Subacute effects of carbofuran on enzyme functions in rat small intestine

Toxicology Mechanisms and Methods

Volumn 19, Issue 2, 2009, Pages 141-147

  Gera, Nidhi ^a   Kiran, Ravi ^a   Mahmood, Akhtar ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Brush border enzymes; Carbofuran (2,3 dihydro 2,2 dimethyl 7 benzofuranyl N methyl carbamate); Cellular enzymes; Intestinal morphology

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA GLUCOSIDASE; CARBAMIC ACID DERIVATIVE; CARBOFURAN; CYTOSOL AMINOPEPTIDASE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE 6 PHOSPHATASE; INTESTINE ENZYME; LACTASE; SUCRASE; TREHALASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRUSH BORDER; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; GROWTH RETARDATION; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANIMALS; BODY WEIGHT; CARBOFURAN; CHOLINESTERASE INHIBITORS; COMET ASSAY; INSECTICIDES; INTESTINE, SMALL; MALE; MICROVILLI; RATS; RATS, WISTAR; SUCRASE;

ANIMALIA; RATTUS;

EID: 61649117526     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510802355091     Document Type: Article

References (42)

1. Abou-Donia, M. B. 2003. Organophosphorous ester-induced chronic neurotoxicity. Arch. Environ. Health 58:484-497.
2. Ahdaya, S. M., and Guthrie, F. E. 1982. Stomach absorbtion of incubated insecticides in fasted mice. Toxicology 22:311-317.
3. Ahdaya, S. M., Monroe, R. J., and Guthrie, F. E. 1981. Absorption and distribution of incubated insecticides in fasted mice. Pestic. Biochem. Physiol. 16:38-46.
4. Azmi, A. S., Bhat, S. H., and Hadi, S. M. 2005. Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocyte: implication for anticancer properties. FEBS Lett. 579:3131-3135.
5. Bauer, V., Bezekova, M., Cilkova, D., and Benes, L. 1986. Carbamate induced rhythmic activity in the guinea-pig ileum. Drugs Exp. Clin. Res. 12:791-798.
6. Brasitus, T. A., Schachter, D., and Mamouneas, T. G. 1979. Functional interactions of lipids and protein in rat intestinal microvillus membrane. Biochemistry 18:4139-4144.
7. Bergmeyer, M. V. C. 1963. Methods of enzymatic analysis, Academic Press New York, pp. 736-741, 783-785, 788-790.
8. Chapalmadgu, S., and Chaudhry, G. R. 1992. Microbiological and biotechnological aspects of metabolism of Carbamates and organophosphates. Crit. Rev. Biotech. 12:357-389.
9. Dahlquist, A. 1964. Method for the assay of intestinal disaccharidase. Anal. Biochem. 7:18-25.
10. Dhawan, A., Mathur, N., and Seth, P. K. 2001. The effect of smoking and eating habits on DNA damage in Indian population as measured in the comet assay. Mutat. Res. 474:121-128.
11. Fahmg, M. A. H., Fukuto, T. R., and Myers, R. O. 1970. The selective toxicity of N- phosphorothionylcarbamate esters. J. Agric. Food Chem. 18:793-796.
12. FAO/WHO. 1985. 1983 Evaluation of some pesticide residues in food, Food and Agriculture Organization of the United Nations, Rome.
13. Fukuto, T. R. 1990. Mechanism of action of organophosphorous and carbamate insecticides. Environ. Health Perspect. 87:245-254.
14. Goda, T., Yasutake, H., Tanaka, T., and Takase, S. 1999. Lactase-phlorizin hydrolase and sucrase-isomaltase genes are expressed differently along the villus-crypt axis of rat jejunum. J. Nutr. 129:1107-1113.
15. Goldberg, J. A., and Ruttenberg, A. M. 1958. Colorimetric determination of leucine aminopeptidase in urine and serum of normal subjects and patient with cancer and other disease. Cancer 11:283-291.
16. Green, F., Edwards, Y., Hauri, H. P., Povey, S., Ho, M. W., Pinto, M., and Swallow, D. 1987. Isolation of cDNA probe for a human jejunal brush-border hydrolase, sucrase-isomaltase, and assignment of the gene locus to chromosome 3. Gene 57:101-110.
17. Gupta, R. C., and Goad, J. T. 2000. Role of high energy phosphate and their metabolite in protection of carbofuran-induced biochemical changes in diaphragm muscle by memantine. Arch. Toxicol. 74:13-20.
18. Gupta, R. C., and Kadel, W. L. 1989a. Concerted role of carboxylesterases in the potentiation of carbofuran toxicity by iso-OMPA pretreatment. J. Toxicol. Environ. Health 26:447-457.
