Reply to Bayry et al.: The anti-inflammatory activity of sialylated IgG Fcs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 9, 2009, Pages

  Ravetch, Jeffrey ^a   Anthony, Robert ^a   Wermeling, Fredrik ^b   Karlsson, Mikael ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2,6 SIALIC ACID; FC RECEPTOR IIA; IMMUNOGLOBULIN; IMMUNOGLOBULIN FC FRAGMENT; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SIALIC ACID; SIALOPROTEIN; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; DENDRITIC CELL; GLOMERULONEPHRITIS; HUMAN; LETTER; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SIALYLATION; THROMBOCYTOPENIA; WESTERN BLOTTING;

EID: 62549095427     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0900445106     Document Type: Letter

References (10)

1. Bayry J, Bansal K, Kazatchkine MD, Kaveri SV (2009) DC-SIGN and 2,6-sialylated IgG Fc interaction is dispensable for the anti-inflammatory activity of IVIg on human dendritic cells. Proc Natl Acad Sci USA 106:E24.
2. Anthony RM, Wermeling F, Karlsson MC, Ravetch JV (2008) Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc Natl Acad Sci USA 105:19571-19578.
3. Samuelsson A, Towers TL, Ravetch JV (2001) Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. Science 291:484-486.
4. Bruhns P, Samuelsson A, Pollard JW, Ravetch JV (2003) Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity 18:573-581.
5. Kaneko Y, Nimmerjahn F, Madaio MP, Ravetch JV (2006) Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors. J Exp Med 203:789-797.
6. Kaneko Y, Nimmerjahn F, Ravetch JV (2006) Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science 313:670-673.
7. Nimmerjahn F, Ravetch JV (2007) The antiinflammatory activity of IgG: The intravenous IgG paradox. J Exp Med 204:11-15.
8. Nimmerjahn F, Ravetch JV (2008) Anti-inflammatory actions of intravenous immunoglobulin. Annu Rev Immunol 26:513-533.
9. Anthony RM, et al. (2008) Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. Science 320:373-376.
10. Debre M, et al. (1993) Infusion of Fc gamma fragments for treatment of children with acute immune thrombocytopenic purpura. Lancet 342:945-949.