Omeprazole significantly reduces posaconazole serum trough level

Clinical Infectious Diseases

Volumn 48, Issue 6, 2009, Pages 839-

  Alffenaar, Jan Willem C ^a   Van Assen, Sander ^a   Van Der Werf, Tjip S ^a   Kosterink, Jos G W ^a   Uges, Donald R A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; OMEPRAZOLE; POSACONAZOLE; PROTON PUMP INHIBITOR; TRIAZOLE DERIVATIVE;

ADULT; ASPERGILLOSIS; CASE REPORT; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; DRUG WITHDRAWAL; GASTROINTESTINAL HEMORRHAGE; HUMAN; LETTER; LIQUID CHROMATOGRAPHY; MALE; PRIORITY JOURNAL; SALVAGE THERAPY; TANDEM MASS SPECTROMETRY; CHEMISTRY; DRUG INTERACTION; NOTE; SERUM;

DRUG INTERACTIONS; HUMANS; OMEPRAZOLE; SERUM; TRIAZOLES;

EID: 62449091140     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/597110     Document Type: Letter

References (2)

1. Kosoglou T, Perentesis GP, Af'fiime MB, et al. The effect of antacid and cimetidine on the oral absorption of the antifungal agent SCH 39304, J Clin Pharmacol 1990; 30:638-42.
2. Jain R, Pottinger P. The effect of gastric acid on the absorption of posaconazole. Clin Infect Dis 2008;46:1627-8.