19. Gupta, R. C., and Kadel, W. L. 1989b. Prevention and antagonism of acute carbofuran intoxication by memantine and atropine. J. Toxicol. Environ. Health 28:111-122.
20. Gupta, R. C., Goad, J. T., and Kadel, W. L. 1991a. Carbofuran-induced alteration (in vivo) in high energy phosphates, creatine kinase (CK) and CK isoenzymes. Arch. Toxicol. 65:304-310.
21. Gupta, R. C., Goad, J. T., and Kadel, W. L. 1991b. In vivo alterations in lactate dehydrogenase (LDH) and LDH isoenzymes patterns by acute carbofuran intoxication. Arch. Environ. Contam. Toxicol. 21:263-269.
22. Gupta, R. C., Goad, J. T., and Kadel, W. L. 1993. Protection and reversal by memantine and atropine of carbofuran- induced changes in biomarkers. Drug Dev. Res. 28:153-160.
23. Gupta, R. C., Goad, J. T., and Kadel, W. L. 1994. Cholinergic and noncholinergic changes in skeletal muscles by carbofuran and methylparathion. J. Toxicol. Environ. Health 43:291-304.
24. Henthorn, P. S., Raducha, M., Kadesch, T., Weiss, M. J., and Harris, H. 1988. Sequence and characterization of human intestinal alkalinephosphatase gene. J. Biol. Chem. 263:12011-12019.
25. Humason, G. L. 1979. Animal tissue technique, Freeman and company, San Francisco, CA.
26. Kamboj, A., Kiran, R., and Sandhir, R. 2006. Carbofuran-induced neurochemical and neurobehavioral alterations in rats: attenuation by N-acetylcysteine. Exp. Brain Res. 170:567-575.
27. Kessler, M., Acuto, O., Storelli, H., Murer, H., Muller, M., and Semenza, G. 1978. A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of D-glucose and choline transport systems. Biochim. Biophys. Acta 506:136-154.
28. Kuhr, R. J., and Dorough, H. W. 1976. Carbamate Insecticide: Chemistry, Biochemistry and Toxicology, CRC Press, Boca Raton.
29. Kruse, T. A., Bolund, L., Grzeschik, K. H., Ropers, H. H., Olsen, J., Sjostrom, H., and Noren, O. 1988. Assignment of the human aminopeptidase N (peptidase E) gene to chromosome 15q13-qter. FEBS Lett. 239:305-308.
30. Kumari, B., Madan, V. K., Khanna, Y. P., and Kathpal, T. S. 2002. Monitoring of seasonal vegetables for pesticide residues. Environ. Monit. Assess. 74:263-270.
31. Labana, S., Bansal, R. C., and Mahmood, A. 1997. Differential effects of lindane on intestinal functions in normal-fed and malnourished rats. Pestic. Biochem. Physiol. 57:192-197.
32. Labana, S., Bansal, R. C., and Mahmood, A. 2001. Effect of endosulfan on intestinal functions in protein-malnourished rats. Indian J. Exp. Biol. 39:1017-1021.
33. 4. Nature 227:680-685.
34. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with Folin phenol reagent. J. Biol. Chem. 193:265-275.
35. Mahmood, A., Agarwal, N., Dudeja, P. K., Sanay, S., Mahmood, R., and Subrahmanyam, D. 1981. Effect of a single dose of DDT on intestinal uptake of nutrients and brush border enzymes in protein-calorie-malnourished monkeys. Pestic. Biochem. Physiol. 15:143-148.
36. Mahmood, A., Mahmood, S., Desehruyer-Kecshimeti, K., and Alpers, D. H. 1993. Characterization of protein in rats and human intestinal surfactant like particles. Arch. Biochem. Biophys. 300:280-286.
37. Naftalin, L., Sexton, M., Whitaker, J. F., and Tracey, D. 1969. A routine procedure for estimating serum γ-glutamyl transpeptidase activity. Clin. Chim. Acta 26:293-296.
38. Pant, N., Prasad, A. K., Srivastava, S. C., Shankar, R., and Srivastava, S. P. 1995. Effect of oral administration of carbofuran on male reproductive system of rat. Human Exp. Toxicol. 16:267-272.
39. Reitman, S., and Frankel, S. 1957. A colorimeteric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28:56-63.
40. Sandhu, M., and Mahmood, A. 1990. Kinetic characteristic of soluble and brush border alkaline phosphatase and sucrase activities in developing rat intestine: effect of hormone. Indian J. Biochem. Biophys. 27:88-92.
41. Weiser, M. M. 1973. Intestinal epithelial cell surface membrane glycoprotein synthesis. J. Biol. Chem. 248:2536-2541.
42. Wojciechowski, J. P., Kaur, P., and Sabharwal, P. S. 1982. Induction of ouabain resistance in V-79 cells by four carbamate pesticides. Environ. Res. 29:148-153.