-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., and Mello C.C. Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans. Nature 391 6669 (1998) 806-811
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
0037733977
-
Antisense technologies. Improvement through novel chemical modifications
-
Kurreck J. Antisense technologies. Improvement through novel chemical modifications. Eur. J. Biochem. 270 8 (2003) 1628-1644
-
(2003)
Eur. J. Biochem.
, vol.270
, Issue.8
, pp. 1628-1644
-
-
Kurreck, J.1
-
3
-
-
1942499451
-
Improving the efficiency of RNA interference in mammals
-
Mittal V. Improving the efficiency of RNA interference in mammals. Nat. Rev., Genet. 5 5 (2004) 355-365
-
(2004)
Nat. Rev., Genet.
, vol.5
, Issue.5
, pp. 355-365
-
-
Mittal, V.1
-
4
-
-
34548532823
-
Targeted delivery systems of small interfering RNA by systemic administration
-
Kawakami S., and Hashida M. Targeted delivery systems of small interfering RNA by systemic administration. Drug Metab. Pharmacokinet 22 3 (2007) 142-151
-
(2007)
Drug Metab. Pharmacokinet
, vol.22
, Issue.3
, pp. 142-151
-
-
Kawakami, S.1
Hashida, M.2
-
5
-
-
0033968956
-
Biophysical and lipofection studies of dotap analogs
-
Regelin A.E., Fankhaenel S., Gurtesch L., Prinz C., von Kiedrowski G., and Massing U. Biophysical and lipofection studies of dotap analogs. Biochim. Biophys. Acta 1464 1 (2000) 151-164
-
(2000)
Biochim. Biophys. Acta
, vol.1464
, Issue.1
, pp. 151-164
-
-
Regelin, A.E.1
Fankhaenel, S.2
Gurtesch, L.3
Prinz, C.4
von Kiedrowski, G.5
Massing, U.6
-
6
-
-
33751099034
-
RNAi therapeutics: A potential new class of pharmaceutical drugs
-
Bumcrot D., Manoharan M., Koteliansky V., and Sah D.W. RNAi therapeutics: A potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2 12 (2006) 711-719
-
(2006)
Nat. Chem. Biol.
, vol.2
, Issue.12
, pp. 711-719
-
-
Bumcrot, D.1
Manoharan, M.2
Koteliansky, V.3
Sah, D.W.4
-
7
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
Zimmermann T.S., Lee A.C., Akinc A., Bramlage B., Bumcrot D., Fedoruk M.N., Harborth J., Heyes J.A., Jeffs L.B., John M., Judge A.D., Lam K., McClintock K., Nechev L.V., Palmer L.R., Racie T., Rohl I., Seiffert S., Shanmugam S., Sood V., Soutschek J., Toudjarska I., Wheat A.J., Yaworski E., Zedalis W., Koteliansky V., Manoharan M., Vornlocher H.P., and MacLachlan I. RNAi-mediated gene silencing in non-human primates. Nature 441 7089 (2006) 111-114
-
(2006)
Nature
, vol.441
, Issue.7089
, pp. 111-114
-
-
Zimmermann, T.S.1
Lee, A.C.2
Akinc, A.3
Bramlage, B.4
Bumcrot, D.5
Fedoruk, M.N.6
Harborth, J.7
Heyes, J.A.8
Jeffs, L.B.9
John, M.10
Judge, A.D.11
Lam, K.12
McClintock, K.13
Nechev, L.V.14
Palmer, L.R.15
Racie, T.16
Rohl, I.17
Seiffert, S.18
Shanmugam, S.19
Sood, V.20
Soutschek, J.21
Toudjarska, I.22
Wheat, A.J.23
Yaworski, E.24
Zedalis, W.25
Koteliansky, V.26
Manoharan, M.27
Vornlocher, H.P.28
MacLachlan, I.29
more..
