-
2
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T, Elmore SW, Shoemaker AR, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature. 2005;435:677-681.
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
-
3
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft MF, Wei AH, Mason KD, et al. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell. 2006;10:389-399.
-
(2006)
Cancer Cell
, vol.10
, pp. 389-399
-
-
van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
-
4
-
-
0033619265
-
-
De Maria R, ZeunerA, Eramo A, et al. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature. 1999;401:489-493.
-
De Maria R, ZeunerA, Eramo A, et al. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature. 1999;401:489-493.
-
-
-
-
5
-
-
0032950951
-
Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis
-
De Maria R, Testa U, Luchetti L, et al. Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis. Blood. 1999;93:796-803.
-
(1999)
Blood
, vol.93
, pp. 796-803
-
-
De Maria, R.1
Testa, U.2
Luchetti, L.3
-
6
-
-
0033529506
-
Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines
-
Silva M, Benito A, Sanz C, et al. Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines. J Biol Chem. 1999;274:22165-22169.
-
(1999)
J Biol Chem
, vol.274
, pp. 22165-22169
-
-
Silva, M.1
Benito, A.2
Sanz, C.3
-
7
-
-
0038644834
-
Stem cell factor protects erythroid precursor cells from che-motherapeutic agents via up-regulation of BCL-2 family proteins
-
Zeuner A, Pedini F, Signore M, et al. Stem cell factor protects erythroid precursor cells from che-motherapeutic agents via up-regulation of BCL-2 family proteins. Blood. 2003;102:87-93.
-
(2003)
Blood
, vol.102
, pp. 87-93
-
-
Zeuner, A.1
Pedini, F.2
Signore, M.3
-
8
-
-
0033168769
-
GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression
-
Gregory T, Yu C, MaA, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression. Blood. 1999;94:87-96.
-
(1999)
Blood
, vol.94
, pp. 87-96
-
-
Gregory, T.1
Yu, C.2
Ma, A.3
Orkin, S.H.4
Blobel, G.A.5
Weiss, M.J.6
-
9
-
-
0030854080
-
The roles of Bcl-X(L) and apopain in the control of erythropoiesis by erythropoietin
-
Gregoli PA, Bondurant MC. The roles of Bcl-X(L) and apopain in the control of erythropoiesis by erythropoietin. Blood. 1997;90:630-640.
-
(1997)
Blood
, vol.90
, pp. 630-640
-
-
Gregoli, P.A.1
Bondurant, M.C.2
-
10
-
-
0032568003
-
Expression of Bcl-x in erythroid precursors from patients with polycythemia vera
-
Silva M, Richard C, Benito A, Sanz C, Olalla I, Fernandez-Luna JL. Expression of Bcl-x in erythroid precursors from patients with polycythemia vera. N Engl J Med. 1998;338:564-571.
-
(1998)
N Engl J Med
, vol.338
, pp. 564-571
-
-
Silva, M.1
Richard, C.2
Benito, A.3
Sanz, C.4
Olalla, I.5
Fernandez-Luna, J.L.6
-
11
-
-
17844383458
-
Aunique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couedic JP, et al. Aunique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005; 434:1144-1148.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
-
12
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365: 1054-1061.
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
-
13
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387-397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
14
-
-
20744460045
-
Identification of an acquired JAK2 mutation in polycythemia vera
-
Zhao R, Xing S, Li Z, et al. Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem. 2005;280:22788-22792.
-
(2005)
J Biol Chem
, vol.280
, pp. 22788-22792
-
-
Zhao, R.1
Xing, S.2
Li, Z.3
-
15
-
-
33646414171
-
Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells
-
Zeuner A, Pedini F, Signore M, et al. Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells. Blood. 2006;107:3495-3502.
-
(2006)
Blood
, vol.107
, pp. 3495-3502
-
-
Zeuner, A.1
Pedini, F.2
Signore, M.3
-
16
-
-
0030953788
-
The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells
-
Sakai I, Kraft AS. The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells. J Biol Chem. 1997;272: 12350-12358.
-
(1997)
J Biol Chem
, vol.272
, pp. 12350-12358
-
-
Sakai, I.1
Kraft, A.S.2
-
17
-
-
33646406275
-
Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders
-
Passamonti F, Rumi E, Pietra D, et al. Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders. Blood. 2006;107:3676-3682.
-
(2006)
Blood
, vol.107
, pp. 3676-3682
-
-
Passamonti, F.1
Rumi, E.2
Pietra, D.3
-
18
-
-
41349123507
-
BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia
-
Del Gaizo Moore V, Schlis KD, Sallan SE, Armstrong SA, Letai A. BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia. Blood. 2008;111:2300-2309.
-
(2008)
Blood
, vol.111
, pp. 2300-2309
-
-
Del Gaizo Moore, V.1
Schlis, K.D.2
Sallan, S.E.3
Armstrong, S.A.4
Letai, A.5
-
19
-
-
33750628289
-
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
-
KonoplevaM, Contractor R, TsaoT, et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell. 2006;10:375-388.
-
(2006)
Cancer Cell
, vol.10
, pp. 375-388
-
-
Konopleva, M.1
Contractor, R.2
Tsao, T.3
-
20
-
-
42149113415
-
Anovel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells
-
Vogler M, Dinsdale D, Sun XM, et al. Anovel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells. Cell Death Differ. 2008;15:820-830.
-
(2008)
Cell Death Differ
, vol.15
, pp. 820-830
-
-
Vogler, M.1
Dinsdale, D.2
Sun, X.M.3
|