Sequencing the full-length of the phosphatase and tensin homolog (PTEN) gene in hepatocellular carcinoma (HCC) using the 454 GS20 and illumina GA DNA sequencing platforms

World Journal of Surgery

Volumn 33, Issue 4, 2009, Pages 647-652

  Rodriguez, Joel A ^a   Guiteau, Jacfranz J ^a   Nazareth, Lynne ^a   Reid, Jeff G ^a   Goss, John A ^a   Gibbs, Richard A ^a   Gingras, Marie Claude ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE FREQUENCY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

CARCINOMA, HEPATOCELLULAR; EXONS; GENE LIBRARY; GENES, TUMOR SUPPRESSOR; HUMANS; INTEINS; LIVER NEOPLASMS; POLYMERASE CHAIN REACTION; PTEN PHOSPHOHYDROLASE; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN;

EID: 62549103785     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-008-9852-x     Document Type: Article

References (9)

1. C Greenman P Stephens R Smith 2007 Patterns of somatic mutation in human cancer genomes Nature 446 153 158
2. T Sjoblom S Jones L Wood 2006 The consensus coding sequences of human breast and colorectal cancers Science 314 268 274
3. M Margulies M Egholm WE Altman 2005 Genome sequencing in microfabricated high-density picolitre reactors Nature 437 376 380
4. T Maehama JE Dixon 1999 PTEN: a tumour suppressor that functions as a phospholipid phosphatase Trends Cell Biol 9 125 128
5. JJ Bae JW Rho TJ Lee 2007 Loss of heterozygosity on chromosome 10q23 and mutation of the phosphatase and tensin homolog deleted from chromosome 10 tumor suppressor gene in Korean hepatocellular carcinoma patients Oncol Rep 18 1007 1013
6. N Kawamura H Nagai K Bando 1999 PTEN/MMAC1 mutations in hepatocellular carcinomas: somatic inactivation of both alleles in tumors Jpn J Cancer Res 90 413 418
7. A Carnero C Blanco-Aparicio O Renner 2008 The PTEN/PI3 K/AKT signaling pathway in cancer, therapeutic implications Curr Cancer Drug Targets 8 187 198
8. L Wang WL Wang Y Zhang 2007 Epigenetic and genetic alterations of PTEN in hepatocellular carcinoma Hepatol Res 37 389 396
9. TH Hu CC Huang PR Lin 2003 Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma Cancer 97 1929 1940