Modulation of oxidative stress parameters by treatment with Piper betle leaf in streptozotocin induced diabetic rats

Indian Journal of Pharmacology

Volumn 35, Issue 6, 2003, Pages 373-378

  Santhakumari, P ^a   Prakasam, A ^a   Pugalendi, K V ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidants; Diabetes mellitus; Lipid peroxidation

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETEL EXTRACT; CATALASE; GLIBENCLAMIDE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASSAY; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; ERYTHROCYTE; KIDNEY HOMOGENATE; LIPID PEROXIDATION; LIVER HOMOGENATE; MALE; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; PLASMA; POWDER; RAT; RAT STRAIN; SUPERNATANT; TISSUE LEVEL; VITAMIN BLOOD LEVEL;

EID: 0344665760     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Satyavati GV, Raina MK, Sharma M. Medicinal Plants of India. Vol. 1. New Delhi: Indian Council of Medical Research; 1976. p. 65-8.
2. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Ray C. Screening of Indian Plants for Biological Activity Part I. Indian J Exp Biol 1968;6:232-47.
3. Shukla R, Sharma SB, Puri D, Prabhu KM, Murthy PS. Medicinal plants for treatment of diabetes. Indian J Clin Biochem 2000;15:169-77.
4. The Wealth of India. The Dictionary of Indian Raw Materials and Industrial Products. Raw Material Vol. 5, Revised ed. New Delhi: Publication and information directorate, CSIR; 1992.
5. Chandra T, Sadigue J, Somasundaram S. Effect of Eclipta alba on inflammation and liver injury. Fitoterapia 1987;58:23-31.
6. National Institute of Health: "Guide for the Care and Use of Laboratory Animals", DHEW Publication (NIH), ed 2, Revised, Office of Science and Health Reports. Bethesda, USA: DRR/NIH; 1985.
7. Nichans WG Jr, Samuelson B. Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation. Br J Biochem 1968;6:126-30.
8. Jiang ZY, Hunt JV, Wolff SP. Ferrous ion oxidation in the presence of Xylenol orange for detection of lipid hydroxide in low-density lipoprotein. Anal Biochem 1992;202:384-9.
9. Rao JH, Kuether CA. Detection of ascorbic acid in whole blood and urine through the 2, 4 DNPH derivative of dehydroascorbic acid. J Biol Chem 1943;147:399-407.
10. Baker H, Frank O, De Angelis B, Reingold S: Plasma αtocopherol in man at various time interval after ingesting free or acetylated α-tocopherol. Nutr Res Int 1980;21:531-6.
11. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8.
12. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophysis 1959;2:70-7.
13. Kakkar P, Das B, Visvanathan PN. A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem 1972;197:588-90.
14. Sinha KA. Colorimetric assay of catalase. Anal Biochem 1972;47:389-94.
15. Rotruck JT, Pope AL, Ganther HE Selenium: Biochemical roles as a component of glutathione peroxidase. Science 1973;197:588-90.
16. Lowry OH, Rosenbroguh NJ, Farr AL, Randal RJ. Protein measurement with the Folin Phenol reagent. J Biol Chem 1965;193:256-75.
17. Karpen CW, Pritchard KA, Merola AJ, Ranganamala RV. Alterations of the prostaglandin-thromboxane ratio in streptozotocin induced diabetic rats. Prostagland Leukotrien Med 1982;8:93-103.
18. Nakakimura H., Mizuno K. Studies on lipid peroxidation in biological system II. Hyperlipoperoxidemia in mice induced by alloxan. Chem Pharm Bull 1980;28:2207-11.
19. Choudhary D., Kale RK. Antioxidant and non-toxic properties of Piper betle leaf extract: In vitro and in vivo studies. Phytother Res 2002;16:461-6.
20. Garg MC, Ojha S, Bansal OD. Antioxidant status of streptozotocin diabetic rats. Indian J Exp Med 1996;34:264-6.
21. Niki E, Noguchi N, Tsuchihashi H, Gotoh N. Interaction among vitamin C, vitamin E and beta-carotene. Am J Clin Nutr 1995;62:13228-68.
22. Takenaka Y, Miki M, Yasuda H, Mino M. The effect of alphatocopherol as an antioxidant on the oxidation of membrane protein thiols induced by free radicals generated in different sites. Arch Biochem Biophys 1991;285:344-50.
23. Arivazhagan P, Thilagavathy T, Pannerselvam C. Antioxidant lipoate and tissue antioxidants in aged rats. J Nutr Biochem 2000;11:122-7.
24. Cheng LEW, Kellogg III, Packer L. Photoactivation of catalase. Photochem Photobiol 1981;34:125-9.
25. Searle AJ, Wilson RL. Glutathione peroxidase: Effect of superoxide, hydroxyl and bromine free radicals on enzyme activity. Int J Rad Biol 1981;34:125-9.
26. Illing EKB, Gray CH, Lawrence RD. Blood glutathione and non-glucose reducing substance in diabetes. Biochem J 1991;48:637.