Origin and dispersal of atypical aldehyde dehydrogenase ALDH2*487Lys

Gene

Volumn 435, Issue 1-2, 2009, Pages 96-103

  Luo, Huai Rong ^a   Wu, Gui Sheng ^a,b   Pakstis, Andrew J ^c   Tong, Li ^d   Oota, Hiroki ^c   Kidd, Kenneth K ^c   Zhang, Ya Ping ^a,b  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b YUNNAN UNIVERSITY   (China)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

ALDH2; ALDH2*487Lys; East Asian; Haplotype; Origin

Indexed keywords

ALDEHYDE DEHYDROGENASE; LYSINE;

ALDH2 GENE; ARTICLE; GENE; GENE FREQUENCY; GENE LOCATION; GENE LOCUS; GENETIC CODE; HAPLOTYPE; HUMAN; POPULATION GENETIC PARAMETERS; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ACETALDEHYDE; ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; EVOLUTION, MOLECULAR; FLUSHING; GENETICS, POPULATION; GENOTYPE; HAPLOTYPES; HUMANS; LYSINE; MICROSATELLITE REPEATS; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 61649114406     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2008.12.021     Document Type: Article

References (55)

1. Bhaskar L.V., Thangaraj K., Osier M., Reddy A.G., Rao A.P., Singh L., and Rao V.R. Single nucleotide polymorphisms of the ALDH2 gene in six Indian populations. Ann. Hum. Biol. 34 (2007) 607-619
2. Braun T., Grzeschik K.H., Bober E., Singh S., Agarwal D.P., and Goedde H.W. The structural gene for the mitochondrial aldehyde dehydrogenase maps to human chromosome 12. Hum. Genet. 73 (1986) 365-367
3. Brown B.T., Woerner A., and Wilder J.A. Ascertainment bias and the pattern of nucleotide diversity at the human ALDH2 locus in a Japanese population. J. Mol. Evol. 64 (2007) 375-385
4. Cao X., and Wu D. Compare of distributions of gene polymorphisms about alcohol metabolizing-related enzymes in five Chinese nationalities. Wei Sheng Yan Jiu 31 (2002) 156-159
5. Chen C.C., Lu R.B., Chen Y.C., Wang M.F., Chang Y.C., Li T.K., and Yin S.J. Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. Am. J. Hum. Genet. 65 (1999) 795-807
6. Chen Y.C., Lu R.B., Peng G.S., Wang M.F., Wang H.K., Ko H.C., Chang Y.C., Lu J.J., Li T.K., and Yin S.J. Alcohol metabolism and cardiovascular response in an alcoholic patient homozygous for the ALDH2*2 variant gene allele. Alcohol. Clin. Exp. Res. 23 (1999) 1853-1860
7. Chen C.H., Budas G.R., Churchill E.N., Disatnik M.H., Hurley T.D., and Mochly-Rosen D. Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science 321 (2008) 1493
8. Crabb D.W., Edenberg H.J., Bosron W.F., and Li T.K. Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant. J. Clin. Invest. 83 (1989) 314-316
9. Crabb D.W., Matsumoto M., Chang D., and You M. Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc. Nutr. Soc. 63 (2004) 49-63
10. Du R., and Yip V. Ethnic Groups in China (1993), Science Press, Beijing
11. Goedde H.W., Agarwal D.P., Fritze G., Meier-Tackmann D., Singh S., Beckmann G., Bhatia K., Chen L.Z., Fang B., Lisker R., et al. Distribution of ADH2 and ALDH2 genotypes in different populations. Hum. Genet. 88 (1992) 344-346
12. Goedde H.W., Agarwal D.P., Harada S., Rothhammer F., Whittaker J.O., and Lisker R. Aldehyde dehydrogenase polymorphism in North American, South American, and Mexican Indian populations. Am. J. Hum. Genet. 38 (1986) 395-399
13. Goldman D., and Enoch M.A. Genetic epidemiology of ethanol metabolic enzymes: a role for selection. World Rev. Nutr. Diet. 63 (1990) 143-160
14. Greenfield N.J., and Pietruszko R. Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes. Biochim. Biophys. Acta 483 (1977) 35-45
15. Hammer M.F., Karafet T.M., Park H., Omoto K., Harihara S., Stoneking M., and Horai S. Dual origins of the Japanese: common ground for hunter-gatherer and farmer Y chromosomes. J. Hum. Genet. 51 (2006) 47-58
