메뉴 건너뛰기




Volumn 62, Issue 5, 2004, Pages 714-718

Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; FLUPIRTINE MALEATE; PLACEBO; PRION PROTEIN;

EID: 10744219944     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000113764.35026.EF     Document Type: Article
Times cited : (171)

References (18)
  • 1
    • 0037154135 scopus 로고    scopus 로고
    • Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease
    • Otto M, Wiltfang J, Cepek L, et al. Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology 2002;58:192-197.
    • (2002) Neurology , vol.58 , pp. 192-197
    • Otto, M.1    Wiltfang, J.2    Cepek, L.3
  • 2
    • 0042845853 scopus 로고    scopus 로고
    • Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
    • Wiltfang J, Esselmann H, Smirnov A, et al. Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Ann Neurol 2003;54:263-267.
    • (2003) Ann Neurol , vol.54 , pp. 263-267
    • Wiltfang, J.1    Esselmann, H.2    Smirnov, A.3
  • 3
    • 0033573778 scopus 로고    scopus 로고
    • Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples
    • Hill AF, Butterworth RJ, Joiner S, et al. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 1999;353:183-189.
    • (1999) Lancet , vol.353 , pp. 183-189
    • Hill, A.F.1    Butterworth, R.J.2    Joiner, S.3
  • 4
    • 0037172849 scopus 로고    scopus 로고
    • Drug therapy in human and experimental transmissible spongiform encephalopathy
    • Brown P. Drug therapy in human and experimental transmissible spongiform encephalopathy. Neurology 2002;58:1720-1725.
    • (2002) Neurology , vol.58 , pp. 1720-1725
    • Brown, P.1
  • 6
    • 0035090680 scopus 로고    scopus 로고
    • Prions: Disease propagation and disease therapy by conformational transmission
    • Soto C, Saborio GP. Prions: disease propagation and disease therapy by conformational transmission. Trends Mol Med 2001;7:109-114.
    • (2001) Trends Mol Med , vol.7 , pp. 109-114
    • Soto, C.1    Saborio, G.P.2
  • 7
    • 0036194357 scopus 로고    scopus 로고
    • Flupirtine blocks apoptosis in Batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons
    • Dhar S, Bitting RL, Rylova SN, et al. Flupirtine blocks apoptosis in Batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons. Ann Neurol 2002;51:448-466.
    • (2002) Ann Neurol , vol.51 , pp. 448-466
    • Dhar, S.1    Bitting, R.L.2    Rylova, S.N.3
  • 8
    • 1842371505 scopus 로고    scopus 로고
    • Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro: Prevention of amyloid-induced glutathione depletion
    • Müller WE, Romero FJ, Perovic S, Pergande G, Pialoglou P. Protection of flupirtine on beta-amyloid-induced apoptosis in neuronal cells in vitro: prevention of amyloid-induced glutathione depletion. J Neurochem 1997;68:2371-2377.
    • (1997) J Neurochem , vol.68 , pp. 2371-2377
    • Müller, W.E.1    Romero, F.J.2    Perovic, S.3    Pergande, G.4    Pialoglou, P.5
  • 9
    • 0031257755 scopus 로고    scopus 로고
    • Effect of flupirtine on Bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP106-126)
    • Perovic S, Schröder HC, Pergande G, Ushijima H, Muller WE. Effect of flupirtine on Bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP106-126). Exp Neurol 1997;147:518-524.
    • (1997) Exp Neurol , vol.147 , pp. 518-524
    • Perovic, S.1    Schröder, H.C.2    Pergande, G.3    Ushijima, H.4    Muller, W.E.5
  • 10
    • 0032816292 scopus 로고    scopus 로고
    • Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects
    • Parchi P, Giese A, Capellari S, et al. Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Ann Neurol 1999;46:224-233.
    • (1999) Ann Neurol , vol.46 , pp. 224-233
    • Parchi, P.1    Giese, A.2    Capellari, S.3
  • 11
    • 0007951429 scopus 로고    scopus 로고
    • Geneva: World Health Organization
    • World Health Organization. Consensus on criteria for sporadic CJD, Geneva: World Health Organization, 1998.
    • (1998) Consensus on Criteria for Sporadic CJD
  • 12
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141:1356-1364.
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2    Davis, K.L.3
  • 13
    • 0016823810 scopus 로고
    • "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatrt Res 1975;12:189-198.
    • (1975) J Psychiatrt Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 16
    • 0028270519 scopus 로고
    • A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
    • The Tacrine Study Group
    • Knapp MJ, Knopman DS, Solomon PR, Pendlebury WW, Davis CS, Gracon SI. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. JAMA 1994;271:985-991.
    • (1994) JAMA , vol.271 , pp. 985-991
    • Knapp, M.J.1    Knopman, D.S.2    Solomon, P.R.3    Pendlebury, W.W.4    Davis, C.S.5    Gracon, S.I.6
  • 17
    • 0018687930 scopus 로고
    • A multiple testing procedure for clinical trials
    • O'Brien PC, Fleming TR. A multiple testing procedure for clinical trials. Biometrics 1979;35:549-556.
    • (1979) Biometrics , vol.35 , pp. 549-556
    • O'Brien, P.C.1    Fleming, T.R.2
  • 18
    • 0031792788 scopus 로고    scopus 로고
    • Antioxidant properties of the triaminopyridine, flupirtine
    • Gassen M, Pergande G, Youdim MB. Antioxidant properties of the triaminopyridine, flupirtine. Biochem Pharmacol 1998;56:1323-1329.
    • (1998) Biochem Pharmacol , vol.56 , pp. 1323-1329
    • Gassen, M.1    Pergande, G.2    Youdim, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.