Expression profiling of persistent polyclonal B-cell lymphocytosis suggests constitutive expression of the AP-1 transcription complex and downregulation of Fas-apoptotic and TGFβ signalling pathways

Leukemia

Volumn 23, Issue 3, 2009, Pages 581-583

  Lawrie, C H ^a   Shilling, R ^a   Troussard, X ^b   Cattan, H ^a   Mossafa, H ^c   Pezzella, F ^a   Boultwood, J ^a   Wainscoat, J S ^a   Hatton, C S R ^d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CAEN UNIVERSITY HOSPITAL   (France)

^c Laboratoire Pasteur   (France)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA;

ADULT; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL GROWTH; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GROWTH REGULATION; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; LYMPHOCYTOSIS; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

EID: 62549140192     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.223     Document Type: Article

References (8)

1. Mossafa H, Malaure H, Maynadie M, Valensi F, Schillinger F, Garand R et al. Persistent polyclonal B lymphocytosis with binucleated lymphocytes: A study of 25 cases. Groupe Francais d'Hematologie Cellulaire. Br J Haematol 1999; 104: 486-493.
2. Ozanne BW, Spence HJ, McGarry LC, Hennigan RF. Transcription factors control invasion: AP-1 the first among equals. Oncogene 2007; 26: 1-10.
3. Watanabe M, Sasaki M, Itoh K, Higashihara M, Umezawa K, Kadin ME et al. JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD30 promoter in anaplastic large cell lymphoma and reed-sternberg cells of Hodgkin lymphoma. Cancer Res 2005; 65: 7628-7634.
4. Willenbrock K, Kuppers R, Renne C, Brune V, Eckerle S, Weidmann E et al. Common features and differences in the transcriptome of large cell anaplastic lymphoma and classical Hodgkin's lymphoma. Haematologica 2006; 91: 596-604.
5. Roussel M, Roue G, Sola B, Mossafa H, Troussard X. Dysfunction of the Fas apoptotic signaling pathway in persistent polyclonal B-cell lymphocytosis. Haematologica 2003; 88: 239-240.
6. Capra M, Nuciforo PG, Confalonieri S, Quarto M, Bianchi M, Nebuloni M et al. Frequent alterations in the expression of serine/threonine kinases in human cancers. Cancer Res 2006; 66: 8147-8154.
7. Sakane-Ishikawa E, Nakatsuka S, Tomita Y, Fujita S, Nakamichi I, Takakuwa T et al. Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: A study of the Osaka Lymphoma Study Group. J Clin Oncol 2005; 23: 8012-8017.
8. Miyaki M, Kuroki T. Role of Smad4 (DPC4) inactivation in human cancer. Biochem Biophys Res Commun 2003; 306: 799-804.