16. Harada S., Misawa S., Agarwal D.P., and Goedde H.W. Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication. Am. J. Hum. Genet. 32 (1980) 8-15
17. Hawley M.E., and Kidd K.K. HAPLO: a program using the EM algorithm to estimate the frequencies of multi-site haplotypes. J. Hered. 86 (1995) 409-411
18. Hsu L.C., Tani K., Fujiyoshi T., Kurachi K., and Yoshida A. Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2. Proc. Natl. Acad. Sci. U. S. A. 82 (1985) 3771-3775
19. Hsu L.C., Yoshida A., and Mohandas T. Chromosomal assignment of the genes for human aldehyde dehydrogenase-1 and aldehyde dehydrogenase-2. Am. J. Hum. Genet. 38 (1986) 641-648
20. Ikawa M., Impraim C.C., Wang G., and Yoshida A. Isolation and characterization of aldehyde dehydrogenase isozymes from usual and atypical human livers. J. Biol. Chem. 258 (1983) 6282-6287
21. Ikuta T., Szeto S., and Yoshida A. Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 634-638
22. Impraim C., Wang G., and Yoshida A. Structural mutation in a major human aldehyde dehydrogenase gene results in loss of enzyme activity. Am. J. Hum. Genet. 34 (1982) 837-841
23. Jin H.J., Kwak K.D., Hammer M.F., Nakahori Y., Shinka T., Lee J.W., Jin F., Jia X., Tyler-Smith C., and Kim W. Y-chromosomal DNA haplogroups and their implications for the dual origins of the Koreans. Hum. Genet. 114 (2003) 27-35
24. Kivisild T., Tolk H.V., Parik J., Wang Y., Papiha S.S., Bandelt H.J., and Villems R. The emerging limbs and twigs of the East Asian mtDNA tree. Mol. Biol. Evol. 19 (2002) 1737-1751
25. Kong Q.P., Yao Y.G., Liu M., Shen S.P., Chen C., Zhu C.L., Palanichamy M.G., and Zhang Y.P. Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China. Hum. Genet. 113 (2003) 391-405
26. Li S.L., Yamamoto T., Yoshimoto T., Uchihi R., Mizutani M., Kurimoto Y., Tokunaga K., Jin F., Katsumata Y., and Saitou N. Phylogenetic relationship of the populations within and around Japan using 105 short tandem repeat polymorphic loci. Hum. Genet. 118 (2006) 695-707
27. Lin Y.P., and Cheng T.J. Why can't Chinese Han drink alcohol? Hepatitis B virus infection and the evolution of acetaldehyde dehydrogenase deficiency. Med. Hypotheses 59 (2002) 204-207
28. Luczak S.E., Glatt S.J., and Wall T.L. Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians. Psychol. Bull. 132 (2006) 607-621
29. Luo H.R., Israel Y., Tu G.C., Eriksson C.J., and Zhang Y.P. Genetic polymorphism of aldehyde dehydrogenase 2 (ALDH2) in a Chinese population: gender, age, culture, and genotypes of ALDH2. Biochem. Genet. 43 (2005) 223-227
30. Luu S.U., Wang M.F., Lin D.L., Kao M.H., Chen M.L., Chiang C.H., Pai L., and Yin S.J. Ethanol and acetaldehyde metabolism in Chinese with different aldehyde dehydrogenase-2 genotypes. Proc. Natl. Sci. Counc. Repub. China B 19 (1995) 129-136
31. Ma Y. China's Minority Nationalities (1994), Foreign Languages Press, Beijing
32. Maezawa Y., Yamauchi M., Toda G., Suzuki H., and Sakurai S. Alcohol-metabolizing enzyme polymorphisms and alcoholism in Japan. Alcohol. Clin. Exp. Res. 19 (1995) 951-954
33. Murata M., Tagawa M., Watanabe S., Kimura H., Takeshita T., and Morimoto K. Genotype difference of aldehyde dehydrogenase 2 gene in alcohol drinkers influences the incidence of Japanese colorectal cancer patients. Jpn. J. Cancer Res. 90 (1999) 711-719
34. Oota H., Pakstis A.J., Bonne-Tamir B., Goldman D., Grigorenko E., Kajuna S.L., Karoma N.J., Kungulilo S., Lu R.B., Odunsi K., Okonofua F., Zhukova O.V., Kidd J.R., and Kidd K.K. The evolution and population genetics of the ALDH2 locus: random genetic drift, selection, and low levels of recombination. Ann. Hum. Genet. 68 (2004) 93-109
35. Peterson R.J., Goldman D., and Long J.C. Nucleotide sequence diversity in non-coding regions of ALDH2 as revealed by restriction enzyme and SSCP analysis. Hum. Genet. 104 (1999) 177-187
