Bone marrow-derived stromal cells (BMSCs) interact with fibroblasts in accelerating wound healing

Journal of Investigative Surgery

Volumn 21, Issue 5, 2008, Pages 270-279

  Dulchavsky, Deborah ^a   Gao, Xiaohua ^a   Liu, Yong Bo ^a   Deeb, Dorrah ^a   Arbab, Ali S ^a   McIntosh, Kevin ^b   Dulchavsky, Scott A ^a   Gautam, Subhash C ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

^b Department of Diagnostic Radiology ^*  (United States)

Author keywords

Cell migration; Fibroblasts; Mesenchymal stem cells; Wound closure; Wound healing

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; BONE MARROW; BONE MARROW DERIVED STROMAL CELL; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; CULTURE MEDIUM; FASCIA DISEASE; FIBROBLAST; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN INJURY; STRENGTH; STROMA CELL; WOUND HEALING; ANIMAL; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL LINE; COCULTURE; DISEASE MODEL; FASCIA; IN VITRO STUDY; INJURY; PATHOLOGY; PHYSIOLOGY; SECRETION; SKIN; SPRAGUE DAWLEY RAT; TRANSPLANTATION;

CHEMOTACTIC FACTOR;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL LINE; CELL PROLIFERATION; CHEMOTACTIC FACTORS; CHEMOTAXIS; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; FASCIA; FIBROBLASTS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SKIN; STROMAL CELLS; WOUND HEALING;

EID: 61749089564     PISSN: 08941939     EISSN: 15210553     Source Type: Journal    
DOI: 10.1080/08941930802216831     Document Type: Article

References (36)

1. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143-147.
2. Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature. 2001;410:701-705.
3. Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science. 1997;276:71-74.
4. Yoon YS, Lee N, Scadova H. Myocardial regeneration with bone marrow-derived stem cells. Biol Cell. 2005;97:253-263.
5. Haynesworth SE, Baber MA, Caplan AI. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha. J Cellular Physiol. 1996;166:585-592.
6. Takai K, Hara J, Matsumoto K, et al. Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis. Blood. 1997;89:1560-1565.
7. Chen X, Li Y, Wang L, et al. Ischemic rat brain extracts induce human marrow stromal cell growth factor production. Neuropath. 2002;22:275-279.
8. Chopp M, Li Y. Treatment of neural injury with marrow stromal cells. Lancet Neurol. 2002;1:92-100.
9. Orlic D, Kajstura J, Chimenti S, et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA. 2001;98:10344-10349.
10. Horowitz EM, Prockop DJ, Fitzpatrick LA, et al. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nature Med. 1999;5:309-313.
11. Steeper RA. Critical review of the aetiology of diabetic neuropathic ulcers. J Wound Care. 2005;14:101-103.
12. Zimny S, Pfohl M. Healing times and prediction of wound healing in neuropathic diabetic foot ulcers: a prospective study. Exp Clin Endocrinol Diabetes. 2005;113:90-93.
13. Gomez NJ. Wound care management in the end-stage renal disease population. Adv Ren Replace Ther. 1997;4:390-396.
14. Sieggreen MY, Kline RA. Recognizing and managing venous leg ulcers. Adv Skin Wound Care. 2004;17:302-311.
15. Ferguson MK. The effect of antineoplastic agents on wound healing. Surg Gynecol Obstet. 1985;154:421-429.
16. Anstead GM. Steroids, retinoids, and wound healing. Adv Wound Care. 1998;11:277-285.
17. Loots MA, Lamme EN, Zeegelaar J, et al. Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds. J Invest Dermatol. 1998;111:850-857.
18. Pierce GF, Tarpley JE, Allman RM, et al. Tissue repair processes in healing chronic pressure ulcers treated with recombinant platelet-derived growth factor BB. Am J Pathol. 1994;145:399-410.
19. Steed DL. Modifying the wound healing response with exogenous growth factors. Clin Plast Surg. 1998;25:397-405.
20. Heng BC, Liu H, Cao T. Transplanted human embryonic stem cells as biological "catalysts" for tissue repair and regeneration. Med Hypotheses. 2005;64:1085-1088.
21. Robson MC, Phillips LG, Thomason A, et al. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. Lancet. 1992;339:23-25.
22. Bennett SP, Griffiths GD, Schor AM, et al. Growth factors in the treatment of diabetic foot ulcers. Br J Surg. 2003;90:133-146.
23. McFarlin K, Gao X, Liu YB, et al. Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rats. Wound Rep Reg. 2006;14:471-478.
24. Kwon DS, Gao X, Liu YB, et al. Treatment with bone marrow-derived stromal cells accelerate wound healing in rats. Int Wound J. 2008;5:453-463.
25. Okumura N, Tsuji K, Ebihara Y, et al. Chemotactic and chemokinetic activities of stem cell factor on murine hematopoietic progenitor cells. Blood. 1996;87:4100-4108.
26. Badiavas EV, Abedi M, Butmarc J, et al. Participation of bone marrow-derived cells in cutaneous wound healing. J Cell Physiol. 2003;196:245-250.
27. Badiavas EV, Falanga V. Treatment of chronic wounds with bone marrow-derived cells. Arch Dermatol. 2003;139:510-516.
28. Yamaguchi Y, Kubo T, Murakami T, et al. Bone marrow cells differentiate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing. Br J Dermatol. 2005;152:616-622.
29. Majumdar MK, Keane-Moore M, Buyaner D, et al. Characterization and functionality of cell surface molecules on human mesenchymal stem cells. J Biomed Sci. 2003;10:228-241.
30. Archambault MP, McIntosh KR, Duty A, et al. Allogeneic rat mesenchymal stem cells do not elicit an immune response after implantation in immunocompetent recipients [abstract]. Blood. 2003;96:762a.
31. Tse WT, Pendleton JD, Beyer WM, et al. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation. 2003;75:389-397.
32. Singer AJ, Clark RAF. Cutaneous wound healing. New Eng J Med. 1999;341:738-746.
33. Buckmire MA, Parquet G, Greenway S, et al. Temporal expression of TGF-β1, EGF, and PDGF-BB in a model of colonic wound healing. J Surg Res. 1998;80:52-57.
34. Bennett NT, Schultz GS. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg. 1993;165:728-734.
35. Liu Y, Dulchavsky DS, Gao X, et al. Wound repair by bone marrow stromal cells through growth factor production. J Surg Res. 2006;136:336-341.
36. Brittan M, Braun KM, Reynolds LE, et al. Bone marrow cell engraft within the epidermis and proliferate in vivo with no evidence of cell fusion. J Pathol. 2005;205:1-13.