Anthranilic acid based CCK1 receptor antagonists: Blocking the receptor with the same 'words' of the endogenous ligand

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 6, 2009, Pages 2336-2350

  Lassiani, Lucia ^a   Pavan, Michela V ^a   Berti, Federico ^a   Kokotos, George ^b   Markidis, Theodoros ^b   Mennuni, Laura ^c   Makovec, Francesco ^c   Varnavas, Antonio ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF ATHENS   (Greece)

^c Rotta Research Laboratorium   (Italy)

Author keywords

Antagonists; Anthranilic acid; CCK; CCK1 R; Cholecystokinin; Ligands; Receptors

Indexed keywords

AMINO ACID; ANTHRANILIC ACID DERIVATIVE; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ A RECEPTOR ANTAGONIST; DIAMIDE; INDOLE; PHENYLALANINE; UNCLASSIFIED DRUG; VL 0395;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENANTIOMER; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTHRANILIC ACIDS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; RECEPTORS, CHOLECYSTOKININ; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 62149091115     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.02.012     Document Type: Article

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