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Volumn 156, Issue 1, 2009, Pages 141-148

Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation

Author keywords

cell transplantation; Autoimmunity; Cytotoxic T cell; Islets of Langerhans; Type 1 diabetes

Indexed keywords

C PEPTIDE; HLA ANTIGEN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 61849097838     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03812.x     Document Type: Article
Times cited : (37)

References (38)
  • 1
    • 0035076928 scopus 로고    scopus 로고
    • Lessons learned from more than 1,000 pancreas transplants at a single institution
    • Sutherland DE, Gruessner RW, Dunn DL et al. Lessons learned from more than 1,000 pancreas transplants at a single institution. Ann Surg 2001 233 : 463 501.
    • (2001) Ann Surg , vol.233 , pp. 463-501
    • Sutherland, D.E.1    Gruessner, R.W.2    Dunn, D.L.3
  • 2
    • 0033526637 scopus 로고    scopus 로고
    • Effect of simultaneous pancreas-kidney transplantation on mortality of patients with type-1 diabetes mellitus and end-stage renal failure
    • Smets YF, Westendorp RG, van der Pijl JW et al. Effect of simultaneous pancreas-kidney transplantation on mortality of patients with type-1 diabetes mellitus and end-stage renal failure. Lancet 1999 353 : 1915 9.
    • (1999) Lancet , vol.353 , pp. 1915-9
    • Smets, Y.F.1    Westendorp, R.G.2    Van Der Pijl, J.W.3
  • 3
    • 19944404750 scopus 로고    scopus 로고
    • Islet transplantation: Progress and challenge
    • Gaglia JL, Shapiro AM, Weir GC. Islet transplantation: progress and challenge. Arch Med Res 2005 36 : 273 80.
    • (2005) Arch Med Res , vol.36 , pp. 273-80
    • Gaglia, J.L.1    Shapiro, A.M.2    Weir, G.C.3
  • 4
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JR, Ryan EA et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000 343 : 230 8.
    • (2000) N Engl J Med , vol.343 , pp. 230-8
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3
  • 5
    • 6844239526 scopus 로고    scopus 로고
    • Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: Graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft
    • Keymeulen B, Ling Z, Gorus FK et al. Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. Diabetologia 1998 41 : 452 9.
    • (1998) Diabetologia , vol.41 , pp. 452-9
    • Keymeulen, B.1    Ling, Z.2    Gorus, F.K.3
  • 6
    • 10744219939 scopus 로고    scopus 로고
    • Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody
    • Hering BJ, Kandaswamy R, Harmon JV et al. Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody. Am J Transplant 2004 4 : 390 401.
    • (2004) Am J Transplant , vol.4 , pp. 390-401
    • Hering, B.J.1    Kandaswamy, R.2    Harmon, J.V.3
  • 8
    • 33751228149 scopus 로고    scopus 로고
    • Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft
    • Keymeulen B, Gillard P, Mathieu C et al. Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft. Proc Natl Acad Sci USA 2006 103 : 17444 9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17444-9
    • Keymeulen, B.1    Gillard, P.2    Mathieu, C.3
  • 9
    • 21344462346 scopus 로고    scopus 로고
    • Five-year follow-up after clinical islet transplantation
    • Ryan EA, Paty BW, Senior PA et al. Five-year follow-up after clinical islet transplantation. Diabetes 2005 54 : 2060 9.
    • (2005) Diabetes , vol.54 , pp. 2060-9
    • Ryan, E.A.1    Paty, B.W.2    Senior, P.A.3
  • 10
    • 38549143599 scopus 로고    scopus 로고
    • Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts
    • Gillard P, Ling Z, Mathieu C et al. Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts. Transplantation 2008 85 : 256 63.
    • (2008) Transplantation , vol.85 , pp. 256-63
    • Gillard, P.1    Ling, Z.2    Mathieu, C.3
  • 11
    • 0035960583 scopus 로고    scopus 로고
    • Posttransplantation diabetes mellitus in FK-506-treated renal transplant recipients: Analysis of incidence and risk factors
    • Maes BD, Kuypers D, Messiaen T et al. Posttransplantation diabetes mellitus in FK-506-treated renal transplant recipients: analysis of incidence and risk factors. Transplantation 2001 72 : 1655 61.
