Evaluation of beneficial effects of antioxidant properties of aqueous leaf extract of Andrographis paniculata in STZ-induced diabetes

Pakistan Journal of Pharmaceutical Sciences

Volumn 22, Issue 1, 2009, Pages 49-52

  Dandu, Anilkumar M ^a   Inamdar, Naseeruddin M ^a  

^a AL AMEEN COLLEGE OF PHARMACY   (India)

Author keywords

Andrographis; Antioxidant; Diabetes; Oxidative stress; Streptozotocin

Indexed keywords

ANDROGRAPHIS PANICULATA EXTRACT; BUFFER; CATALASE; CITRIC ACID; GLUCOSE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; ANTIDIABETIC AGENT; ANTIOXIDANT; PLANT EXTRACT;

ANDROGRAPHIS PANICULATA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HYPERGLYCEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; PH; PLANT LEAF; RAT; STREPTOZOCIN DIABETES; ANDROGRAPHIS; ANIMAL; BODY WEIGHT; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; LIVER; METABOLISM; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANDROGRAPHIS; ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; BODY WEIGHT; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; LIVER; MALE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 61949235620     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Kuyvenhoven JP and Meinders AE (1999). Oxidative stress and diabetes mellitus Pathogenesis of long-term complications. Eur. J. Intern. Med.,10: 9-19.
2. Kebapci N, Belgin EF, Fahrettin A, Emine S and Canan D (1999). Oxidative stress and antioxidant therapy in Type-2 diabetes mellitus. Turk. JEM., 4: 153-162.
3. Nedeljkovic ZS, Gokce N, Loscalzo J (2003). Mechanisms of oxidative stress and vascular dysfunction. Postgrad. Med. J., 79: 195-200. (Pubitemid 36605780)
4. Venkateswaran S and Pari L (2003). Effect of coccinia indica leaves on antioxidant status in streptozotocin induced diabetic rats. J Ethnopharmacol., 84: 163-168. (Pubitemid 36324254)
5. Farhangkhoee H, Khan AZ, Mukherjee S, Cukiernik M, Barbin PY, Karmazyn M and Chakrabarti S (2003). Heme oxygenase in diabetes induced oxidative stress in the heart. J. Mol. Cell. Cardiol., 35: 1439-1448. (Pubitemid 37491187)
6. Friedman J, Peleg E, Kagan K, Shnizer S and Rosenthal T (2003). Oxidative stress in hypertensive, diabetic and diabetic hypertensive rats. AJH. 16: 1049-1052. (Pubitemid 37500801)
7. Lipinski B (2001). Pathophysiology of oxidative stress in diabetes mellitus. J. diabetes. Complications.15: 203-210. (Pubitemid 33714181)
8. Zhao HY and Fang WV (1991). Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction. Clin. Med. J. (Engl), 104: 770-775.
9. Zhang XF and Tan BK (2000). Antihyperglycemic and antioxidant properties of Andrographis paniculata in normal and diabetic rats. Clin. Exp. Pharmacol. Physiol. 27: 358-363.
10. Wang DW and Zhao HY (1994). Prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis paniculata nees and fish oil. Clin. Med.J (Engl).107: 464-470.
11. Sinha KA (1972). Colorimetric assay of Catalase. Anal. Biochem. 47: 389-394.
12. Kakkar P, Dos B and Viswnathan PN (1984). A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem., 21: 130-132. (Pubitemid 15207169)
13. Noda Y, Kneyuki T, Igarashi T, Mori A and Packer L (2000). Antioxidant activity of nasunin, an anthocyanin in eggplant peels. Toxicology, 148: 119-123. (Pubitemid 30621351)
14. Laight DW, Carrier MJ and Anggard EE (2000). Antioxidants, diabetes and endothelial dysfunction. Cardiovasc. Res. 47: 457-464.
15. Kayamori F and Igarashi K (1994). Effects of dietary nasunin on the serum cholesterol levels in rats. Biosci. Biotechnol. Biochem, 58: 570-571.
16. Santhakumari P, Prakasam and Pugalendi KV (2003). Modulation of oxidative stress parameters by treatment with piper betel leaf in streptozotocin induced diabetic rats. Indian J. Pharmacol., 35: 373-378.