36. Peterson R.J., Goldman D., and Long J.C. Effects of worldwide population subdivision on ALDH2 linkage disequilibrium 9 (1999), Genome Res. 844-852
37. Schwitters S.Y., Johnson R.C., Johnson S.B., and Ahern F.M. Familial resemblances in flushing following alcohol use. Behav. Genet. 12 (1982) 349-352
38. Shi H., Dong Y.L., Wen B., Xiao C.J., Underhill P.A., Shen P.D., Chakraborty R., Jin L., and Su B. Y-chromosome evidence of southern origin of the East Asian-specific haplogroup O3-M122. Am. J. Hum. Genet. 77 (2005) 408-419
39. Singh S., Fritze G., Fang B.L., Harada S., Paik Y.K., Eckey R., Agarwal D.P., and Goedde H.W. Inheritance of mitochondrial aldehyde dehydrogenase: genotyping in Chinese, Japanese and South Korean families reveals dominance of the mutant allele. Hum. Genet. 83 (1989) 119-121
40. Stamatoyannopoulos G., Chen S.H., and Fukui M. Liver alcohol dehydrogenase in Japanese: high population frequency of atypical form and its possible role in alcohol sensitivity. Am. J. Hum. Genet. 27 (1975) 789-796
41. Takada A., Tsutsumi M., and Kobayashi Y. Genotypes of ALDH2 related to liver and pulmonary diseases and other genetic factors related to alcoholic liver disease. Alcohol Alcohol 29 (1994) 719-727
42. Takeshita T., Morimoto K., Mao X., Hashimoto T., and Furuyama J. Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population. Hum. Genet. 94 (1994) 217-223
43. Tu G.C., and Israel Y. Alcohol consumption by orientals in North America is predicted largely by a single gene. Behav. Genet. 25 (1995) 59-65
44. Wall T.L., Horn S.M., Johnson M.L., Smith T.L., and Carr L.G. Hangover symptoms in Asian Americans with variations in the aldehyde dehydrogenase (ALDH2) gene. J. Stud. Alcohol 61 (2000) 13-17
45. Wolff P.H. Ethnic differences in alcohol sensitivity. Science 175 (1972) 449-450
46. Wang W.G., and Li X.W. The Development and Evolving History of Pai-Yuei Tribe-From Yuei, Liao to Dong and Other Tribes (2007), The Ethnic Publishing House, Beijing
47. Yao Y.G., Kong Q.P., Wang C.Y., Zhu C.L., and Zhang Y.P. Different matrilineal contributions to genetic structure of ethnic groups in the silk road region in china. Mol. Biol. Evol. 21 (2004) 2265-2280
48. Yokoyama A., Muramatsu T., Ohmori T., Higuchi S., Hayashida M., and Ishii H. Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males. Cancer Epidemiol. Biomarkers Prev. 5 (1996) 99-102
49. Yokoyama A., Muramatsu T., Ohmori T., Makuuchi H., Higuchi S., Matsushita S., Yoshino K., Maruyama K., Nakano M., and Ishii H. Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase-2 genotype of Japanese alcoholics. Cancer 77 (1996) 1986-1990
50. Yokoyama A., Muramatsu T., Ohmori T., Yokoyama T., Okuyama K., Takahashi H., Hasegawa Y., Higuchi S., Maruyama K., Shirakura K., and Ishii H. Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis 19 (1998) 1383-1387
51. Yokoyama A., Ohmori T., Muramatsu T., Higuchi S., Yokoyama T., Matsushita S., Matsumoto M., Maruyama K., Hayashida M., and Ishii H. Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 genotype. Int. J. Cancer 68 (1996) 313-316
52. Yokoyama M., Yokoyama A., Yokoyama T., Funazu K., Hamana G., Kondo S., Yamashita T., and Nakamura H. Hangover susceptibility in relation to aldehyde dehydrogenase-2 genotype, alcohol flushing, and mean corpuscular volume in Japanese workers. Alcohol. Clin. Exp. Res. 29 (2005) 1165-1171
53. Yoshida A., Huang I.Y., and Ikawa M. Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals. Proc. Natl. Acad. Sci. U. S. A. 81 (1984) 258-261
54. Yoshida A., Wang G., and Dave V. Determination of genotypes of human aldehyde dehydrogenase ALDH2 locus. Am. J. Hum. Genet. 35 (1983) 1107-1116
55. You Z. History of Yunnan Nationalities (1994), Yunnan University Press, Kunming