Fabrication of hydrophilic paclitaxel-loaded PLA-PEG-PLA microparticles via SEDS process

Frontiers of Materials Science in China

Volumn 3, Issue 1, 2009, Pages 15-24

  Ouyang, Ping ^a   Kang, Yun Qing ^a   Yin, Guang Fu ^a   Huang, Zhong Bing ^a   Yao, Ya Dong ^a   Liao, Xiao Ming ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Paclitaxel; PLA PEG PLA; SEDS; Supercritical CO2 (scCO2)

Indexed keywords

EID: 62249093755     PISSN: 16737377     EISSN: 16737482     Source Type: Journal    
DOI: 10.1007/s11706-009-0017-0     Document Type: Article

References (53)

1. E. K. Rowinsky R. C. Donehower 1995 Drug therapy-paclitaxel (Taxol) The New England Journal of Medicine 332 1004 1014
2. ®) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers Journal of Controlled Release 76 239 254
3. A. K. Singla A. Garg D. Aggarwal 2002 Paclitaxel and its formulations International Journal of Pharmaceutics 235 179 192
4. J. Wu Q. Liu R. J. Lee 2006 A folate receptor-targeted liposomal formulation for paclitaxel International Journal of Pharmaceutics 316 148 153
5. E. K. Park S. Y. Kim S. B. Lee 2005 Folate-conjugated methoxy poly (ethylene glycol)/poly(ε-caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery Journal of Controlled Release 109 158 168
6. K. H. Bae Y. Lee T. G. Park 2007 Oil-encapsulating PEO-PPO-PEO/PEG shell cross-linked nanocapsules for target-specific delivery of paclitaxel Biomacromolecules 8 650 656
7. Lee L Y, Smith K A, Wang C-H. Fabrication of micro and nanoparticles of paclitaxel-loaded poly-L-lactide for controlled release using supercritical antisolvent method: effects of thermodynamics and hydrodynamics. Molecular Engineering of Biological and Chemical Systems (MEBCS). Singapore-MIT Alliance (SMA), 2005, 17
8. S. H. Kim J. H. Jeong K. W. Chun 2005 Target-specific cellular uptake of PLGA nanoparticles coated with poly(L-lysine)-poly(ethylene glycol)-folate conjugate Langmuir 21 19 8852 8857
9. J. Mauduit N. Bukh M. Vert 1993 Gentamycin/poly(lactic acid) blends aimed at sustained release local antibiotic therapy administered per-operatively. I. The case of gentamycin base and gentamycin sulfate in poly(lactic acid) oligomers Journal of Controlled Release 23 3 209 220
10. Perrin D E, English J P. Handbook of Biodegradable Polymers, Chapter 1. Amsterdam: Harwood Academic, 1997
11. M. I. Llovet M. A. Egea J. Valero 1995 Methotrexate loaded nanoparticles: analysis of drug content and study of the matrix structure Drug Development and Industrial Pharmacy 21 15 1761 1771
12. S. A. Gomez-Lopera R. C. Plaza A. V. Delgado 2001 Synthesis and characterization of spherical magnetite/biodegradable polymer composite particles Journal of Colloid and Interface Science 240 40 47
13. K. H. Song C. H. Lee J. S. Lim 2002 Preparation of L-PLA particles by a continuous supercritical antisolvent precipitation process Korean Journal of Chemistry Engineering 19 1 139 145
14. P. Chan M. Kurisawa J. E. Chung 2007 Synthesis and characterization of chitosan-g-poly(ethylene glycol)-folate as a non-viral carrier for tumor-targeted gene delivery Biomaterials 28 540 549
15. H. S. Yoo T. G. Park 2004 Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate Journal of Controlled Release 100 247 256
16. X. B. Zhao R. J. Lee 2004 Tumor-selective targeted delivery of genes and antisense oligodeoxyribonucleotides via the folate receptor Advanced Drug Delivery Reviews 56 1193 1204
17. G. He L. L. Ma J. Pan 2007 ABA and BAB type triblock copolymers of PEG and PLA: A comparative study of drug release properties and "stealth" particle characteristics International Journal of Pharmaceutics 334 48 55
18. C. Hiemstra Z. Y. Zhong X. Jiang 2006 PEG-PLLA and PEG-PDLA multiblock copolymers: Synthesis and in situ hydrogel formation by stereocomplexation Journal of Controlled Release 116 e17 e19
19. H. D. Kim E. H. Bae I. C. Kwon 2004 Effect of PEG-PLLA diblock copolymer on macroporous PLLA scaffolds by thermally induced phase separation Biomaterials 25 2319 2329
20. J. Sun Z. Hong L. Yang 2004 Study on crystalline morphology of poly(L-lactide)-poly(ethylene glycol) diblock copolymer Polymer 45 5969 5977
21. W. C. Lai W. B. Liau T. T. Lin 2004 The effect of end groups of PEG on the crystallization behaviors of binary crystalline polymer blends PEG/PLLA Polymer 45 3073 3080
22. M. Rantakyla M. Jantti O. Aaltonen 2002 The effect of initial drop size on particle size in the supercritical antisolvent precipitation (SAS) technique The Journal of Supercritical Fluids 24 251 263
23. 2 and co-solvent The Journal of Supercritical Fluids 41 311 316
