The discriminative stimulus effects of dopamine D2- and D3-preferring agonists in rats

Psychopharmacology

Volumn 203, Issue 2, 2009, Pages 317-327

  Koffarnus, Mikhail N ^a   Greedy, Benjamin ^c   Husbands, Stephen M ^c   Grundt, Peter ^d   Newman, Amy Hauck ^e   Woods, James H ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c University of Bath   (United Kingdom)

^d UNIVERSITY OF MINNESOTA DULUTH   (United States)

^e NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

D2; D3; Dopamine; Drug discrimination; Either or discrimination; Pramipexole; Rat; Sumanirole

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; COCAINE; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR STIMULATING AGENT; L 741626; PG 01037; PRAMIPEXOLE; QUINPIROLE; SUMANIROLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION;

ANIMALS; BENZIMIDAZOLES; BENZOTHIAZOLES; COCAINE; CONDITIONING, OPERANT; DISCRIMINATION (PSYCHOLOGY); DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; TETRAHYDRONAPHTHALENES;

EID: 62449312235     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-008-1323-4     Document Type: Article

References (26)

1. A Argiolas MR Melis 1998 The neuropharmacology of yawning Eur J Pharmacol 343 1 16
2. 1 activation Pharmacol Biochem Behav 60 313 319
3. 2 receptor mRNA Brain Res 564 203 219
4. 2 autoreceptors Neuropharmacology 37 793 802
5. PM Callahan DLG Garza II KA Cunningham 1997 Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems Pharmacol Biochem Behav 57 601 607
6. WF Caul RJ Barrett EM Huffman JR Stadler 1996 Rebound responding following a single dose of drug using an amphetamine-vehicle-haloperidol drug discrimination Psychopharmacology (Berl) 128 274 279
7. AJ Christian AK Goodwin LE Baker 2001 Antagonism of the discriminative stimulus effects of (+)-7-OH-DPAT by remoxipride but not PNU-99194A Pharmacol Biochem Behav 68 371 377
8. GT Collins AH Newman P Grundt KC Rice SM Husbands C Chauvignac J Chen S Wang JH Woods 2007 Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists Psychopharmacology (Berl) 193 159 170
9. P Grundt SLJ Husbands RR Luedtke M Taylor AH Newman 2007 Analogues of the dopamine D2 receptor antagonist L741,626: binding, function, and SAR Bioorg Med Chem Lett 17 745 749
10. P Grundt KM Prevatt J Cao M Taylor CZ Foresca J Choi BG Jenkins RR Luedke AH Newman 2007 Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin- 1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents J Med Chem 50 4135 4146
11. JL Katz KL Alling 2000 Discriminative stimulus effects of putative D3 dopamine receptor agonists in rats Psychopharmacology (Berl) 11 483 493
12. MS Kleven W Koek 1997 Discriminative stimulus properties of cocaine: enhancement by β-adrenergic receptor antagonists Psychopharmacology (Berl) 131 307 312
13. MS Kleven W Koek 1998 Discriminative stimulus properties of cocaine: enhancement by monoamine reuptake blockers J Pharmacol Exp Ther 284 1015 1025
14. W Koek LP Carter RJ Lamb W Chen H Wu A Coop CP France 2005 Discriminative stimulus effects of γ-hydroxybutyrate (GHB) in rats discriminating GHB from baclofen and diazepam J Pharmacol Exp Ther 314 170 179
15. 2-selective receptor agonist: in vitro and in vivo pharmacological characterization and efficacy in animal models of Parkinson's disease J Pharmacol Exp Ther 314 1248 1256
16. 2 receptors Neuropharmacology 39 586 598
17. 3 receptors Psychopharmacology (Berl) 191 767 782
18. Motulsky HJ, Christopoulos A (2003) Fitting models to biological data using linear and nonlinear regression: a practical guide to curve fitting. GraphPad Software, San Diego
19. 2-adrenoceptor J Pharmacol Exp Ther 303 805 814
20. DA Overton 1982 Multiple drug training as a method for increasing the specificity of the drug discrimination procedure J Pharmacol Exp Ther 221 166 172
21. MA Parada M Puig de Parada P Rada L Hernandez 1995 Sulpiride increases and dopamine decreases intracranial temperature in rats when injected in the lateral hypothalamus: an animal model for the neuroleptic malignant syndrome? Brain Res 674 117 121
22. AJ Prus SD Philibin AL Pehrson JH Porter 2006 Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle Behav Pharmacol 17 185 194
23. AH Tang SR Franklin 1987 Discriminative stimulus effects of a low dose of apomorphine in the rat Psychopharmacology (Berl) 91 61 66
24. GB Varty GA Higgins 1997 Investigations into the nature of a 7-OH-DPAT discriminative cue: comparisons with d-amphetamine Eur J Pharmacol 339 101 107
25. Wang S, Chen J, Gollins GT, Zhang J, Yang C, Levant B, Woods JH (2008) Design, synthesis, and evaluation of highly selective dopamine D3 ligands with a novel profile of pharmacological and behavioral selectivity. J Med Chem (in press)
26. Zar JH (1999) Biostatistical analysis, 4th edn. Prentice Hall, Upper Saddle River