Posttreatment with aminoguanidine attenuates renal ischemia/reperfusion injury in rats

Renal Failure

Volumn 31, Issue 1, 2009, Pages 50-53

  Onem, Yalcin ^a   Ipcioglu, Osman Metin ^a   Haholu, Aptullah ^a   Sen, Huseyin ^a   Aydinoz, Secil ^a   Suleymanoglu, Selami ^a   Bilgi, Oguz ^a   Akyol, Ilker ^a  

^a GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

Author keywords

Acute renal failure; Aminoguanidine; Ischemia reperfusion; Nitric oxide

Indexed keywords

AMINOGUANIDINE; CREATININE; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; HISTOPATHOLOGY; KIDNEY DYSFUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE DAMAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SHAM PROCEDURE; SPRAGUE DAWLEY RAT; UREA BLOOD LEVEL;

ANIMALS; BLOOD UREA NITROGEN; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; GUANIDINES; KIDNEY FAILURE, ACUTE; MALE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 61649116674     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.1080/08860220802546313     Document Type: Article

References (16)

1. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med. 1996 May 30;334(22):1448-1460.
2. Chiao H, Kohda Y, McLeroy P, Craig L, Housini I, Star RA. Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats. J Clin Invest. 1997 Mar 15;99(6):1165-1172.
3. Solmazgul E, Uzun G, Cermik H, Atasoyu EM, Aydinoz S, Yildiz S. Hyperbaric oxygen therapy attenuates renal ischemia/reperfusion injury in rats. Urol Int. 2007;78(1): 82-85.
4. Kelly KJ, Williams WW Jr, Colvin RB, Meehan SM, Springer TA, Gutierrez-Ramos JC, Bonventre JV. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest. 1996 Feb 15;97(4):1056-1063.
5. Rabb H. Role of leukocytes and leukocyte adhesion molecules in renal ischemic-reperfusion injury. Front Biosci. 1996;1:e9-e14.
6. Chatterjee PK, Patel NS, Sivarajah A, Kvale EO, Dugo L, Cuzzocrea S, Brown PA, Stewart KN, Mota-Filipe H, Britti D, Yaqoob MM, Thiemermann C. GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int. 2003;63(3):853-865.
7. Giardino I, Fard AK, Hatchell DL, Brownlee M. Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes. 1998 Jul;47(7):1114-1120.
8. Polat A, Parlakpinar H, Tasdemir S, Colak C, Vardi N, Ucar M, Emre MH, Acet A. Protective role of aminoguanidine on gentamicin-induced acute renal failure in rats. Acta Histochem. 2006;108(5):365-371.
9. Yaylak F, Canbaz H, Caglikulekci M, Dirlik M, Tamer L, Ogetman Z, Polat Y, Kanik A, Aydin S. Liver tissue inducible nitric oxide synthase (iNOS) expression and lipid peroxidation in experimental hepatic ischemia reperfusion injury stimulated with lipopolysaccharide: The role of aminoguanidine. J Surg Res. 2008;148(2):214-223.
10. Barocelli E, Ballabeni V, Ghizzardi P, Cattaruzza F, Bertoni S, Lagrasta CA, Impicciatore M. The selective inhibition of inducible nitric oxide synthase prevents intestinal ischemia-reperfusion injury in mice. Nitric Oxide. 2006 May;14(3):212-218.
11. Cash D, Beech JS, Rayne RC, Bath PM, Meldrum BS, Williams SC. Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Res. 2001 Jun 29;905(1-2):91-103.
12. Sahna E, Parlakpinar H, Cihan OF, Turkoz Y, Acet A. Effects of aminoguanidine against renal ischaemia-reperfusion injury in rats. Cell Biochem Funct. 2006 Mar-Apr;24(2):137-141.
13. Zwemer CF, Shoemaker JL Jr, Hazard SW III, et al. Hyperoxic reperfusion exacerbates postischemic renal dysfunction. Surgery 2000;128:815-821.
14. Lien YH, Lai LW, Silva AL. Pathogenesis of renal ischemia/reperfusion injury: Lessons from knockout mice. Life Sci. 2003;74:543-552.
15. Walker LM, York JL, Imam SZ, et al. Oxidative stress and reactive nitrogen species generation during renal ischemia Toxicol Sci. 2001;63:143-148.
16. Walker LM, Walker PD, Imam SZ, Ali SF, Mayeux PR. Evidence for peroxynitrite formation in renal ischemia-reperfusion injury: Studies with the inducible nitric oxide synthase inhibitor L-N(6)-( 1-iminoethyl) lysine. J Pharmacol Exp Ther. 2000 Oct;295(1):417-422.