Relative analgesic potencies of levobupivacaine and ropivacaine for caudal anesthesia in children

Anesthesia and Analgesia

Volumn 108, Issue 3, 2009, Pages 805-813

  Ingelmo, Pablo ^a   Ingelmo, Geoffc ^a   Astuto, Marinella ^b   Duffy, Chris ^b   Donath, Susan ^c   Disma, Nicola ^d   Rosano, Giuseppe ^a   Fumagalli, Roberto ^a   Gullo, Antonio ^a  

^a Department of Perioperative Medicine and Intensive   (Italy)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHIROCAINA; CODEINE; FENTANYL; LEVOBUPIVACAINE; LONARID; NAROPINA; PARACETAMOL; ROPIVACAINE; SEVOFLURANE; UNCLASSIFIED DRUG; AMIDE; BUPIVACAINE; LOCAL ANESTHETIC AGENT;

ARTICLE; CAUDAL ANESTHESIA; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG POTENCY; HUMAN; MALE; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; CONGENITAL MALFORMATION; INFANT; INGUINAL HERNIA; MOVEMENT (PHYSIOLOGY); PAIN ASSESSMENT; PHYSIOLOGY; PREMEDICATION; PRESCHOOL CHILD; REGRESSION ANALYSIS; TESTIS; TREATMENT OUTCOME;

AMIDES; ANESTHESIA, CAUDAL; ANESTHETICS, LOCAL; BUPIVACAINE; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HERNIA, INGUINAL; HUMANS; INFANT; MALE; MOVEMENT; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PREANESTHETIC MEDICATION; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; TESTIS; TREATMENT OUTCOME;

EID: 61949118519     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e3181935aa5     Document Type: Article

References (30)