    • (2001) Transplantation , vol.72 , pp. 1655-61
    • Maes, B.D.1    Kuypers, D.2    Messiaen, T.3
  • 12
    • 0033979599 scopus 로고    scopus 로고
    • Nephrotoxicity of immunosuppressive drugs: Long-term consequences and challenges for the future
    • de Mattos AM, Olyaei AJ, Bennett WM. Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. Am J Kidney Dis 2000 35 : 333 46.
    • (2000) Am J Kidney Dis , vol.35 , pp. 333-46
    • De Mattos, A.M.1    Olyaei, A.J.2    Bennett, W.M.3
  • 13
    • 0344613988 scopus 로고    scopus 로고
    • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
    • Li Y, Li XC, Zheng XX, Wells AD, Turka LA, Strom TB. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance. Nat Med 1999 5 : 1298 302.
    • (1999) Nat Med , vol.5 , pp. 1298-302
    • Li, Y.1    Li, X.C.2    Zheng, X.X.3    Wells, A.D.4    Turka, L.A.5    Strom, T.B.6
  • 14
    • 0345118182 scopus 로고    scopus 로고
    • Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil
    • van Gelder T, ter Meulen CG, Hene R, Weimar W, Hoitsma A. Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil. Transplantation 2003 75 : 788 91.
    • (2003) Transplantation , vol.75 , pp. 788-91
    • Van Gelder, T.1    Ter Meulen, C.G.2    Hene, R.3    Weimar, W.4    Hoitsma, A.5
  • 15
    • 42449104351 scopus 로고    scopus 로고
    • MTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes
    • Fraenkel M, Ketzinel-Gilad M, Ariav Y et al. mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes 2008 57 : 945 57.
    • (2008) Diabetes , vol.57 , pp. 945-57
    • Fraenkel, M.1    Ketzinel-Gilad, M.2    Ariav, Y.3
  • 16
    • 33750583959 scopus 로고    scopus 로고
    • Sirolimus is associated with reduced islet engraftment and impaired beta-cell function
    • Zhang N, Su D, Qu S et al. Sirolimus is associated with reduced islet engraftment and impaired beta-cell function. Diabetes 2006 55 : 2429 36.
    • (2006) Diabetes , vol.55 , pp. 2429-36
    • Zhang, N.1    Su, D.2    Qu, S.3
  • 17
    • 34250160238 scopus 로고    scopus 로고
    • Immunotherapy with antibodies to protect beta cells in type i diabetic pancreas transplant recipients
    • van de Linde P, van de Boog P, Tysma OMH et al. Immunotherapy with antibodies to protect beta cells in type I diabetic pancreas transplant recipients. Clin Exp Immunol 2007 149 : 56 62.
    • (2007) Clin Exp Immunol , vol.149 , pp. 56-62
    • Van De Linde, P.1    Van De Boog, P.2    Tysma, O.M.H.3
  • 18
    • 0037164337 scopus 로고    scopus 로고
    • Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy
    • Swanson SJ, Hale DA, Mannon RB et al. Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy. Lancet 2002 360 : 1662 4.
    • (2002) Lancet , vol.360 , pp. 1662-4
    • Swanson, S.J.1    Hale, D.A.2    Mannon, R.B.3
  • 19
    • 43049150180 scopus 로고    scopus 로고
    • Cellular islet autoimmunity associates with clinical outcome of islet transplantation
    • Huurman VAL, Hilbrands R., Pinkse GGM et al. Cellular islet autoimmunity associates with clinical outcome of islet transplantation. PLoS ONE 2008 3 : e2435.
    • (2008) PLoS ONE , vol.3 , pp. 2435
    • Huurman, V.A.L.1    Hilbrands, R.2    Pinkse, G.G.M.3
  • 20
    • 0032971910 scopus 로고    scopus 로고
    • Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients
    • Roep BO, Stobbe I, Duinkerken G et al. Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients. Diabetes 1999 48 : 484 90.
