Assessment of levels of organochlorine pesticides and their metabolites in the hair of a Greek rural human population

Human and Experimental Toxicology

Volumn 27, Issue 12, 2008, Pages 933-940

  Tsatsakis, A M ^a   Tzatzarakis, M N ^a   Tutudaki, M ^a   Babatsikou, F ^b   Alegakis, A K ^a   Koutis, C ^b  

^a UNIVERSITY OF CRETE   (Greece)

^b UNIVERSITY OF WEST ATTICA   (Greece)

Author keywords

DDTs; Exposure; GC MS; Hair; Hexachlorocyclohexanes; Organochlorines

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHANE; 1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; ALPHA HEXACHLOROCYCLOHEXANE; CHLORPHENOTANE; HEXACHLOROBENZENE; HEXACHLOROCYCLOHEXANE; LINDANE; MITOTANE; ORGANOCHLORINE PESTICIDE; ORTHO PARA 1,1 DICHLORO 2,2 BIS (4 CHLOROPHENYL)ETHYLENE; ORTHO PARA 1,1,1 TRICHLORO 2,2 BIS(4 CHLOROPHENYL) ETHANE; PARA PARA 1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; PARA PARA 1,1,1 TRICHLORO 2,2 BIS(4 CHLOROPHENYL) ETHANE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; EXPOSURE VARIABLE; FEMALE; GAS CHROMATOGRAPHY; HAIR ANALYSIS; HUMAN; HUMAN TISSUE; MALE; MASS SPECTROMETRY; PREVALENCE; PRIORITY JOURNAL;

ADULT; AGE DISTRIBUTION; AGED; BIOTRANSFORMATION; DDT; ENVIRONMENTAL MONITORING; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GREECE; HAIR; HUMANS; LINDANE; MALE; MIDDLE AGED; PESTICIDES; RURAL HEALTH;

EID: 62249180010     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/0960327108102047     Document Type: Article

References (22)

1. 1 World Health Organization. Environmental Health Criteria 83, DDT and its derivatives, environmental effects. Geneva: World Health Organization ; 1989.
2. 2 Augustijn-Beckers PWM;.Hornsby AG;.Wauchope RD;.. SCS/ARS/CES pesticide properties database for environmental decision-making II. Additional compounds. Rev Environ Contam Toxicol 1994; 137: 1-82, 5-21.
3. McIntyre JK. Beauchamp DA.. Age and trophic position dominate bioaccumulation of mercury and organochlorines in the food web of Lake Washington. Sci Total Environ 2007 ; 372: 571-584.
4. Hansi RK. Farooq M. Babu GS. Srivastava SP. Joshi PC. Viswanathan PN.. Agricultural produce in the dry bed of the River Ganga in Kanpur, India-a new source of pesticide contamination in human diets. Food Chem Toxicol 1999 ; 37: 847-852.
5. Saradha B. Vaithinathan S. Mathur PP.. Lindane alters the levels of HSP70 and clusterin in adult rat testis. Toxicology 2008 ; 243: 116-123.
6. Johri A. Dhawan A. Singh RL. Parmar D.. Persistence in alterations in the ontogeny of cerebral and hepatic cytochrome P450s following prenatal exposure to low doses of lindane. Toxicol Sci 2008 ; 101: 331-340.
7. Betoulle S. Duchiron C. Deschaux P.. Lindane increases in vitro respiratory burst activity and intracellular calcium levels in rainbow trout (Oncorhynchus mykiss) head kidney phagocytes. Aquat Toxicol 2000 ; 48: 211-221.
8. Covaci A. Tutudaki M. Tsatsakis AM. Schepens P.. Hair analysis: another approach for the assessment of human exposure to selected persistent organochlorine pollutants. Chemosphere 2002 ; 46: 413-418.
9. Schramm KW.. Hair: a matrix for non-invasive biomonitoring of organic chemicals in mammals. Bull Environ Contam Toxicol 1997 ; 59: 396-402.
10. Covaci A. Schepens P.. Chromatographic aspects for the determination of selected persistent organochlorine pollutants in human hair. Chromatographia 2001 ; 53: 366-371.
11. Altshul L. Covaci A. Hauser R.. The relationship between levels of PCBs and pesticides in human hair and blood. Preliminary results. Environ Health Perspect 2004 ; 112: 1193-1199.
12. D'Havé H. Scheirs J. Covaci A. Schepens P. Verhagen R. De Coen W.. Nondestructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus). III. Hair as an indicator of endogeneous organochlorine compound concentrations. Environ Toxicol Chem 2006 ; 25: 158-167.
13. Tsatsakis A. Tutudaki M.. Progress in pesticide and POPs hair analysis for the assessment of exposure. Forensic Sci Int 2004 ; 145: 195-199.
14. Tsatsakis AM. Tzatzarakis MN. Tutudaki M.. Pesticide levels in head hair samples of Cretan population as an indicator of present and past exposure. Forensic Sci Int 2008 ; 176: 67-71.
15. Tutudaki M. Tsakalof AK. Tsatsakis AM.. Hair analysis used to assess chronic exposure to the organophosphate diazinon: a model study with rabbits. Hum Exp Toxicol 2003 ; 22: 159-164.
16. Neuber K. Merkel G. Randow FFE.. Indoor air pollution by lindane and DDT indicated by head hair samples of children. Toxicol Lett 1999 ; 107: 189-192.
17. Posecion N. Ostrea E. Bielawski D. Corrion M. Seagraves J. Jin Y.. Detection of exposure to environmental pesticides during pregnancy by the analysis of maternal hair using GC-MS. Chromatographia 2006 ; 64: 681-687.
18. 18 IPCS. The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2000-2002. Geneva: World Health Organization; 2002.
19. http://www.ciel.org/chemicals/pops-stockholm.html
20. Covaci A. Hura C. Gheorghe A. Neels H. Dirtu AC.. Organochlorine contaminants in hair of adolescents from Iassy, Romania. Chemosphere 2008 ; 72: 16-20.
21. Zhang H. Chai Z. Sun H.. Human hair as potential biomonitor for assessing persistent organic pollutants. Environ Int 2007 ; 33: 685-693.
22. Dauberschmit C. Wenning R.. Organochlorine pollutants in human hair. J Anal Toxicol 1998 ; 22: 610-611.