1. Dixon WJ. Staircase bioassay: the up-and-down method. Neurosci Biobehav Rev 1991;15:47-50
2. Polley LS, Columb MO, Naughton NN, Wagner DS, van de Ven CJ. Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labor: implications for therapeutic indexes. Anesthesiology 1999;90:944-50
3. Lyons G, Columb MO, Wilson RC, Johnson RV. Epidural pain relief in labour: potencies of levobupivacaine and racemic bupivacaine. Br J Anaesth 1998;81:899-901
4. Polley LS, Columb MO, Naughton NN, Wagner DS, Van de Ven CJ, Goralsky KH. Relative analgesic potencies of Levobupivacaine and ropivacaine for epidural analgesia in labor. Anesthesiology 2003;99:1354-8
5. Benhamou D, Ghosh C, Mercier F. A randomized sequential allocation study to determine the minimum effective analgesic concentration of levobupivacaine and ropivacaine in patients receiving epidural analgesia for Labor. Anesthesiology 2003;99:1383-6
6. Lacassie H, Columb M, Lacassie H, Lantadilla R. The relative motor blocking potencies of epidural bupivacaine and ropivacaine in labor. Anesth Analg 2002;95:204-8
7. Lacassie H, Columb M. The relative motor blocking properties of bupivacaine and levobupivacaine in labor. Anesth Analg 2003;97:1509-13
8. Deng XM, Xiao WJ, Tang GZ, Luo MP, Xu KL. The minimum local anesthetic concentration of ropivacaine for caudal analgesia in children. Anesth Analg 2002;94:1465-8
9. Astuto M, Disma N, Arena C. Levobupivacaine 0,25% compared with ropivacaine 0,25% by caudal route in children. Eur J Anesthiol 2003;20:826-30
10. Breschan C, Jost R, Krumpholz R, Schaumberger F, Stettner H, Marhofer P. A prospective study comparing the analgesic efficacy of levobupivacaine, ropivacaine and bupivacaine in pediatric patients undergoing caudal blockade. Paediatr Anaesth 2005;15:301-6
11. Ivani G, De Negri P, Lonnqvist PA, L'Erario M, Mossetti V, DiFilippo A, Rosso F. Caudal anaesthesia for minor pediatric surgery: a prospective randomized comparison of ropivacaine 0.2% vs levobupivacaine 0.2%. Paediatr Anaesth 2005;15:491-4
12. Frawley G, Downie S, Huang GH. Levobupivacaine caudal anesthesia in children: a randomized double-blind comparison with bupivacaine. Paediatr Anaesth 2006;16:754-60
13. Ingelmo PM, Locatelli BG, Sonzogni V, Gattoni C, Cadisco A, Lorini M, Sora GN. Caudal 0.2% ropivacaine is less effective during operation than 0.2% levobupivacaine and 0.2% bupivacaine: a double-blind, randomised, controlled trial. Paediatr Anaesth 2006;16:955-61
14. Stewart J, Kellett N, Castro D. The central nervous system and cardiovascular effects of levobupivacaine and ropivacaine in healthy volunteers. Anesth Analg 2003;97:412-26
15. Mazoit JX. Pharmacokinetic/pharmacodynamics modeling of anaesthetics in children. Pediatr Drugs 2006;8:139-50
16. Buttner W, Finke W. Analysis of behavioural and physiological Parameters for the assessment of postoperative analgesic demand in Newborns, infants and young children. Paediatr Anaesth 2000;10:199-204
17. Aguirre FT, Garcia R, Nava-Ocampo A. Dose response of ropivacaine administered caudally to children undergoing surgical procedures under sedation with midazolam. Clin Exp Pharmacol Physiol 2004;31:462-5
18. Khalil S, Campos C, Farag A Vije H, Ritchey M, Chuang A. Caudal block in children. Ropivacaine compared with bupivacaine. Anesthesiology 1999;91:1279-84
19. Bosenberg A, Thomas J, Lopez T, Huledal G, Jeppsson L, Larsson LE. Plasma concentrations of ropivacaine following a single shot caudal block of 1, 2, or 3 mg/kg in children. Acta Anesthesiol Scand 2001;45:1276 - 80
20. Ivani G, De Negri P, Lonnqvist PA, Eksborg S, Mossetti V, Grosssetti R, Italiano S, Rosso F, Tonetti F, Copipietro L. A comparison of three different concentrations of levobupivacaine for caudal block in children. Anesth Analg 2003;97:368-71
21. Da Conceicao M, Coelho L, Khalil M. Ropivacaine 0.25% compared with bupivacaine 0.25% by the caudal route. Paediatr Anaesth 1999;9:229-33
22. Khalil S, Lingadevaru H, Bolos M Rabb M, Matuszczak M, Mapusa D, Chuang A. Caudal regional anesthesia, ropivacaine concentration, postoperative analgesia and infants. Anesth Analg 2006;102:395-9
23. Luz G, Innerhofer P, Haussler B, Oswald E, Salner E, Sparr H. Comparison of ropivacaine 0.1% and 0.25 with bupivacaine 0.25 for single shot caudal anesthesia in children. Paediatr Anaesth 2000;10:499-504
24. Ivani G, Lampugnani E, Torre M, Calevo Maria G, DeNegri P, Borrometi F, Messeri A, Calamendrei M, Lonnquist PA, Morton NS. Comparison of ropivacaine and bupivacaine for paediatric caudal block. Br J Anaesth 1998;81:247-48
25. Ingelmo PM, Fumagalli R. Central blocks with levobupivacaine in children. Minerva Anestesiol 2005;71:339-45
26. Locatelli B, Ingelmo P, Sonzogni V, Zanella A, Gatti V, Spotti A, DiMarco S, Fumagalli R. Randomized, double blind phase III, controlled trial comparing levobupivacaine 0.25%, ropivacaine 0.25% and bupivacaine 0.25% by the caudal route in children. Br J Anaesth 2005;94:366 -71
27. Ivani G, De Negri P, Conio A, Grossetti R, Vitale P, Vercellino C, Gagliardi F, Eksborg S. Comparison of racemic bupivacaine, ropivacaine, and levobupivacaine for pediatric caudal anaesthesia: effect on postoperative analgesia and motor block. Reg Anaesth Pain Med 2002;27:157-61
28. Koinig H, Krenn C, Glaser C, Marhofer P, Wilding E, Brunner M, Wallner T, Grabner C, Klimscha W, Semsroth M. The dose response of caudal ropivacaine in children. Anesthesiology 1999;90:1339-44
29. Pace N, Stylianou M. Advances in and limitations of up- and -down methodology. Anesthesiology 2007;1:144-52
30. Vagero M, Sundberg R. The distribution of the maximum likelihood estimator in up and down experiments for quantal dose response data. J Biopharm Stat 1999;9:499 -519