    • (1999) Diabetes , vol.48 , pp. 484-90
    • Roep, B.O.1    Stobbe, I.2    Duinkerken, G.3
  • 21
    • 22144445286 scopus 로고    scopus 로고
    • Alloreactivity against repeated HLA mismatches of sequential islet grafts transplanted in non-uremic type 1 diabetes patients
    • van Kampen CA, van de Linde P, Duinkerken G et al. Alloreactivity against repeated HLA mismatches of sequential islet grafts transplanted in non-uremic type 1 diabetes patients. Transplantation 2005 80 : 118 26.
    • (2005) Transplantation , vol.80 , pp. 118-26
    • Van Kampen, C.A.1    Van De Linde, P.2    Duinkerken, G.3
  • 22
    • 29044447424 scopus 로고    scopus 로고
    • Allogeneic MHC class i molecules with numerous sequence differences do not elicit a CTL response
    • Heemskerk MB, Roelen DL, Dankers MK et al. Allogeneic MHC class I molecules with numerous sequence differences do not elicit a CTL response. Hum Immunol 2005 66 : 969 76.
    • (2005) Hum Immunol , vol.66 , pp. 969-76
    • Heemskerk, M.B.1    Roelen, D.L.2    Dankers, M.K.3
  • 23
    • 33744732773 scopus 로고    scopus 로고
    • Feasibility, safety, and efficacy of percutaneous transhepatic injection of beta-cell grafts
    • Maleux G, Gillard P, Keymeulen B et al. Feasibility, safety, and efficacy of percutaneous transhepatic injection of beta-cell grafts. J Vasc Interv Radiol 2005 16 : 1693 7.
    • (2005) J Vasc Interv Radiol , vol.16 , pp. 1693-7
    • Maleux, G.1    Gillard, P.2    Keymeulen, B.3
  • 24
    • 0038316560 scopus 로고    scopus 로고
    • Laparoscopic approach for human islet transplantation into a defined liver segment in type-1 diabetic patients
    • Movahedi B, Keymeulen B, Lauwers MH, Goes E, Cools N, Delvaux G. Laparoscopic approach for human islet transplantation into a defined liver segment in type-1 diabetic patients. Transplant Int 2003 16 : 186 90.
    • (2003) Transplant Int , vol.16 , pp. 186-90
    • Movahedi, B.1    Keymeulen, B.2    Lauwers, M.H.3    Goes, E.4    Cools, N.5    Delvaux, G.6
  • 25
    • 0028987253 scopus 로고
    • T-cell reactivity to beta-cell membrane antigens associated with beta-cell destruction in IDDM
    • Roep BO, Kallan AA, Duinkerken G et al. T-cell reactivity to beta-cell membrane antigens associated with beta-cell destruction in IDDM. Diabetes 1995 44 : 278 83.
    • (1995) Diabetes , vol.44 , pp. 278-83
    • Roep, B.O.1    Kallan, A.A.2    Duinkerken, G.3
  • 26
    • 0027074872 scopus 로고
    • Determination of cytotoxic T-lymphocyte precursor frequencies using europium labeling as a nonradioactive alternative to labeling with chromium-51
    • Bouma GJ, van der Meer-Prins PM, van Bree FP, van Rood JJ, Claas FH. Determination of cytotoxic T-lymphocyte precursor frequencies using europium labeling as a nonradioactive alternative to labeling with chromium-51. Hum Immunol 1992 35 : 85 92.
    • (1992) Hum Immunol , vol.35 , pp. 85-92
    • Bouma, G.J.1    Van Der Meer-Prins, P.M.2    Van Bree, F.P.3    Van Rood, J.J.4    Claas, F.H.5
  • 27
    • 0024163626 scopus 로고
    • Computer aided design and evaluation of limiting and serial dilution experiments
    • Strijbosch LW, Does RJ, Buurman WA. Computer aided design and evaluation of limiting and serial dilution experiments. Int J Biomed Comput 1988 23 : 279 90.
    • (1988) Int J Biomed Comput , vol.23 , pp. 279-90
    • Strijbosch, L.W.1    Does, R.J.2    Buurman, W.A.3
  • 28
    • 0037446716 scopus 로고    scopus 로고
    • Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling
    • Hu H, Dong Y, Feng P, Fechner J, Hamawy M, Knechtle SJ. Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling. Transplantation 2003 75 : 1075 7.
