Improved outcome in Wegener's granulomatosis and microscopic polyangiitis? A retrospective analysis of 95 cases in two cohorts

Journal of Internal Medicine

Volumn 265, Issue 4, 2009, Pages 496-506

  Eriksson, P ^a,b   Jacobsson, L ^c   Lindell, A ^d   Nilsson, J A ^c   Skogh, T ^b  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d Department of Clinical Immunology and Transfusion Medicine   (Sweden)

Author keywords

Anti neutrophil cytoplasmic antibodies; Microscopic polyangitiis; Patient survival; Standardized mortality ratio; Wegener's granulomatosis

Indexed keywords

CREATININE; CYCLOPHOSPHAMIDE; PREDNISOLONE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE SEVERITY; DRUG DOSE REDUCTION; FEMALE; HUMAN; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALE; MICROSCOPIC POLYANGIITIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RELAPSE; STANDARDIZED MORTALITY RATIO; SURVIVAL RATE; WEGENER GRANULOMATOSIS;

COHORT STUDIES; CYCLOPHOSPHAMIDE; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INCIDENCE; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; SWEDEN; VASCULITIS; WEGENER GRANULOMATOSIS;

EID: 61849092685     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2008.02060.x     Document Type: Article

References (47)

1. Fauci A, Wolff S. Wegener's granulomatosis: studies in eighteen patients and a review of the literature. Medicine (Baltimore) 1973 52 : 535 61.
2. Fauci A, Haynes B, Katz P, Wolff S. Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med 1983 98 : 76 85.
3. Walton EW. Giant-cell granuloma of the respiratory tract (Wegener's granulomatosis). BMJ 1958 2 : 561 5.
4. Little M, Nazar L, Farrington K. Outcome in glomerulonephritis due to systemic small vessel vasculitis: effect of functional status and non-vasculitic comorbidity. Nehprol Dial Transplant 2004 19 : 356 64.
5. Reinhold-Keller E, Beuge N, Latza U et al. An interdisciplinary approach to the care of patients with Wegener's granulomatosis: long-term outcome in 155 patients. Arthritis Rheum 2000 43 : 1021 32.
6. Luqmani R, Bacon P, Beaman M et al. Classical versus non-renal Wegener's granulomatosis. Q J Med 1994 87 : 161 7.
7. Wilkowski M, Velosa J, Holley K et al. Risk factors in idiopathic renal vasculitis and glomerulonephritis. Kidney Int 1989 36 : 1133 41.
8. McLaughlin K, Jerimiah P, Fox J et al. Has the prognosis for patients with pauci-immune necrotizing glomerulonephritis improved? Nephrol Dial Transplant 1998 13 : 1696 701.
9. Aasarod K, Iversen B, Hammerstrom J et al. Wegener's granulomatosis: clinical course in 108 patients with renal involvement. Nephrol Dial Transplant 2000 15 : 611 8.
10. Mahr A, Girard T, Agher R, Guillevin L. Analysis of factors predictive of survival based on 49 patients with systemic Wegener's granulomatosis and prospective follow-up. Rheumatology 2001 40 : 492 8.
11. Koldingsnes W, Nossent H. Predictors of survival and organ damage in Wegener′s granulomatosis. Rheumatology 2002 41 : 572 81.
12. Hogan S, Nachman P, Wilkman A, Jennette JC, Falk RJ. Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol 1996 7 : 23 32.
13. Cohen B, Clark W. Pauci-immune renal vasculitis: natural history, prognostic factors, and impact of therapy. Am J Kidney Dis 2000 36 : 914 24.
14. Matteson E, Gold K, Bloch D, Hunder G. Long-term survival of patients with Wegener's granulomatosis from the American College of Rheumatology Wegener's granulomatosis classification criteria cohort. Am J Med 1996 101 : 129 34.
15. Segelmark M, Elzouki A-N, Wieslander J. The PiZ gene of a1-antitrypsin as a determinant of outcome in PR3-ANCA-positive vasculitis. Kidney Int 1995 48 : 844 50.
16. Harper L, Savage CO. ANCA-associated renal vasculitis at the end of the twentieth century - a disease of older patients. Rheumatology 2005 44 : 495 501.
17. Westman K, Selga D, Isberg P-E, Bladström A, Olsson H. High proteinase 3-anti-neutrophil cytoplasmic antibody (ANCA) level measured by the capture enzyme-linked immunosorbent assay method is associated with decreased patient survival in ANCA-associated vasculitis with renal involvement. J Am Soc Nephrol 2003 14 : 2926 33.
18. Gordon M, Luqmani R, Adu D et al. Relapses in patients with systemic vascultis. Q J Med 1993 86 : 779 89.
19. Anderson G, Coles E, Crane M et al. Wegener's granuloma: a series of 265 British cases seen between 1975 and 1985. A reort by a sub-committee of the British Thoracic Society research Committtee. Q J Med 1992 83 : 427 43.
20. Luqmani R, Exley A, Kitas G, Bacon P. Disease assessment and management of the vasculitides. Baillieres Clin Rheumatol 1997 11 : 423 44.
21. Jenette J, Falk R, Andrassy K et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum 1994 37 : 187 92.