-
8
-
-
40949126550
-
Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth
-
Merritt W.M., Lin Y.G., Spannuth W.A., Fletcher M.S., Kamat A.A., Han L.Y., Landen C.N., Jennings N., De Geest K., Langley R.R., Villares G., Sanguino A., Lutgendorf S.K., Lopez-Berestein G., Bar-Eli M.M., and Sood A.K. Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth. J. Natl. Cancer Inst. 100 5 (2008) 359-372
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, Issue.5
, pp. 359-372
-
-
Merritt, W.M.1
Lin, Y.G.2
Spannuth, W.A.3
Fletcher, M.S.4
Kamat, A.A.5
Han, L.Y.6
Landen, C.N.7
Jennings, N.8
De Geest, K.9
Langley, R.R.10
Villares, G.11
Sanguino, A.12
Lutgendorf, S.K.13
Lopez-Berestein, G.14
Bar-Eli, M.M.15
Sood, A.K.16
-
9
-
-
33748364149
-
Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy
-
Halder J., Kamat A.A., Landen Jr. C.N., Han L.Y., Lutgendorf S.K., Lin Y.G., Merritt W.M., Jennings N.B., Chavez-Reyes A., Coleman R.L., Gershenson D.M., Schmandt R., Cole S.W., Lopez-Berestein G., and Sood A.K. Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy. Clin. Cancer Res. 12 16 (2006) 4916-4924
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.16
, pp. 4916-4924
-
-
Halder, J.1
Kamat, A.A.2
Landen Jr., C.N.3
Han, L.Y.4
Lutgendorf, S.K.5
Lin, Y.G.6
Merritt, W.M.7
Jennings, N.B.8
Chavez-Reyes, A.9
Coleman, R.L.10
Gershenson, D.M.11
Schmandt, R.12
Cole, S.W.13
Lopez-Berestein, G.14
Sood, A.K.15
-
10
-
-
23044506285
-
Therapeutic epha2 gene targeting in vivo using neutral liposomal small interfering RNA delivery
-
Landen Jr. C.N., Chavez-Reyes A., Bucana C., Schmandt R., Deavers M.T., Lopez-Berestein G., and Sood A.K. Therapeutic epha2 gene targeting in vivo using neutral liposomal small interfering RNA delivery. Cancer Res. 65 15 (2005) 6910-6918
-
(2005)
Cancer Res.
, vol.65
, Issue.15
, pp. 6910-6918
-
-
Landen Jr., C.N.1
Chavez-Reyes, A.2
Bucana, C.3
Schmandt, R.4
Deavers, M.T.5
Lopez-Berestein, G.6
Sood, A.K.7
-
11
-
-
85012373035
-
Diffusion of univalent ions across the lamellae of swollen phospholipids
-
Bangham A.D., Standish M.M., and Watkins J.C. Diffusion of univalent ions across the lamellae of swollen phospholipids. J. Mol. Biol. 13 1 (1965) 238-252
-
(1965)
J. Mol. Biol.
, vol.13
, Issue.1
, pp. 238-252
-
-
Bangham, A.D.1
Standish, M.M.2
Watkins, J.C.3
-
12
-
-
0033867851
-
Liposomal formulations of anticancer drugs: selectivity and effectiveness
-
Massing U., and Fuxius S. Liposomal formulations of anticancer drugs: selectivity and effectiveness. Drug Resist. Updat. 3 3 (2000) 171-177
-
(2000)
Drug Resist. Updat.
, vol.3
, Issue.3
, pp. 171-177
-
-
Massing, U.1
Fuxius, S.2
-
13
-
-
0036232598
-
Change in pharmacokinetic and pharmacodynamic behavior of gemcitabine in human tumor xenografts upon entrapment in vesicular phospholipid gels
-
Moog R., Burger A.M., Brandl M., Schuler J., Schubert R., Unger C., Fiebig H.H., and Massing U. Change in pharmacokinetic and pharmacodynamic behavior of gemcitabine in human tumor xenografts upon entrapment in vesicular phospholipid gels. Cancer Chemother. Pharmacol. 49 5 (2002) 356-366
-
(2002)
Cancer Chemother. Pharmacol.
, vol.49
, Issue.5
, pp. 356-366
-
-
Moog, R.1
Burger, A.M.2
Brandl, M.3
Schuler, J.4
Schubert, R.5
Unger, C.6
Fiebig, H.H.7
Massing, U.8
-
14
-
-
0141786835
-
Liposomal anthracyclines in metastatic breast cancer: clinical update
-
Rivera E. Liposomal anthracyclines in metastatic breast cancer: clinical update. Oncologist 8 Suppl 2 (2003) 3-9
-
(2003)
Oncologist
, vol.8
, Issue.SUPPL. 2
, pp. 3-9
-
-
Rivera, E.1
-
15
-
-
0026718957
-
Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors
-
Forssen E.A., Coulter D.M., and Proffitt R.T. Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors. Cancer Res. 52 12 (1992) 3255-3261
-
(1992)
Cancer Res.
