319

  Abd Elnaeim, M M M ^b   Derar, I R ^b   Wilsher, S ^c   Allen, W R ^c   Leiser, R ^a   Schuler, G ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b Assiut University   (Egypt)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GESTAGEN; PROGESTERONE RECEPTOR;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMISTRY; CHORION VILLUS; FEMALE; GESTATIONAL AGE; HORSE; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; PHYSIOLOGY; PLACENTA; PREGNANCY; TROPHOBLAST; VASCULARIZATION;

ANIMALS; AROMATASE; CHORIONIC VILLI; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; FEMALE; GESTATIONAL AGE; HORSES; IMMUNOHISTOCHEMISTRY; MALE; PLACENTA; PREGNANCY; PROGESTINS; RECEPTORS, PROGESTERONE; TROPHOBLASTS;

EQUIDAE;

EID: 62549163393     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2008.01073.x     Document Type: Article

References (54)

1. Abbondanza C, de Falco A, Nigro V, Medici N, Armetta I, Molinari AM, Moncharmont B, Puca GA, 1993 : Characterization and epitope mapping of a new panel of monoclonal antibodies to estradiol receptor. Steroids 58, 4 12.
2. Abd-Elnaeim MM, Leiser R, Wilsher S, Allen WR, 2006 : Structural and haemovascular aspects of placental growth throughout gestation in young and aged mares. Placenta 27, 1103 1113.
3. Allen WR, 2001a : Fetomaternal interactions and influences during equine pregnancy. Reproduction 121, 513 527.
4. Allen WR, 2001b : Luteal deficiency and embryo mortality in the mare. Reprod Domest Anim 36, 121 131.
5. Allen WR, Stewart F, 2001 : Equine placentation. Reprod Fertil Dev 13, 623 634.
6. Arai KY, Tanaka Y, Taniyama H, Tsunoda N, Nambo Y, Nagamine N, Watanabe G, Taya K, 2006 : Expression of inhibins, activins, insulin-like growth factor-I and steroidogenic enzymes in the equine placenta. Domest Anim Endocrinol 31, 19 34.
7. 3H] equilin in the pregnant mare. Endocrinology 108, 232 238.
8. Bukovsky A, Cekanova M, Caudle MR, Wimalasena J, Foster JS, Henley DC, Elder RF, 2003a : Expression and localization of estrogen receptor-alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradiol. Reprod Biol Endocrinol 1, 13.
9. Bukovsky A, Caudle MR, Cekanova M, Fernando RI, Wimalasena J, Foster JS, Henley DC, Elder RF, 2003b : Placental expression of estrogen receptor beta and its hormone binding variant - comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells. Reprod Biol Endocrinol 1, 36.
10. Cox JE, 1975 : Oestrone and equilin in the plasma of the pregnant mare. J Reprod Fertil Suppl 23, 463 468.
11. Diczfalusy E, 1964 : Endocrine functions of the human fetoplacental unit. Fed Proc 23, 791 798.
12. Diczfalusy E, 1969 : Steroid metabolism in the human foeto-placental unit. Acta Endocrinol (Copenh) 61, 649 664.
13. Enders AC, Carter AM, 2006 : Comparative placentation: some interesting modifications for histotrophic nutrition - a review. Placenta 27 Suppl A, 11 16.
14. Gerstenberg C, Allen WR, Stewart F, 1999 : Cell proliferation patterns during development of the equine placenta. J Reprod Fertil 117, 143 152.
15. Han X, Rossdale PD, Ousey J, Holdstock N, Allen WR, Silver M, Fowden AL, McGladdery AJ, Labrie F, Belanger A, Ensor CM, Tai H-H, Challis JRG, 1995 : Localisation of 15-hydroxy prostaglandin dehydrogenase (PGDH) and steroidogenic enzymes in the equine placenta. Equine Vet J 27, 334 339.
16. Hoffmann B, Höveler R, Nohr B, Hasan SH, 1994 : Investigations on hormonal changes around parturition in the dog and the occurrence of pregnancy-specific non conjugated oestrogens. Exp Clin Endocrinol 102, 185 189.
