Frontolimbic function and cortisol reactivity in response to emotional stimuli

NeuroReport

Volumn 20, Issue 4, 2009, Pages 429-434

  Root, James C ^a,b   Tuescher, Oliver ^a,g   Cunningham Bussel, Amy ^a   Pan, Hong ^a   Epstein, Jane ^a   Altemus, Margaret ^b   Cloitre, Marylene ^d   Goldstein, Martin ^f   Silverman, Michael ^f   Furman, Daniella ^a   Ledoux, Joseph ^e   McEwen, Bruce ^c   Stern, Emily ^a   Silbersweig, David ^a  

^a Functional Neuro Imaging Laboratory   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Amygdala; Cortisol; Hippocampus; Medial prefrontal cortex; Neuroimaging

Indexed keywords

HYDROCORTISONE;

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; EMOTION; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HORMONE RESPONSE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIMBIC SYSTEM; MALE; NORMAL HUMAN; OXYGEN BLOOD LEVEL; PREFRONTAL CORTEX; PRIORITY JOURNAL; SALIVA ANALYSIS; SALIVA LEVEL; STRESS; VISUAL STIMULATION; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FRONTAL LOBE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; SALIVA; VISION;

ADULT; EMOTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FRONTAL LOBE; HUMANS; HYDROCORTISONE; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; SALIVA; VISUAL PERCEPTION; YOUNG ADULT;

EID: 62449133916     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e328326a031     Document Type: Article

References (24)

1. Morgane PJ, Galler JR, Mokier DJ. A review of systems and networks of the limbic forebrain/limbic midbrain. Prog Neurobiol 2005; 75:143-160.
2. LeDoux J. The emotional brain, fear, and the amygdala. Cell Mol Neurobiol 2003; 23:727-738.
3. Urry HL, van Reekum CM, Johnstone T, Kalin NH, Thurow ME, Schaefer HS, et al. Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of Cortisol secretion among older adults. J Neurosci 2006; 26:4415-4425.
4. O'Mara S. Controlling hippocampal output: the central role of subiculum in hippocampal information processing. Behav Brain Res 2006; 174:304-312.
5. McEwen BS, Magarinos AM. Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders. Hum Psychopharmacol 2001; 16:S7-S19.
6. Sullivan RM, Gratton A. Lateralized effects of medial prefrontal cortex lesions on neuroendocrine and autonomie stress responses in rats. J Neurosci 1999; 19:2834-2840.
7. Vermetten E, Bremner JD. Circuits and systems in stress. I. Preclinical studies. Depress Anxiety 2002; 15:126-147.
8. Xu Y, Day TA, Buller KM. The central amygdala modulates hypothalamic-pituitary-adrenal axis responses to systemic interleukin-1 beta administration. Neuroscience 1999; 94:175-183.
9. Ma S, Morilak DA. Norepinephrine release in medial amygdala facilitates activation of the hypothalamic-pituitary-adrenal axis in response to acute immobilisation stress. J Neuroendocrinol 2005; 17:22-28.
10. De Leon MJ, McRae T, Rusinek H, Convit A, De Santi S, Tarshish C, et al. Cortisol reduces hippocampal glucose metabolism in normal elderly, but not in Alzheimer's disease. J Clin Endocrinol Metab 1997; 82:3251-3259.
11. Phelps EA, LeDoux JE. Contributions of the amygdala to emotion processing: from animal models to human behavior. Neuron 2005; 48:175-187.
12. LeDoux JE. Emotion circuits in the brain. Annu Rev Neurosci 2000; 23:155-184.
13. Quirk GJ, Likhtik E, Pelletier JG, Pare D. Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons. J Neurosci 2003; 23:8800-8807.
14. Rosenkranz JA, Moore H, Grace AA. The prefrontal cortex regulates lateral amygdala neuronal plasticity and responses to previously conditioned stimuli. J Neurosci 2003; 23:11054-11064.
15. Herman JP, Ostrander MM, Mueller NK, Rgueiredo H. Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29:1201-1213.
16. Feldman S, Conforti N, Weidenfeld J. Limbic pathways and hypothalamic neurotransmitters mediating adrenocortical responses to neural stimuli. Neurosci Biobehav Rev 1995; 19:235-240.
17. Van de Kar LD, Blair ML Forebrain pathways mediating stress-induced hormone secretion. Front Neuroendocrinol 1999; 20:1-48.
18. Anagnostaras SG, Gale GD, Fanselow MS. Hippocampus and contextual fear conditioning: recent controversies and advances. Hippocampus 2001; 11:8-17.
19. Phillips RG, LeDoux JE. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 1992; 106:274-285.
20. Kalisch R, Korenfeld E, Stephan KE, Weiskopf N, Seymour B, Dolan RJ. Context-dependent human extinction memory is mediated by a ventromedial prefrontal and hippocampal network. J Neurosci 2006; 26:9503-9511.
21. Stark R, Wolf OT, Tabbert K, Kagerer S, Zimmermann M, Kirsch P, et al. Influence of the stress hormone cortisol on fear conditioning in humans: evidence for sex differences in the response of the prefrontal cortex. Neuroimage 2006; 32:1290-1298.
22. Ochsner KN, Ray RD, Cooper JC, Robertson ER, Chopra S, Gabrieli JD, Gross JJ. For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion. Neuroimage 2004; 23:483-499.
23. Butler T, Pan H, Epstein J, Protopopescu X, Tuescher O, Goldstein M, et al. Fear-related activity in subgenual anterior cingulate differs between men and women. Neuroreport 2005; 16:1233-1236.
24. Liberzon I, King AP, Britton JC, Phan KL, Abelson JL, Taylor SF. Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuli. Am J Psychiatry 2007; 164:1250-1258.