    • (2003) Transplantation , vol.75 , pp. 1075-7
    • Hu, H.1    Dong, Y.2    Feng, P.3    Fechner, J.4    Hamawy, M.5    Knechtle, S.J.6
  • 29
    • 20044380331 scopus 로고    scopus 로고
    • Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion
    • Pearl JP, Parris J, Hale DA et al. Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion. Am J Transplant 2005 5 : 465 74.
    • (2005) Am J Transplant , vol.5 , pp. 465-74
    • Pearl, J.P.1    Parris, J.2    Hale, D.A.3
  • 30
    • 20844453233 scopus 로고    scopus 로고
    • Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells
    • Lee YR, Yang IH, Lee YH et al. Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells. Blood 2005 105 : 3951 5.
    • (2005) Blood , vol.105 , pp. 3951-5
    • Lee, Y.R.1    Yang, I.H.2    Lee, Y.H.3
  • 31
    • 38449111857 scopus 로고    scopus 로고
    • Calcineurin inhibitors block MHC-restricted antigen presentation in vivo
    • Lee YH, Lee YR, Im SA et al. Calcineurin inhibitors block MHC-restricted antigen presentation in vivo. J Immunol 2007 179 : 5711 6.
    • (2007) J Immunol , vol.179 , pp. 5711-6
    • Lee, Y.H.1    Lee, Y.R.2    Im, S.A.3
  • 32
    • 33750892406 scopus 로고    scopus 로고
    • Tacrolimus treatment of plasmacytoid dendritic cells inhibits dinucleotide (CpG-)-induced tumour necrosis factor-alpha secretion
    • Naranjo-Gómez M, Climent N, Cos J et al. Tacrolimus treatment of plasmacytoid dendritic cells inhibits dinucleotide (CpG-)-induced tumour necrosis factor-alpha secretion. Immunology 2006 119 : 488 98.
    • (2006) Immunology , vol.119 , pp. 488-98
    • Naranjo-Gómez, M.1    Climent, N.2    Cos, J.3
  • 33
    • 0026770627 scopus 로고
    • Evidence that antibody formation against a certain HLA alloantigen is associated not with a quantitative but with a qualitative change in the cytotoxic T cells recognizing the same antigen
    • Roelen D, Datema G, van Bree S, Zhang L, van Rood J, Claas F. Evidence that antibody formation against a certain HLA alloantigen is associated not with a quantitative but with a qualitative change in the cytotoxic T cells recognizing the same antigen. Transplantation 1992 53 : 899 903.
    • (1992) Transplantation , vol.53 , pp. 899-903
    • Roelen, D.1    Datema, G.2    Van Bree, S.3    Zhang, L.4    Van Rood, J.5    Claas, F.6
  • 34
    • 0028297159 scopus 로고
    • IgG antibodies against an HLA antigen are associated with activated cytotoxic T cells against this antigen, IgM are not
    • Roelen DL, van Bree S, Witvliet MD et al. IgG antibodies against an HLA antigen are associated with activated cytotoxic T cells against this antigen, IgM are not. Transplantation 1994 57 : 1388 92.
    • (1994) Transplantation , vol.57 , pp. 1388-92
    • Roelen, D.L.1    Van Bree, S.2    Witvliet, M.D.3
  • 35
  • 36
    • 33750033626 scopus 로고    scopus 로고
    • Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: Relevance for islet transplantation
    • Cantaluppi V, Biancone L, Romanazzi GM et al. Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation. Am J Transplant 2006 6 : 2601 11.
    • (2006) Am J Transplant , vol.6 , pp. 2601-11
    • Cantaluppi, V.1    Biancone, L.2    Romanazzi, G.M.3
  • 37
    • 33746368487 scopus 로고    scopus 로고
    • Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells
    • Battaglia M, Stabilini A, Draghici E et al. Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells. Diabetes 2006 55 : 1571 80.
    • (2006) Diabetes , vol.55 , pp. 1571-80
    • Battaglia, M.1    Stabilini, A.2    Draghici, E.3
  • 38
    • 32644473626 scopus 로고    scopus 로고
    • Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance
    • Battaglia M, Stabilini A, Draghici E et al. Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. Diabetes 2006 55 : 40 9.
    • (2006) Diabetes , vol.55 , pp. 40-9
    • Battaglia, M.1    Stabilini, A.2    Draghici, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.