Low-level human equivalent gestational lead exposure produces supernormal scotopic electroretinograms, increased retinal neurogenesis and decreased retinal dopamine utilization in rats

Environmental Health Perspectives

Volumn 116, Issue 5, 2008, Pages 618-625

  Fox, Donald A ^a,b,c   Kala, Subbarao V ^d   Hamilton, W Ryan ^b   Johnson, Jerry E ^e   O'Callaghan, James P ^f  

^a UNIVERSITY OF HOUSTON   (United States)

^b University of Houston   (United States)

^c UNIVERSITY OF HOUSTON   (United States)

^d One Source Toxicological Laboratory Inc   (United States)

^e UNIVERSITY OF HOUSTON DOWNTOWN   (United States)

^f NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Bipolar cells; Development; Dopamine; Electroretinograms; Gestation; Lead; Neurogenesis; Rod photoreceptors; Scotopic; Zinc

Indexed keywords

BIOLOGICAL MARKER; DOPAMINE; LEAD; ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL LOSS; CELL MATURATION; CONTROLLED STUDY; DOPAMINE METABOLISM; ELECTRORETINOGRAPHY; FEMALE; GESTATIONAL AGE; GESTATIONAL LEAD EXPOSURE; LEAD BLOOD LEVEL; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NEWBORN; NIGHT VISION; NONHUMAN; PERINATAL PERIOD; PHOTORECEPTOR CELL; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; RETINA DEVELOPMENT; RETINA ROD; SIGNAL TRANSDUCTION; TERATOLOGY; ZINC BLOOD LEVEL;

ANIMALS; DARK ADAPTATION; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRORETINOGRAPHY; ENVIRONMENTAL EXPOSURE; FEMALE; LEAD POISONING; MATERNAL EXPOSURE; MODELS, ANIMAL; PHOTORECEPTORS; PREGNANCY; RATS; RATS, LONG-EVANS; RETINA;

ANIMALIA; RATTUS;

EID: 45749152968     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.11268     Document Type: Article

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