Evaluating the similarity of complex drinking-water disinfection by-product mixtures: Overview of the issues

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 72, Issue 7, 2009, Pages 429-436

  Rice, Glenn E ^a   Teuschler, Linda K ^a   Bull, Richard J ^b   Simmons, Jane E ^c   Feder, Paul I ^d  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b MoBull Consulting   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; CHLORINE; DISINFECTION BY PRODUCT; DRINKING WATER; MUTAGENIC AGENT; ORGANOHALOGEN DERIVATIVE; TRIHALOMETHANE; UNCLASSIFIED DRUG;

BIOASSAY; BOOTSTRAPPING; CARCINOGENICITY; CHEMICAL COMPOSITION; CHLORINATION; CHLOROAMINATION; DOSE RESPONSE; MUTAGENICITY; OZONATION; POLLUTION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; REVIEW; RISK ASSESSMENT; SPONTANEOUS ABORTION; TOTAL ORGANIC CARBON; WATER QUALITY; WATER SUPPLY; WATER TREATMENT;

ANIMALS; COMPLEX MIXTURES; DISINFECTANTS; DISINFECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; RISK ASSESSMENT; WATER POLLUTANTS; WATER SUPPLY;

EID: 62249196886     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390802608890     Document Type: Review

References (25)

1. Bull, R. J., Teuschler, L., and Rice, G. 2009a. Determinants of whether or not mixtures of disinfection by-products are similar. J. Toxicol. Environ. Health A. 72:437-460.
2. Bull, R. J., Rice, G., Teuschler, L., and Feder, P. I. 2009b. Chemical measures of similarity among disinfection by-product mixtures. J. Toxicol. Environ. Health A. 72:429-436.
3. Chen, J. J., Chen, Y. J., Teuschler, L. K., Rice, G., Hamernik, K., Protzel, A., and Kodell, R. L. 2003. Cumulative risk assessment for quantitative response data. Environmetrics 14:339-353.
4. Cizmas, L., McDonald, T. J., Phillips, Traci, D., Gillespie, A. M., Lingenfelter, R. A., Kubena, L. F., Phillips, Timothy D., and Donnelly, K. C. 2004. Toxicity characterization of complex mixtures using biological and chemical analysis in preparation for assessment of mixture similarity. Environ. Sci. Technol. 38:5127-5133.
5. Cogliano, V. 1998. Assessing the cancer risk from environmental PCBs. Environ. Health Perspect. 106:317-323.
6. DeRosa, C. El-Masri, H.A., Pohl, H., Cibulas, W. and Mumtaz, M.M. 2004. Implications of chemical mixtures in public health practice. J. Toxicol. Environ. Health B 7:339-350.
7. Eide, I., Neverdal, G., Thorvaldsen, B., Grung, B., and Kvalheim, O. M. 2002. Toxicological evaluation of complex mixtures by pattern recognition: Correlating chemical fingerprints to mutagenicity. Environ. Health Perspect. 110:985-988.
8. Feder, P. I., Ma, Z., Bull, R. J., Teuschler, L. K., Schenck, K. M., Simmons, J. E., and Rice, G. E. 2009a. Evaluating sufficient similarity for disinfection by-product (DBP) similar mixtures via multivariate statistical procedures. J. Toxicol. Environ. Health A. 72:468-481.
9. Feder, P. I., Ma, Z., Bull, R. J., Teuschler, L. K., and Rice, G. E. 2009b. Evaluating sufficient similarity for drinking water disinfection by-product (DBP) mixtures with bootstrap hypothesis test procedures. J. Toxicol. Environ. Health A. 72:494-504.
10. Lewtas, J. 1985. Development of a comparative potency method for cancer risk assessment of complex mixtures using short-term in vivo and in vitro bioassays. Toxicol. Ind. Health 1:193-203.
11. Lewtas, J. 1988. Genotoxicity of complex mixtures: Strategies for the identification and comparative assessment of airborne mutagens and carcinogens from combustion sources. Fundam. Appl. Toxicol. 10:571-589.
12. Nesnow, S. 1990. Mouse skin tumours and human lung cancer: Relationships with complex environmental emissions. In Complex mixtures and cancer risk, IARC Scientific Publ. 104, pp. 44-54. Lyon, France: IARC.
13. Rice, G., Teuschler, L E., Speth, T. F., Richardson, S. D., Miltner, R. J., Schenck, K., Gennings, C., Hunter, E. S. III, Narotsky, M. G., and Simmons, J E. 2008. Assessing reproductive and developmental risks posed by complex disinfection by-product mixtures. J. Toxicol. Environ. Health. A 71:1222-1234.
14. Schenck, K. M., Sivaganesan, M., and Rice, G. 2009. Correlations of water quality parameters with mutagenicity of chlorinated drinking water samples J. Toxicol. Environ. Health A. 72:461-467.
15. Schenck, K. M., Wymer, L. J., Lykins, B. W., Clark, R. M. 1998. Application of a Finnish mutagenicity model to drinking waters in the US. Chemosphere 37:451-464.
16. Simmons, J. E., Richardson, S. D., Teuschler, L. K, Miltner, R. J., Speth, T. F., Schenck, K. M., Hunter, E. S. III, and Rice, G. 2008. Research issues underlying the four-lab study: Integrated disinfection byproducts mixtures research. J. Toxicol. Environ. Health. A 71:1125-1132.
17. Simmons, J. E., Richardson, S. D., Speth, T. F., Miltner, R. J., Rice, G., Schenck, K. M., Hunter, E. S. III, and Teuschler, L. K. 2002. Development of a research strategy for integrated technology-based toxicological and chemical evaluation of complex mixtures of drinking water disinfection byproducts. Environ. Health Perspect. 110(suppl. 6):1013-1024.
18. Simmons, J. E., and Teuschler, L. K. In Press. Chemistry, toxicity and health risk assessment of drinking water disinfection byproducts. In. The Principles and practice of mixtures toxicology. M. Mumtaz. In press.
19. Stork, L. G., Gennings, C., Carter, W. H., Jr., Teuschler, L. K., and Carney, E. W. 2008. Empirical evaluation of sufficient similarity in dose-responsiveness for environmental risk assessment of chemical mixtures. J. Agric. Biol. Environ. S. 13:313-333.
20. Teuschler, L. K., and Simmons, J. E. 2003. Approaching the toxicity of disinfection by-products in drinking water as a mixtures problem. J. Am. Water Works Assoc. 95:131-138.
21. U.S. Environmental Protection Agency. 1986. Guidelines for the health risk assessment of chemical mixtures. Fed. Reg. 51(185):34014-34025.
22. U.S. Environmental Protection Agency. 1996. PCBs: Cancer dose-response assessment and application to environmental mixtures. Washington, DC: National Center for Environmental Assessment. EPA/600/P-96/001F.
23. U.S. Environmental Protection Agency. 2000. Supplementary guidance for conducting health risk assessment of chemical mixtures. External scientific peer review draft. Washington, DC: U.S. Environmental Protection Agency. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=29260.
24. U.S. Environmental Protection Agency/AMWA. (1989). Disinfection b y-products in United States drinking waters. Final report. James M. Montgomery Consulting Engineers and the Metropolitan Water District of Southern California. Los Angeles, CA.
25. Waller, K., Swan, S. H., DeLorenze. G., and Hopkins, B. 1998. Trihalomethanes in drinking water and spontaneous abortion. Epidemiology 9:134-140.