Wound Repair by Bone Marrow Stromal Cells through Growth Factor Production

Journal of Surgical Research

Volumn 136, Issue 2, 2006, Pages 336-341

  Liu, Yongbo ^a   Dulchavsky, Deborah S ^a   Gao, Xiaohua ^a   Kwon, David ^a   Chopp, Michael ^b   Dulchavsky, Scott ^a   Gautam, Subhash C ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

^b HENRY FORD HOSPITAL   (United States)

Author keywords

bone marrow stromal cells; EGF, VEGF; growth factors; TGF ; wound healing

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; INTERLEUKIN 1ALPHA; KERATINOCYTE GROWTH FACTOR; LIPOPOLYSACCHARIDE; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL FUNCTION; CELL STIMULATION; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FASCIA; IMMUNOSTIMULATION; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; TISSUE REPAIR; UPREGULATION; WOUND; WOUND HEALING;

ANIMALS; BONE MARROW TRANSPLANTATION; EPIDERMAL GROWTH FACTOR; FASCIA; FIBROBLAST GROWTH FACTOR 7; HEPATOCYTE GROWTH FACTOR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 33750942497     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2006.07.037     Document Type: Article

References (32)

1. Steeper R.A. Critical review of the aetiology of diabetic neuropathic ulcers. J Wound Care 14 (2005) 101
2. Zimny S., and Pfohl M. Healing times and prediction of wound healing in neuropathic diabetic foot ulcers: A prospective study. Exp Clin Endocrinol Diabetes 113 (2005) 90
3. Gomez N.J. Wound care management in the end-stage renal disease population. Adv Ren Replace Ther 4 (1997) 390
4. Sieggreen M.Y., and Kline R.A. Recognizing and managing venous leg ulcers. Adv Skin Wound Care 17 (2004) 302
5. Ferguson M.K. The effect of antineoplastic agents on wound healing. Surg Gynecol Obstet 154 (1982) 421
6. Anstead G.M. Steroids, retinoids, and wound healing. Adv Wound Care 11 (1998) 277
7. Loots M.A., Lamme E.N., Zeegelaar J., Mekkes J.R., Bos J.D., and Middelkoop E. Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds. J Invest Dermatol 111 (1998) 850
8. Pierce G.F., Tarpley J.E., Allman R.M., et al. Tissue repair processes in healing chronic pressure ulcers treated with recombinant platelet-derived growth factor BB. Am J Pathol 145 (1994) 1399
9. Steed D.L. Modifying the wound healing response with exogenous growth factors. Clin Plast Surg 25 (1998) 397
10. Heng B.C., Liu H., and Cao T. Transplanted human embryonic stem cells as biological 'catalysts' for tissue repair and regeneration. Med Hypotheses 64 (2005) 1085
11. Robson M.C., Phillips L.G., Thomason A., Robson L.E., and Pierce G.F. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. Lancet 339 (1992) 23
12. Bennett S.P., Griffiths G.D., Schor A.M., Leese G.P., and Schor S.L. Growth factors in the treatment of diabetic foot ulcers. Br J Surg 90 (2003) 133
13. Pittenger M.F., Mackay A.M., Beck S.C., et al. Multilineage potential of adult human mesenchymal stem cells. Science 284 (1999) 143
14. Orlic D., Kajstura J., Chimenti S., et al. Bone marrow cells regenerate infarcted myocardium. Nature 410 (2001) 701
15. Prockop D.J. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276 (1997) 71
16. Yoon Y.S., Lee N., and Scadova H. Myocardial regeneration with bone-marrow-derived stem cells. Biol Cell 97 (2005) 253
17. Haynesworth S.E., Baber M.A., and Caplan A.I. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL-1 alpha. J Cellular Physiol 166 (1996) 585
18. Takai K., Hara J., Matsumoto K., et al. Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis. Blood 89 (1997) 1560
19. Chen X., Katakowski M., Li Y., et al. Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: growth factor production. J Neurosci Res 69 (2002) 687
20. Chopp M., and Li Y. Treatment of neural injury with marrow stromal cells. Lancet Neurol 1 (2002) 92
21. Orlic D., Kajstura J., Chimenti S., et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 98 (2001) 10344
22. Horowitz E.M., Prockop D.J., Fitzpatrick L.A., et al. Transplantability and therapeutic effects of bone marrow derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 5 (1999) 309
23. McFarlin K., Gao X., Liu Y., et al. Gautam. Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rats. Wound Rep Reg 14 (2006) 471
24. Jaiwal N., Haynesworth S.E., Caplan A.L., and Bruder S.P. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 64 (1997) 295
25. Ferrari G., Angelis G.C.-D., Coletta M., et al. Muscle regeneration by none marrow-derived myogenic progenitors. Science 279 (1998) 1528
26. Oswald J., Boxberger S., Jorgensen B., et al. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22 (2004) 377
27. Woodbury D., Schwarz E.J., Prockop D.J., and Black I.B. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61 (2000) 364
28. Badiavas E.V., Abedi M., Butmarc J., Falanga V., and Quesenberry P. Participation of bone marrow derived cells in cutaneous wound healing. J Cell Physiol 196 (2003) 245
29. Badiavas E.V., and Falanga V. Treatment of chronic wounds with bone marrow-derived cells. Arch Dermatol 139 (2003) 510
30. Yamaguchi Y., Kubo T., Murakami T., et al. Bone marrow cells differentiate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing. Br J Dermatol 152 (2005) 616
31. Singer A.J., and Clark R.A.F. Cutaneous wound healing. N Engl J Med 341 (1999) 738
32. Hackam D.J., and Ford H.R. Cellular, biochemical, and clinical aspects of wound healing. Surg Infect (Larchmt) 3 Suppl 1 (2002) S23