22. Jayne D, Rasmussen N. Treatment of antineutrophil cytoplasm autoantibody-associated systemic vasculitis: initiatives of the European Community systemic vasculitis clinical trials study group. Mayo Clin Proc 1997 72 : 737 47.
23. Eriksson P. Nine patients with anti-neutrophil cyoplasmic antibody-positive vasculitis successfully treated with rituximab. J Intern Med 2005 257 : 540 8.
24. Lane SE, Watts RA, Shepstone L, Scott DG. Primary systemic vasculitis: clinical features and mortality. Q J Med 2005 98 : 97 111.
25. Booth A, Almond K, Burns A et al. Outcome of ANCA-associated renal vasculitis: a 5-year retrospective analysis. Am J Kidney Dis 2003 41 : 776 84.
26. Andrassy K, Erb A, Koderisch J et al. Wegener's granulomatosis with renal involvement: patient survival and correlations between initial renal function, renal histology, therapy and renal outcome. Clin Nephrol 1991 35 : 139 47.
27. Bakoush O, Segelmark M, Torffvit O, Ohlsson S, Tencer J. Urine IgM excretion predicts outcome in ANCA-associated renal vasculitis. Nephrol Dial Transplant 2006 21 : 1263 9.
28. Brijker F, Magee C, Tervaert JWC, O'Neill S, Walshe J. Outcome analysis of patients with vasculitis associated with antineutrophil cytoplasmic antibodies. Clin Nephrol 1999 52 : 344 51.
29. Chen M, Yu F, Zhang Y, Zhao M. Clinical and pathological characteristics of Chinese patients with antineutrophil cytoplasmaic autoantibody associated systemic vasculitides: a study of 426 patients from a single centre. Postgrad Med J 2005 81 : 723 7.
30. Franssen C, Gans R, Arends B et al. Differences between anti-myeloperoxidase- and anti-proteinase 3-associated renal disease. Kidney Int 1995 47 : 193 9.
31. Gans R, Kuizinga M, Goldschmeding R et al. Clinical features and outcome in patients with glomerulonephritis and antineutrophil cytoplasmic autoantibodies. Nephron 1993 64 : 182 8.
32. Garrett PJ, Dewhurst AG, Morgan LS, Mason JC, Dathan JR. Renal disease associated with circulating anitneutrophil cytoplasm activity. Q J Med 1992 306 : 731 49.
33. Guilllevin L, Cordier J, Lhote F et al. A prospective, multicenter, randomized trial comparing steroids and pulse cyclophosphamide versus steroids and oral cyclophosphamide in the treatment of generalized Wegener's granulomatosis. Arthritis Rheum 1997 40 : 2187 98.
34. Guillevin L, Durand-Gasselin B, Cevallos R et al. Microscopic polyangiitis. Arthritis Rheum 1999 42 : 421 30.
35. Krafcik SS, Covin R, Lynch J, Sitrin R. Wegener′s granulomatosis in the elderly. Chest 1996 109 : 430 7.
36. MacIsaac AI, Moran JE, Davies DJ, Murphy BF, Georgiou T, Niall JF. Antineutrophil cytoplasm atnibody (ANCA) associated vasculitis. Clin Nephrol 1990 34 : 5 8.
37. Pettersson E, Sundelin B, Heigl Z et al. Incidence and outcome of pauci-immune necrotizing and crescentic glomerulonephritis in adults. Clin Nephrol 1995 43 : 141 9.
38. Rihova Z, Jancova E, Merta M et al. Long-term outcome of patients with antineutrophil cytoplasmic autoantibody-associated vasculitis with renal involvement. Kidney Blood Press Res 2005 28 : 144 52.
39. Slot M, Tervaert JWC, Franssen C, Stegeman C. Renal survival and prognostic factors in patients with PR3-ANCA associated vasculitis with renal involvement. Kidney Int 2003 63 : 670 7.
40. Vassallo M, Shepherd RJ, Iqbal P, Feehally J. Age-related variations in presentation and outcome in Wegener's granulomatosis. J R Coll Physicians Lond 1997 31 : 396 400.
41. Weidner S, Geuss S, Hafezi-Rachti S, Wonka A, Rupprecht H. ANCA-associated vasculitis with renal involvement: an outcome analysis. Nephrol Dial Transplant 2004 19 : 1403 11.
42. Watts RA, Lane SE, Bentham G, Scott DG. Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. Arthritis Rheum 2000 43 : 414 9.
43. Westman K, Bygren P, Olsson H, Ranstam J, Wieslander J. Relapse rate, renal survival and cancer morbidity in patients with Wegener's granulomatosis or microscopic poyangiitis with renal involvement. J Am Soc Nephrol 1998 9 : 842 52.
44. Watts RA, Gonzalez-Gay MA, Lane SE, Garcia-Porrua C, Bentham G, Scott DG. Geoepidemiology of systemic vasculitis: comparison of the incidence in two regions in Europe. Ann Rheum Dis 2001 60 : 170 2.
45. Koldingsnes W, Nossent H. Epidemiology of Wegener's granulomatosis in northern Norway. Arthritis Rheum 2000 43 : 2481 7.
46. Knight A, Ekbom A, Brandt L, Askling J. Increasing incidence of Wegener's granulomatosis in Sweden. J Rheumatol 2006 33 : 2060 3.
47. Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M. Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churge-Strauss syndrome within a defined population in southern Sweden. Rheumatology (Oxford) 2007 46 : 1329 37.