, vol.52
, Issue.12
, pp. 3255-3261
-
-
Forssen, E.A.1
Coulter, D.M.2
Proffitt, R.T.3
-
16
-
-
0031044468
-
Cancer therapy with liposomal formulations of anticancer drugs
-
Massing U. Cancer therapy with liposomal formulations of anticancer drugs. Int. J. Clin. Pharmacol. Ther. 35 2 (1997) 87-90
-
(1997)
Int. J. Clin. Pharmacol. Ther.
, vol.35
, Issue.2
, pp. 87-90
-
-
Massing, U.1
-
17
-
-
0027269555
-
In-vitro stability and cytostatic activity of liposomal formulations of 5-fluoro-2'-deoxyuridine and its diacylated derivatives
-
van Borssum Waalkes M., van Galen M., Morselt H., Sternberg B., and Scherphof G.L. In-vitro stability and cytostatic activity of liposomal formulations of 5-fluoro-2'-deoxyuridine and its diacylated derivatives. Biochim. Biophys. Acta 1148 1 (1993) 161-172
-
(1993)
Biochim. Biophys. Acta
, vol.1148
, Issue.1
, pp. 161-172
-
-
van Borssum Waalkes, M.1
van Galen, M.2
Morselt, H.3
Sternberg, B.4
Scherphof, G.L.5
-
18
-
-
0842279809
-
Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors
-
Gabizon A., and Papahadjopoulos D. Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors. Proc. Natl. Acad. Sci. U. S. A. 85 18 (1988) 6949-6953
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, Issue.18
, pp. 6949-6953
-
-
Gabizon, A.1
Papahadjopoulos, D.2
-
19
-
-
0023219734
-
Transport of molecules in the tumor interstitium: a review
-
Jain R.K. Transport of molecules in the tumor interstitium: a review. Cancer Res. 47 12 (1987) 3039-3051
-
(1987)
Cancer Res.
, vol.47
, Issue.12
, pp. 3039-3051
-
-
Jain, R.K.1
-
20
-
-
0029150245
-
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size
-
Yuan F., Dellian M., Fukumura D., Leunig M., Berk D.A., Torchilin V.P., and Jain R.K. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 55 17 (1995) 3752-3756
-
(1995)
Cancer Res.
, vol.55
, Issue.17
, pp. 3752-3756
-
-
Yuan, F.1
Dellian, M.2
Fukumura, D.3
Leunig, M.4
Berk, D.A.5
Torchilin, V.P.6
Jain, R.K.7
-
21
-
-
0026694788
-
Passive tumor targeting of soluble macromolecules and drug conjugates
-
Seymour L.W. Passive tumor targeting of soluble macromolecules and drug conjugates. Crit. Rev. Ther. Drug Carr. Syst. 9 2 (1992) 135-187
-
(1992)
Crit. Rev. Ther. Drug Carr. Syst.
, vol.9
, Issue.2
, pp. 135-187
-
-
Seymour, L.W.1
-
22
-
-
0028326452
-
Liposome-complement interactions in rat serum: implications for liposome survival studies
-
Devine D.V., Wong K., Serrano K., Chonn A., and Cullis P.R. Liposome-complement interactions in rat serum: implications for liposome survival studies. Biochim. Biophys. Acta 1191 1 (1994) 43-51
-
(1994)
Biochim. Biophys. Acta
, vol.1191
, Issue.1
, pp. 43-51
-
-
Devine, D.V.1
Wong, K.2
Serrano, K.3
Chonn, A.4
Cullis, P.R.5
-
23
-
-
0026541171
-
Serum opsonins and liposomes: their interaction and opsonophagocytosis
-
Patel H.M. Serum opsonins and liposomes: their interaction and opsonophagocytosis. Crit. Rev. Ther. Drug Carr. Syst. 9 1 (1992) 39-90
-
(1992)
Crit. Rev. Ther. Drug Carr. Syst.
