First Y-type actinomycins from Streptomyces with divergent structure-activity relationships for antibacterial and cytotoxic properties

Organic and Biomolecular Chemistry

Volumn 7, Issue 3, 2009, Pages 444-450

  Bitzer, Jens ^a   Streibel, Martin ^a   Langer, Hans Jörg ^a   Grond, Stephanie ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPROLINES; AMINO ACID PATTERNS; ANTIBACTERIAL EFFECTS; CYTOTOXIC; RING CLOSURES; STREPTOMYCES SP; STRUCTURAL MOTIFS; STRUCTURE ACTIVITY RELATIONSHIPS; THREONINE RESIDUES;

AMINES; AMINO ACIDS; BIOACTIVITY; BIOCERAMICS; CHLORINE; CHROMOPHORES; ORGANIC ACIDS;

AMINATION;

STREPTOMYCES; STREPTOMYCES SP.;

AMINO ACID; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CYTOTOXIN; DACTINOMYCIN;

ARTICLE; BACTERIUM; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECT; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

AMINO ACIDS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; CELL LINE, TUMOR; CYTOTOXINS; DACTINOMYCIN; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 61749099953     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b815689a     Document Type: Article

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