-
1
-
-
33745530860
-
The many paths to p38 mitogen-activated protein kinase activation in the immune system
-
Ashwell J.D. The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat. Rev. Immunol. 6 (2006) 532-540
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 532-540
-
-
Ashwell, J.D.1
-
2
-
-
0142026209
-
P38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
-
Kumar S., Boehm J., and Lee J.C. P38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat. Rev. Drug Discov. 2 (2003) 717-726
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 717-726
-
-
Kumar, S.1
Boehm, J.2
Lee, J.C.3
-
3
-
-
34249331264
-
Novel strategies for inhibition of the p38 MAPK pathway
-
Zhang J., Shen B., and Lin A. Novel strategies for inhibition of the p38 MAPK pathway. Trends Pharmacol. Sci. 28 (2007) 286-295
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, pp. 286-295
-
-
Zhang, J.1
Shen, B.2
Lin, A.3
-
4
-
-
34248372929
-
Macrophage glucocorticoid receptors regulate Toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase
-
Bhattacharyya S., Brown D.E., Brewer J.A., Vogt S.K., and Muglia L.J. Macrophage glucocorticoid receptors regulate Toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase. Blood 109 (2007) 4313-4319
-
(2007)
Blood
, vol.109
, pp. 4313-4319
-
-
Bhattacharyya, S.1
Brown, D.E.2
Brewer, J.A.3
Vogt, S.K.4
Muglia, L.J.5
-
5
-
-
27944461325
-
Generation and characterization of p38beta (MAPK11) gene-targeted mice
-
Beardmore V.A., Hinton H.J., Eftychi C., Apostolaki M., Armaka M., Darragh J., McIlrath J., Carr J.M., Armit L.J., Clacher C., Malone L., Kollias G., and Arthur J.S. Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol. Cell. Biol. 25 (2005) 10454-10464
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10454-10464
-
-
Beardmore, V.A.1
Hinton, H.J.2
Eftychi, C.3
Apostolaki, M.4
Armaka, M.5
Darragh, J.6
McIlrath, J.7
Carr, J.M.8
Armit, L.J.9
Clacher, C.10
Malone, L.11
Kollias, G.12
Arthur, J.S.13
-
6
-
-
20244365497
-
P38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
-
Sabio G., Arthur J.S., Kuma Y., Peggie M., Carr J., Murray-Tait V., Centeno F., Goedert M., Morrice N.A., and Cuenda A. P38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. EMBO J. 24 (2005) 1134-1145
-
(2005)
EMBO J.
, vol.24
, pp. 1134-1145
-
-
Sabio, G.1
Arthur, J.S.2
Kuma, Y.3
Peggie, M.4
Carr, J.5
Murray-Tait, V.6
Centeno, F.7
Goedert, M.8
Morrice, N.A.9
Cuenda, A.10
-
7
-
-
34249334506
-
p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway
-
Hui L., Bakiri L., Mairhorfer A., Schweifer N., Haslinger C., Kenner L., Komnenovic V., Scheuch H., Beug H., and Wagner E.F. p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat. Genet. 39 (2007) 741-749
-
(2007)
Nat. Genet.
, vol.39
, pp. 741-749
-
-
Hui, L.1
Bakiri, L.2
Mairhorfer, A.3
Schweifer, N.4
Haslinger, C.5
Kenner, L.6
Komnenovic, V.7
Scheuch, H.8
Beug, H.9
Wagner, E.F.10
-
8
-
-
34249807348
-
p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation
-
Ventura J.J., Tenbaum S., Perdiguero E., Huth M., Guerra C., Barbacid M., Pasparakis M., and Nebreda A.R. p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation. Nat. Genet. 39 (2007) 750-758
-
(2007)
Nat. Genet.
, vol.39
, pp. 750-758
-
-
Ventura, J.J.1
Tenbaum, S.2
Perdiguero, E.3
Huth, M.4
Guerra, C.5
Barbacid, M.6
Pasparakis, M.7
Nebreda, A.R.8
-
9
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cuenda A., Rouse J., Doza Y.N., Meier R., Cohen P., Gallagher T.F., Young P.R., and Lee J.C. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364 (1995) 229-233
-
(1995)
FEBS Lett.
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
Meier, R.4
Cohen, P.5
Gallagher, T.F.6
Young, P.R.7
Lee, J.C.8
-
10
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee J.C., Laydon J.T., McDonnell P.C., Gallagher T.F., Kumar S., Green D., McNulty D., Blumenthal M.J., Heys J.R., and Landvatter S.W. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372 (1994) 739-746
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
11
-
-
0035863103
-
Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells
-
Lin H., Chen C., and Chen B.D. Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells. Biochem. J. 353 (2001) 299-306
-
(2001)
Biochem. J.
, vol.353
, pp. 299-306
-
-
Lin, H.1
Chen, C.2
Chen, B.D.3
-
12
-
-
0035038286
-
STAT3 exerts two-way regulation in the biological effects of IL-6 in M1 leukemia cells
-
Zhang J., Shen B., Li Y., and Sun Y. STAT3 exerts two-way regulation in the biological effects of IL-6 in M1 leukemia cells. Leukoc. Res. 25 (2001) 463-472
-
(2001)
Leukoc. Res.
, vol.25
, pp. 463-472
-
-
Zhang, J.1
Shen, B.2
Li, Y.3
Sun, Y.4
-
13
-
-
32044463169
-
Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain
-
Zhang J., Bui T.N., Xiang J., and Lin A. Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain. Mol. Cell. Biol. 26 (2006) 1223-1234
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1223-1234
-
-
Zhang, J.1
Bui, T.N.2
Xiang, J.3
Lin, A.4
-
14
-
-
19644367000
-
Activation and signaling of the p38 MAP kinase pathway
-
Zarubin T., and Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Res. 15 (2005) 11-18
-
(2005)
Cell Res.
, vol.15
, pp. 11-18
-
-
Zarubin, T.1
Han, J.2
-
15
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M., Chen W., and Cobb M.H. Differential regulation and properties of MAPKs. Oncogene 26 (2007) 3100-3112
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
16
-
-
44949201263
-
CAMP modulates macrophage development by suppressing M-CSF-induced MAPKs activation
-
Zhu N., Cui J., Qiao C., Li Y., Ma Y., Zhang J., and Shen B. CAMP modulates macrophage development by suppressing M-CSF-induced MAPKs activation. Cell Mol. Immunol. 5 (2008) 153-157
-
(2008)
Cell Mol. Immunol.
, vol.5
, pp. 153-157
-
-
Zhu, N.1
Cui, J.2
Qiao, C.3
Li, Y.4
Ma, Y.5
Zhang, J.6
Shen, B.7
-
17
-
-
32044447243
-
The JNK are important for development and survival of macrophages
-
Himes S.R., Sester D.P., Ravasi T., Cronau S.L., Sasmono T., and Hume D.A. The JNK are important for development and survival of macrophages. J. Immunol. 176 (2006) 2219-2228
-
(2006)
J. Immunol.
, vol.176
, pp. 2219-2228
-
-
Himes, S.R.1
Sester, D.P.2
Ravasi, T.3
Cronau, S.L.4
Sasmono, T.5
Hume, D.A.6
-
18
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., Leisten J.C., Motiwala A., Pierce S., Satoh Y., Bhagwat S.S., Manning A.M., and Anderson D.W. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. USA 98 (2001) 13681-13686
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
Bhagwat, S.S.11
Manning, A.M.12
Anderson, D.W.13
-
19
-
-
0025893822
-
Macrophages in haemopoietic and other tissues of the developing mouse detected by the monoclonal antibody F4/80
-
Morris L., Graham C.F., and Gordon S. Macrophages in haemopoietic and other tissues of the developing mouse detected by the monoclonal antibody F4/80. Development 112 (1991) 517-526
-
(1991)
Development
, vol.112
, pp. 517-526
-
-
Morris, L.1
Graham, C.F.2
Gordon, S.3
-
20
-
-
0026750568
-
Synergism of interleukin 6 and 1 alpha, 25-dihydroxyvitamin D3 in induction of myeloid differentiation of human leukemic cell lines
-
Duits A.J., Dimjati W., van de Winkel J.G., and Capel P.J. Synergism of interleukin 6 and 1 alpha, 25-dihydroxyvitamin D3 in induction of myeloid differentiation of human leukemic cell lines. J. Leukoc. Biol. 51 (1992) 237-243
-
(1992)