, vol.9
, Issue.1
, pp. 39-90
-
-
Patel, H.M.1
-
24
-
-
0015795402
-
Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol
-
Papahadjopoulos D., Jacobson K., Nir S., and Isac T. Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol. Biochim. Biophys. Acta 311 3 (1973) 330-348
-
(1973)
Biochim. Biophys. Acta
, vol.311
, Issue.3
, pp. 330-348
-
-
Papahadjopoulos, D.1
Jacobson, K.2
Nir, S.3
Isac, T.4
-
25
-
-
0029095751
-
New synthetic amphiphilic polymers for steric protection of liposomes in vivo
-
Torchilin V.P., Trubetskoy V.S., Whiteman K.R., Caliceti P., Ferruti P., and Veronese F.M. New synthetic amphiphilic polymers for steric protection of liposomes in vivo. J. Pharm. Sci. 84 9 (1995) 1049-1053
-
(1995)
J. Pharm. Sci.
, vol.84
, Issue.9
, pp. 1049-1053
-
-
Torchilin, V.P.1
Trubetskoy, V.S.2
Whiteman, K.R.3
Caliceti, P.4
Ferruti, P.5
Veronese, F.M.6
-
26
-
-
0026352832
-
Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy
-
Papahadjopoulos D., Allen T.M., Gabizon A., Mayhew E., Matthay K., Huang S.K., Lee K.D., Woodle M.C., Lasic D.D., Redemann C., et al. Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci. U. S. A. 88 24 (1991) 11460-11464
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, Issue.24
, pp. 11460-11464
-
-
Papahadjopoulos, D.1
Allen, T.M.2
Gabizon, A.3
Mayhew, E.4
Matthay, K.5
Huang, S.K.6
Lee, K.D.7
Woodle, M.C.8
Lasic, D.D.9
Redemann, C.10
-
27
-
-
0026552096
-
Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes
-
Woodle M.C., Matthay K.K., Newman M.S., Hidayat J.E., Collins L.R., Redemann C., Martin F.J., and Papahadjopoulos D. Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes. Biochim. Biophys. Acta 1105 2 (1992) 193-200
-
(1992)
Biochim. Biophys. Acta
, vol.1105
, Issue.2
, pp. 193-200
-
-
Woodle, M.C.1
Matthay, K.K.2
Newman, M.S.3
Hidayat, J.E.4
Collins, L.R.5
Redemann, C.6
Martin, F.J.7
Papahadjopoulos, D.8
-
28
-
-
0025731906
-
Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo
-
Allen T.M., Hansen C., Martin F., Redemann C., and Yau-Young A. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim. Biophys. Acta 1066 1 (1991) 29-36
-
(1991)
Biochim. Biophys. Acta
, vol.1066
, Issue.1
, pp. 29-36
-
-
Allen, T.M.1
Hansen, C.2
Martin, F.3
Redemann, C.4
Yau-Young, A.5
-
29
-
-
0035979414
-
Filter extrusion of liposomes using different devices: comparison of liposome size, encapsulation efficiency, and process characteristics
-
Berger N., Sachse A., Bender J., Schubert R., and Brandl M. Filter extrusion of liposomes using different devices: comparison of liposome size, encapsulation efficiency, and process characteristics. Int. J. Pharm. 223 1-2 (2001) 55-68
-
(2001)
Int. J. Pharm.
, vol.223
, Issue.1-2
, pp. 55-68
-
-
Berger, N.1
Sachse, A.2
Bender, J.3
Schubert, R.4
Brandl, M.5
-
30
-
-
34247366412
-
Vesicular phospholipid gels: a technology platform
-
Brandl M. Vesicular phospholipid gels: a technology platform. J. Liposome Res. 17 1 (2007) 15-26
-
(2007)
J. Liposome Res.
, vol.17
, Issue.1
, pp. 15-26
-
-
Brandl, M.1
-
31
-
-
0017678750
-
[differentiated approach to the evaluation of the asthmatic syndrome in acute pneumonias in young children]
-
Safronova O.N. [differentiated approach to the evaluation of the asthmatic syndrome in acute pneumonias in young children]. Pediatr. Akus. Ginekol. 6 (1977) 18-20
-
(1977)
Pediatr. Akus. Ginekol.
, vol.6
, pp. 18-20
-
-
Safronova, O.N.1
-
32
-
-
0018795181
-
Formation of unilamellar lipid vesicles of controllable dimensions by detergent dialysis
-
Rhoden V., and Goldin S.M. Formation of unilamellar lipid vesicles of controllable dimensions by detergent dialysis. Biochemistry 18 19 (1979) 4173-4176
-
(1979)
Biochemistry
, vol.18
, Issue.19
, pp. 4173-4176
-
-
Rhoden, V.1
Goldin, S.M.2
-
33
-
-
31544446865
-
Liposomes: an overview of manufacturing techniques
-
Mozafari M.R. Liposomes: an overview of manufacturing techniques. Cell. Mol. Biol. Lett. 10 4 (2005) 711-719
-
(2005)
Cell. Mol. Biol. Lett.
, vol.10
, