Impact of aciclovir on genital and plasma HIV-1 RNA in HSV-2/HIV-1 co-infected women: A randomized placebo-controlled trial in South Africa

AIDS

Volumn 23, Issue 4, 2009, Pages 461-469

  Delany, Sinéad ^a,b   Mlaba, Nonkululeko ^a   Clayton, Tim ^b   Akpomiemie, Godspower ^a   Capovilla, Alexio ^a   Legoff, Jerome ^c   Belec, Laurent ^d   Stevens, Wendy ^a   Rees, Helen ^a   Mayaud, Philippe ^b  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c SAINT LOUIS HOSPITAL   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Aciclovir; Herpes simplex virus type 2 (HSV 2); HIV 1; Randomized controlled trial; South Africa; Suppressive therapy

Indexed keywords

ACICLOVIR; PLACEBO; VIRUS DNA; VIRUS RNA;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL TRIAL; CONCURRENT INFECTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GENITAL HERPES; GENITAL ULCER; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; VIRUS TRANSMISSION;

ACYCLOVIR; ADULT; ANTIVIRAL AGENTS; CD4 LYMPHOCYTE COUNT; CERVIX UTERI; DNA, VIRAL; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HIV INFECTIONS; HIV-1; HUMANS; MIDDLE AGED; RNA, VIRAL; SEXUAL BEHAVIOR; SPECIMEN HANDLING; TREATMENT OUTCOME; VAGINA; VIRUS SHEDDING; YOUNG ADULT;

EID: 62349083377     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32831db217     Document Type: Article

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