J. Leukoc. Biol.
, vol.51
, pp. 237-243
-
-
Duits, A.J.1
Dimjati, W.2
van de Winkel, J.G.3
Capel, P.J.4
-
21
-
-
0037210389
-
Overexpression of the c-fos gene perturbs functional maturation of M1 cells into macrophages
-
Obata S., Okada S., Ohkubo Y., Murasawa M., Hatano M., Sekiya S., and Tokuhisa T. Overexpression of the c-fos gene perturbs functional maturation of M1 cells into macrophages. Mol. Immunol. 39 (2003) 585-594
-
(2003)
Mol. Immunol.
, vol.39
, pp. 585-594
-
-
Obata, S.1
Okada, S.2
Ohkubo, Y.3
Murasawa, M.4
Hatano, M.5
Sekiya, S.6
Tokuhisa, T.7
-
22
-
-
0033548164
-
Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation
-
Rausch O., and Marshall C.J. Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation. J. Biol. Chem. 274 (1999) 4096-4105
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 4096-4105
-
-
Rausch, O.1
Marshall, C.J.2
-
23
-
-
0037370472
-
Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway
-
Wang J.M., Lai M.Z., and Yang-Yen H.F. Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Mol. Cell. Biol. 23 (2003) 1896-1909
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 1896-1909
-
-
Wang, J.M.1
Lai, M.Z.2
Yang-Yen, H.F.3
-
24
-
-
0031410504
-
Immunoglobulin superfamily proteins: structure, mechanisms, and drug discovery
-
Huang Z., Li S., and Korngold R. Immunoglobulin superfamily proteins: structure, mechanisms, and drug discovery. Biopolymers 43 (1997) 367-382
-
(1997)
Biopolymers
, vol.43
, pp. 367-382
-
-
Huang, Z.1
Li, S.2
Korngold, R.3
-
25
-
-
0030715563
-
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2
-
Iotsova V., Caamano J., Loy J., Yang Y., Lewin A., and Bravo R. Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. Nat. Med. 3 (1997) 1285-1289
-
(1997)
Nat. Med.
, vol.3
, pp. 1285-1289
-
-
Iotsova, V.1
Caamano, J.2
Loy, J.3
Yang, Y.4
Lewin, A.5
Bravo, R.6
-
26
-
-
0033592288
-
Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents In vivo expression of proinflammatory genes
-
Liu S.F., Ye X., and Malik A.B. Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents In vivo expression of proinflammatory genes. Circulation 100 (1999) 1330-1337
-
(1999)
Circulation
, vol.100
, pp. 1330-1337
-
-
Liu, S.F.1
Ye, X.2
Malik, A.B.3
-
27
-
-
0035379555
-
Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38
-
Madrid L.V., Mayo M.W., Reuther J.Y., and Baldwin Jr. A.S. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276 (2001) 18934-18940
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18934-18940
-
-
Madrid, L.V.1
Mayo, M.W.2
Reuther, J.Y.3
Baldwin Jr., A.S.4
-
28
-
-
2342429684
-
PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation
-
Sawka-Verhelle D., Escoubet-Lozach L., Fong A.L., Hester K.D., Herzig S., Lebrun P., and Glass C.K. PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation. J. Biol. Chem. 279 (2004) 17772-17784
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17772-17784
-
-
Sawka-Verhelle, D.1
Escoubet-Lozach, L.2
Fong, A.L.3
Hester, K.D.4
Herzig, S.5
Lebrun, P.6
Glass, C.K.7
|