24. R. Ghaderi P. Artursson J. Carlfors 2000 A new method for preparing biodegradable microparticles and entrapment of hydrocortisone in DL-PLG microparticles using supercritical fluids European Journal of Pharmaceutical Sciences 10 1 9
25. R. Ghaderi P. Artursson J. Carlfors 1999 Preparation of biodegradable microparticles using solution enhanced dispersion by supercritical fluids (SEDS) Pharmaceutical Research 16 5 676 681
26. S. G. Kazarian 2000 Polymer processing with supercritical fluids Polymer Science, Series C 42 1 78 101
27. S. P. Nalawade F. Picchioni L. P. B. M. Janssen 2006 Supercritical carbon dioxide as a green solvent for processing polymer melts: Processing aspects and applications Progress in Polymer Science 31 1 19 43
28. J. A. Hyatt 1984 Liquid and supercritical carbon dioxide as organic solvents The Journal of Organic Chemistry 49 5097 5101
29. J. M. DeSimone Z. Guan C. S. Elsbernd 1992 Synthesis of fluoropolymers in supercritical carbon dioxide Science 257 945 947
30. A. A. Date V. B. Patravale 2004 Current strategies for engineering drug nanoparticles Current Opinion in Colloid & Interface Science 9 222 235
31. E. Reverchon G. D. Porta I. D. Rosa 2000 Supercritical antisolvent micronization of some biopolymers The Journal of Supercritical Fluids 18 239 245
32. P. York 1999 Strategies for particle design using supercritical fluid technologies Pharmaceutical Science & Technology Today 2 11 430 440
33. J. Jung M. Perrut 2001 Particle design using supercritical fluids: Literature and patent survey The Journal of Supercritical Fluids 20 179 219
34. S. D. Yeo E. Kiran 2005 Formation of polymer particles with supercritical fluids: A review The Journal of Supercritical Fluids 34 287 308
35. V. Majerik G. Charbit E. Badens 2007 Bioavailability enhancement of an active substance by supercritical antisolvent precipitation The Journal of Supercritical Fluids 40 101 110
36. 2 Macromolecular Rapid Communications 27 1254 1259
37. 2 Journal of Material Science: Material Medicine 18 2339 2345
38. Y. Wang R. N. Dave R. Pfeffer 2004 Polymer coating/encapsulation of nanoparticles using a supercritical anti-solvent process The Journal of Supercritical Fluids 28 85 99
39. Y. Wang R. Pfeffer R. N. Dave 2005 Polymer encapsulation of fine particles by a supercritical antisolvent process AIChE Journal 51 2 440 455
40. S. C. J. Loo C. P. Ooi Y. C. F. Boey 2004 Radiation effects on poly(lactide-co-glycolide) (PLGA) and poly(l-lactide) (PLLA) Polymer Degradation and Stability 83 259 265
41. W. Liu A. Yang Z. Li 2007 PEGylated PLGA nanoparticles as tumor ecrosis factor-α receptor blocking peptide carriers: preparation, characterization and release in vitro Journal of Wuhan University of Technology-Material Science Edition 22 1 112 116
42. D. Kubies F. Rypacek J. Kovarova 2000 Microdomain structure in polylactide-block-poly(ethylene oxide) copolymer films Biomaterials 21 529 536
43. Y. Dong S. S. Feng 2004 Methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs Biomaterials 25 2843 2849
44. J. Ren H. Hong T. Ren 2006 Preparation and characterization of magnetic PLA-PEG composite nanoparticles for drug targeting Reactive & Functional Polymers 66 944 951
45. Y. Chang Y. J. Shih R. C. Ruaan 2008 Preparation of poly(vinylidene fluoride) microfiltration membrane with uniform surface-copolymerized poly(ethylene glycol) methacrylate and improvement of blood compatibility Journal of Membrane Science 309 165 174
46. L. F. Zhang R. Sun L. Xu 2008 Hydrophilic poly (ethylene glycol) coating on PDLLA/BCP bone scaffold for drug delivery and cell culture Materials Science and Engineering: C 28 141 149
47. Gopferich A. Handbook of Biodegrable Polymers, Chapter 22. Amsterdam: OPA, 1997
48. S. Li H. Garreau M. Vert 1990 Structure-property relationships in the case of the degradation of massive poly(α-hydroxy acids) in aqueous media Journal of Materials Science: Materials in Medicine 1 4 198 206
49. P. Rokkanen O. Bostman E. Hirvensalo 2000 Totally biodegradable implants for bone fixation and ligament repair MRS Bulletin 25 1 21 24
50. T. Nakamura S. Hitomi S. Watanabe 1989 Bioabsorption of polylactides with different molecular properties Journal of Biomedical Materials Research 23 10 1115 1130
51. X. Zhang U. P. Wyss D. Pichora 1994 A mechanistic study of antibiotic release from biodegradable poly(d,1-lactide) cylinders Journal of Controlled Release 31 2 129 144
52. US Pharmacopeia. Organic Volatile Impurities, 25th Revision, 2002, 1943-1945
53. N. Elvassore A. Bertucco P. Caliceti 2001 Production of insulin-loaded poly(ethylene glycol)/poly(l-lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques Journal of Pharmaceutical Sciences 90 10 1628 1636