Is the host heme incorporated in microbial heme-proteins?

IUBMB Life

Volumn 61, Issue 1, 2009, Pages 80-83

  Tiburzi, Federica ^a   Imperi, Francesco ^a   Visca, Paolo ^a  

^a ROMA TRE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYTOCHROME; HEME; HEME ALBUMIN; HEME LIPOPROTEIN; HEME OXYGENASE; HEMOGLOBIN; HEMOPEXIN; HEMOPHORE; HEMOPROTEIN; IRON; METALLOPORPHYRIN; PORPHYRIN; REACTIVE OXYGEN METABOLITE; TRANSFERRIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; HEME PROTEIN, BACTERIA;

BACILLUS ANTHRACIS; BACILLUS SUBTILIS; BACTERIAL CELL; CELL DIFFERENTIATION; CELL MEMBRANE; CORYNEBACTERIUM DIPHTHERIAE; CYTOPLASM; ENZYME DEGRADATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; HEME SYNTHESIS; LISTERIA MONOCYTOGENES; NEISSERIA MENINGITIDIS; NONHUMAN; NOTE; PORPHYROMONAS GINGIVALIS; PROTEIN STABILITY; PROTEIN TARGETING; PROTEIN TRANSPORT; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; ARTICLE; BACTERIUM; BIOLOGICAL MODEL; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

BACTERIA; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; HEME; HEMEPROTEINS; IRON; MODELS, BIOLOGICAL;

EID: 62149152787     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.123     Document Type: Note

References (20)

1. Frankenberg, N., Moser, J., and Jahn, D. (2003) Bacterial heme biosynthesis and its biotechnological application. Appl. Microbiol. Biotechnol. 63, 115-127.
2. Furuyama, K., Kaneko, K., and Vargas, P. D. V. (2007) Heme as a magnificent molecule with multiple missions: heme determines its own fate and governs cellular homeostasis. Tohoku J. Exp. Med. 213, 1-16.
3. Sharp, P. and Srai, S. K. (2007) Molecular mechanisms involved in intestinal iron absorption. World J. Gastroenterol. 13, 4716-4724.
4. Stojiljkovic, I. and Perkins-Balding, D. (2002) Processing of heme and heme-containing proteins by bacteria. DNA Cell. Biol. 21, 281-295.
5. Otto, B. R., Verweij-van Vught, A. M., and MacLaren, D. M. (1992) Transferrins and heme-compounds as iron sources for pathogenic bacteria. Crit. Rev. Microbiol. 18, 217-233.
6. Ascenzi, P., Bocedi, A., Visca, P., Altruda, F., Tolosano, E., Beringhelli, T., and Fasano, M. (2005) Hemoglobin and heme scavenging. IUBMB Life 57, 749-1579
7. Wilks, A. and Burkhard, K. A. (2007) Heme and virulence: how bacterial pathogens regulate, transport and utilize heme. Nat. Prod. Rep. 24, 511-522.
8. Kikuchi, G., Yoshida, T., and Noguchi, M. (2005) Heme oxygenase and heme degradation. Biochem. Biophys. Res. Commun. 338, 558-567.
9. Ratliff, M., Zhu, W., Deshmukh, R., Wilks, A., and Stojiljkovic, I. (2001) Homologues of neisserial heme oxygenase in Gram-negative bacteria: degradation of heme by the product of the pigA gene of Pseudomonas aeruginosa. J. Bacteriol. 183, 6394-6403.
10. Reniere, M. L., Torres V. J., and Skaar, E. P. (2007). Intracellular metalloporphyrin metabolism in Staphylococcus aureus. Biometals 20, 333-345.
11. O'Brian, M. R. and Thöny-Meyer, L. (2002) Biochemistry, regulation and genomics of haem biosynthesis in prokaryotes. Adv. Microb. Physiol. 46, 257-318.
12. Parish, T., Schaeffer, M., Roberts, G., and Duncan, K. (2005) HemZ is essential for heme biosynthesis in Mycobacterium tuberculosis. Tuberculosis 85, 197-204.
13. Turner, P. C., Thomas, C. E., Elkins, C., Clary, S., and Sparling, P. F. (1998) Neisseria gonorrhoeae heme biosynthetic mutants utilize heme and hemoglobin as a heme source but fail to grow within epithelial cells. Infect. Immun. 66, 5215-5223.
14. Wyckoff, E. E., Schmitt, M., Wilks, A., and Payne, S. M. (2004) HutZ is required for efficient heme utilization in Vibrio cholerae. J. Bacteriol. 186, 4142-4151.
15. Schiött, T., Throne-Holst, M., and Hederstedt, L. (1997) Bacillus subtilis CcdA-defective mutants are blocked in a late step of cytochrome c biogenesis. J. Bacteriol. 179, 4523-4529.
16. Skaar, E. P., Humayun, M., Bae, T., DeBord, K. L., and Schneewind, O. (2004) Iron-source preference of Staphylococcus aureus infections. Science 305, 1626-1628.
17. von Wachenfeldt, C. and Hederstedt, L. (1990) Bacillus subtilis 13-kilodalton cytochrome c-550 encoded by cccA consists of a membraneanchor and a heme domain. J. Biol. Chem. 265, 13939-13948.
18. Friedman, D. B., Whitwell, C., Stauff, D., Pishchany, G., and Skaar, E. P. (2006) Staphylococcus aureus redirects central metabolism to increase iron availability. PLoS Pathog. 2, e87.
19. Stojiljkovic, I., Kumar, V., and Srinivasan, N. (1999) Non-iron metalloporphyrins: potent antibacterial compounds that exploit haem/Hb uptake systems of pathogenic bacteria. Mol. Microbiol. 31, 429-442.
20. Bozja, J., Yi, K., Shafer, W. M., and Stojiljkovic, I. (2004) Porphyrin based compounds exert antibacterial action against the sexually transmitted pathogens Neisseria gonorrhoeae and Haemophilus ducreyi. Int. J. Antimicrob. Agents 24, 578-584.