17. Hoffmann B, Gentz F, Failing K, 1996 : Investigations into the course of progesterone-, oestrogen and eCG concentrations during normal and impaired pregnancy in the mare. Reprod Domest Anim 31, 717 723.
18. Holtan DW, Squires EL, Lapin DR, Ginther OJ, 1979 : Effect of ovariectomy on pregnancy in mares. J Reprod Fertil Suppl 27, 457 463.
19. Holtan DW, Houghton E, Silver M, Fowden AL, Ousey J, Rossdale PD, 1991 : Plasma progestagens in the mare, fetus and newborn foal. J Reprod Fertil Suppl 44, 517 528.
20. Jang S, Yi LS, 2005 : Identification of a 71 kDa protein as a putative non-genomic membrane progesterone receptor in boar spermatozoa. J Endocrinol 184, 417 425.
21. Juengel JL, Heath DA, Quirke LD, McNatty KP, 2006 : Oestrogen receptor alpha and beta, androgen receptor and progesterone receptor mRNA and protein localisation within the developing ovary and in small growing follicles of sheep. Reproduction 131, 81 92.
22. Karteris E, Zervou S, Pang Y, Dong J, Hillhouse EW, Randeva HS, Thomas P, 2006 : Progesterone signaling in human myometrium through two novel membrane G protein-coupled receptors: potential role in functional progesterone withdrawal at term. Mol Endocrinol 20, 1519 1534.
23. Lange CA, 2007 : Editorial: membrane and nuclear steroid hormone receptors: two integrated arms of the same signaling pathway? Steroids 72, 105 106.
24. Leiser R, Kaufmann P, 1994 : Placental structure: in a comparative aspect. Exp Clin Endocrinol 102, 122 134.
25. Lessey BA, Killam AP, Metzger DA, Haney AF, Greene GL, McCarty KS, 1988 : Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. J Clin Endocrinol Metab 67, 334 340.
26. Luconi M, Bonaccorsi L, Maggi M, Pecchioli P, Krausz C, Forti G, Baldi E, 1998 : Identification and characterization of functional nongenomic progesterone receptors on human sperm membrane. J Clin Endocrinol Metab 83, 877 885.
27. Mason JI, France JT, Magness RR, Murry BA, Rosenfeld CR, 1989 : Ovine placental steroid 17 alpha-hydroxylase/C-17,20-lyase, aromatase and sulphatase in dexamethasone-induced and natural parturition. J Endocrinol 122, 351 359.
28. Möstl E, 1994 : The horse feto-placental unit. Exp Clin Endocrinol 102, 166 168.
29. Mutembei HM, Pesch S, Schuler G, Hoffmann B, 2005 : Expression of oestrogen receptors alpha and beta and of aromatase in the testis of immature and mature boars. Reprod Domest Anim 40, 228 236.
30. Nett TM, Holtan DW, Estergreen VL, 1975 : Oestrogens, LH, PMSG, and prolactin in serum of pregnant mares. J Reprod Fertil Suppl 23, 457 462.
31. Numazawa M, Osawa Y, 1987 : Equilin and equilenin biosynthesis. Stereochemistry of aromatization of 3-hydroxy-3,5,7-androstatrien-17-one by horse placenta. J Steroid Biochem 26, 137 143.
32. Ousey JC, Forhead AJ, Rossdale PD, Grainger L, Houghton E, Fowden AL, 2003 : Ontogeny of uteroplacental progestagen production in pregnant mares during the second half of gestation. Biol Reprod 69, 540 548.
33. Ousey JC, Houghton E, Grainger L, Rossdale PD, Fowden AL, 2005 : Progestagen profiles during the last trimester of gestation in Thoroughbred mares with normal or compromised pregnancies. Theriogenology 63, 1844 1856.
34. Pashen RL, Allen WR, 1979 : The role of the fetal gonads and placenta in steroid production, maintenance of pregnancy and parturition in the mare. J Reprod Fertil Suppl 27, 499 509.
35. Pashen RL, Sheldrick EL, Allen WR, Flint AP, 1982 : Dehydroepiandrosterone synthesis by the fetal foal and its importance as an oestrogen precursor. J Reprod Fertil Suppl 32, 389 397.
