Severe Hemolytic Anemia Post-Renal Transplantation Produced by Donor Anti-D Passenger Lymphocytes: Case Report and Literature Review

Transfusion Medicine Reviews

Volumn 23, Issue 2, 2009, Pages 155-159

  Ainsworth, Craig D ^a,b   Crowther, Mark A ^a,b   Treleaven, Darin ^a,b   Evanovitch, Denise ^a,b   Webert, Kathryn E ^a,b   Blajchman, Morris A ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b HAMILTON REGIONAL LABORATORY MEDICINE PROGRAM   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RHESUS D ANTIBODY; RHESUS D ANTIGEN; TACROLIMUS; THYMOCYTE ANTIBODY;

ADULT; ANTIBODY TITER; ARTICLE; BLOOD GROUP ABO SYSTEM; BLOOD GROUP RHESUS SYSTEM; CASE REPORT; DISEASE SEVERITY; ERYTHROCYTE TRANSFUSION; FEMALE; GRAFT DYSFUNCTION; GRAFT FAILURE; HEMOLYSIS; HEMOLYTIC ANEMIA; HISTOCOMPATIBILITY; HUMAN; HYPERBILIRUBINEMIA; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; PASSENGER LYMPHOCYTE SYNDROME; POSTOPERATIVE COMPLICATION; STEM CELL TRANSPLANTATION;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ERYTHROCYTES; FEMALE; HEMOLYSIS; HUMANS; ISOANTIBODIES; KIDNEY TRANSPLANTATION; LYMPHOCYTES; MIDDLE AGED; TISSUE DONORS;

EID: 62349095239     PISSN: 08877963     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tmrv.2008.12.005     Document Type: Article

References (22)

1. Pomper G.J., Joseph R.A., Hartmann E.L., et al. Massive immune hemolysis caused by anti-D after dual kidney transplantation. Am J Transplant 5 (2005) 2586-2589
2. Ramsey G. Red cell antibodies arising from solid organ transplants. Transfusion 31 (1991) 76-86
3. Petz L.D. Immune hemolysis associated with transplantation. Semin Hematol 42 (2005) 145-155
4. Ramsey G., Israel L., Lindsay G.D., et al. Anti-Rho(D) in two Rh-positive patients receiving kidney grafts from an Rh-immunized donor. Transplantation 41 (1986) 67-69
5. Solheim B.G., Albrechtsen D., Egeland T., et al. Auto-antibodies against erythrocytes in transplant patients produced by donor lymphocytes. Transplant Proc 19 (1987) 4520-4521
6. Solheim B.G., Albrechtsen D., Berg K.J., et al. Hemolytic anemia in cyclosporine-treated recipients of kidney or heart grafts from donors with minor incompatibility for ABO antigens. Transplant Proc 19 (1987) 4236-4238
7. Albrechtsen D., Solheim B.G., Flatmark A., et al. Autoimmune hemolytic anemia in cyclosporine-treated organ allograft recipients. Transplant Proc 20 Suppl 3 (1988) 959-962
8. Swanson J., Sebring E., Sastamoinen R., et al. Gm allotyping to determine the origin of the anti-D causing hemolytic anemia in a kidney transplant recipient. Vox Sang 52 (1987) 228-230
9. Frohn C., Jabs W.J., Fricke L., et al. Hemolytic anemia after kidney transplantation: Case report and differential diagnosis. Ann Hematol 81 (2002) 158-160
10. Saba N.F., Sweeney J.D., Penn L.C., et al. Anti-D in a D-positive renal transplant patient. Transfusion 37 (1997) 321-324
11. Schwartz D., and Gotzinger P. Immune haemolytic anaemia (IHA) after solid organ transplantation due to Rhesus antibodies of donor origin: Report of 5 cases. Beitr Infusionther 30 (1992) 367-369
12. Knoop C., Andrien M., Antoine M., et al. Severe hemolysis due to a donor anti-D antibody after heart-lung transplantation. Association with lung and blood chimerism. Am Rev Respir Dis 148 (1993) 504-506
13. Sindhi R., Landmark J., Stratta R.J., et al. Humoral graft-versus-host disease after pancreas transplantation with an ABO-compatible and Rh-nonidentical donor. Case report and a rationale for preoperative screening. Transplantation 61 (1996) 1414-1416
14. Ramsey G., Kiss J.E., Sacher R.A., et al. Rh antibodies in two patients receiving liver and kidney-pancreas grafts from the same Rh-sensitized donor. Paper presented at the Joint Congress of the American Association of Blood Banks and the International Society of Blood Transfusion. Los Angeles, CA November 10-15, 1990. Book of Abstracts (1990), American Association of Blood Banks, Arlington, VA 198
15. Fung M.K., Sheikh H., Eghtesad B., et al. Severe hemolysis resulting from D incompatibility in a case of ABO-identical liver transplant. Transfusion 44 (2004) 1635-1639
16. Lee J.H., and Mintz P.D. Graft versus host anti-Rho(D) following minor Rh-incompatible orthotopic liver transplantation. Am J Hematol 44 (1993) 168-171
17. Flesland O., Solheim B.G., and Bergan A. Red cell antibody production due to primary immune response by lymphoid tissue in a grafted liver. Transpl Immunol 1 (1993) 86-87
18. Calhoun B., Pothiawala M., Musa G., et al. Indicators of clinically significant red cell antibodies produced by sensitized lymphocytes in liver transplant patients. Immunohematol 7 (1991) 37-39
19. Shortt J., Westall G.P., Roxby D., et al. A 'dangerous' group O donor: Severe hemolysis in all recipients of organs from a donor with multiple red cell alloantibodies. Am J Transplant 8 (2008) 711-714
20. Bernasconi N.L., Traggiai E., and Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298 (2002) 2199-2202
21. Manz R.A., Thiel A., and Radbruch A. Lifetime of plasma cells in the bone marrow. Nature 388 (1997) 133-134
22. Cassese G., Lindenau S., de Boer B., et al. Inflamed kidneys of NZB/W mice are a major site for the homeostasis of plasma cells. Eur J Immunol 31 (2001) 2726-2732