Supranormal electroretinogram in a 10-year-old girl with lead toxicity

Documenta Ophthalmologica

Volumn 118, Issue 2, 2009, Pages 163-166

  Nagpal, Agnieszka G ^a   Brodie, Scott E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Electroretinogram; Lead toxicity; Supranormal ERG

Indexed keywords

LEAD;

ARTICLE; CASE REPORT; CHILD; CLINICAL FEATURE; COGNITION; COLOR VISION; ELECTRORETINOGRAM; EYE DISEASE; EYE REFRACTION; FEMALE; HUMAN; LEAD BLOOD LEVEL; LEAD POISONING; NIGHT VISION; PHOTOPIC VISION; RESPONSE TIME; SCHOOL CHILD; STEREOSCOPIC VISION; VISUAL ACUITY;

CHILD; COLOR VISION; DEPTH PERCEPTION; ELECTRORETINOGRAPHY; EYE; FEMALE; HUMANS; LEAD; LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD; PERCEPTUAL DISORDERS; REACTION TIME; VISUAL ACUITY;

EID: 61849172863     PISSN: 00124486     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10633-008-9144-7     Document Type: Article

References (12)

1. Lidsky TI, Schneider JS (2003) Lead neurotoxicity in children: Basic mechanisms and clinical correlates. Brain 126(1):5-19. doi: 10.1093/ brain/awg014
2. Jacobs DE, Clickner RP, Zhou JY et al (2002) The prevalence of lead-based paint hazards in U.S. housing. Environ Health Perspect 110(10):A599-A606
3. Su M, Barrueto F, Hoffman RS (2002) Childhood lead poisoning from paint chips: A continuing problem. J Urban Health 79(4):491-501. doi: 10.1093/ jurban/79.4.491
4. Otto DA, Fox DA (1993) Auditory and visual dysfunction following lead exposure. Neurotoxicology 14(2-3):191-207
5. Rothenberg SJ, Schnaas L, Salgado-Valladares M et al (2002) Increased ERG a- and b-wave amplitudes in 7- to 10-year-old children resulting from prenatal lead exposure. Invest Ophthalmol Vis Sci 43(6):2036-2044
6. Fox DA, Campbell ML, Blocker YS (1997) Functional alterations and apoptotic cell death in the retina following developmental or adult lead exposure. Neurotoxicology 18(3):645-664
7. Fox DA, Kal SV, Hamilton WR, Johnson JE, O'Callaghan JP (2008) Low-level human equivalent gestational lead exposure produces supernormal scotopic electroretinograms, increased retinal neurogenesis, and decreased retinal dopamine utilization in rats. Environ Health Perspect 116(5):618-625
8. Lilienthal H, Kohler K, Turfeld M et al (1994) Persistent increases in scotopic B-wave amplitudes after lead exposure in monkeys. Exp Eye Res 59(2):203-209. doi: 10.1006/exer.1994.1098
9. Heckenlively JR, Nusinowitz S (2006) Hyperabnormal (supranormal) electroretinographic responses. In: Heckenlively JR, Arden GB (eds) Principles and practice of clinical electrophysiology of vision, 2nd edn. The MIT Press, Cambridge, MA, pp 533-540
10. Carr RE, Siegel IM (1982) Visual electrodiagnostic testing a practical guide for the clinician. Baltimore, Williams and Wilkins, p 77
11. Tanabe J, Shirao Y, Oda N et al (1992) Evaluation of retinal integrity in eyes with retained intraocularmetallic foreign body by ERG and EOG. Documenta Ophthalmologica 79:71-78
12. Conradi NG, Sjöström A, Gustafsson B, Wigström H (1990) Decreased nerve conduction velocity in optic nerve following early post-natal low-dose lead exposure. Acta Physiol Scand 140(4):515-519