36. Pepe GJ, Albrecht ED, 1995 : Actions of placental and fetal adrenal steroid hormones in primate pregnancy. Endocr Rev 16, 608 648.
37. Raeside JI, Liptrap RM, 1975 : Patterns of urinary oestrogen excretion in individual pregnant mares. J Reprod Fertil Suppl 23, 649 675.
38. Raeside JI, Renaud RL, 1985 : Identification of 3 beta-hydroxy-5,7- androstadien-17-one as a secretory product of the fetal horse gonad in vivo and in vitro. J Endocrinol 107, 415 419.
39. Raeside JI, Renaud RL, Christie HL, 1997 : Postnatal decline in gonadal secretion of dehydroepiandrosterone and 3 beta-hydroxyandrosta-5,7-dien-17-one in the newborn foal. J Endocrinol 155, 277 282.
40. Rance TA, Park BK, 1978 : The measurement of oestrone, equilin and dehydroepiandrosterone in the peripheral plasma of pregnant pony mares by radioimmunoassay. J Steroid Biochem 9, 1065 1069.
41. Rossdale PD, McGladdery AJ, Ousey JC, Holdstock N, Grainger L, Houghton E, 1992 : Increase in plasma progestagen concentrations in the mare after foetal injection with CRH, ACTH or betamethasone in late gestation. Equine Vet J 24, 347 350.
42. Samuel CA, Allen WR, Steven DH, 1975 : Ultrastructural development of the equine placenta. J Reprod Fertil Suppl 23, 575 578.
43. Samuel CA, Allen WR, Steven DH, 1976 : Studies on the equine placenta II. Ultrastructure of the placental barrier. J Reprod Fertil 48, 257 264.
44. Schuler G, Hartung F, Hoffmann B, 1994 : Investigations on the use of C-21-steroids as precursors for placental oestrogen synthesis in the cow. Exp Clin Endocrinol 102, 169 174.
45. Schuler G, Wirth C, Klisch K, Pfarrer C, Leiser R, Hoffmann B, 1999 : Immunolocalization of progesterone receptors in bovine placentomes throughout mid and late gestation and at parturition. Biol Reprod 61, 797 801.
46. Schuler G, Wirth C, Klisch K, Failing K, Hoffmann B, 2000 : Characterization of proliferative activity in bovine placentomes between day 150 and parturition by quantitative immunohistochemical detection of Ki67-antigen. Reprod Domest Anim 35, 157 162.
47. Schuler G, Wirth C, Teichmann U, Failing K, Leiser R, Thole H, Hoffmann B, 2002 : Occurrence of estrogen receptor alpha in bovine placentomes throughout mid and late gestation and at parturition. Biol Reprod 66, 976 982.
48. Schuler G, Teichmann U, Taubert A, Failing K, Hoffmann B, 2005 : Estrogen receptor beta (ERbeta) is expressed differently from ERalpha in bovine placentomes. Exp Clin Endocrinol Diabetes 113, 107 114.
49. Schutzer WE, Holtan DW, 1996 : Steroid transformations in pregnant mares: metabolism of exogenous progestins and unusual metabolic activity in vivo and in vitro. Steroids 61, 94 99.
50. Tait AD, Hodge LC, Allen WR, 1983 : Biosynthesis of 3 beta-hydroxy-5,7-pregnadien-20-one by the horse fetal gonad. FEBS Lett 153, 161 164.
51. Tseng L, Zhu HH, 1997 : Regulation of progesterone receptor messenger ribonucleic acid by progestin in human endometrial stromal cells. Biol Reprod 57, 1360 1366.
52. Turner KJ, Macpherson S, Millar MR, McNeilly AS, Williams K, Cranfield M, Groome NP, Sharpe RM, Fraser HM, Saunders PT, 2002 : Development and validation of a new monoclonal antibody to mammalian aromatase. J Endocrinol 172, 21 30.
53. Wehling M, Lösel R, 2006 : Non-genomic steroid hormone effects: membrane or intracellular receptors? J Steroid Biochem Mol Biol 102, 180 183.
54. Wooding FB, Wathes DC, 1980 : Binucleate cell migration in the bovine placentome. J Reprod Fertil 59, 425 430.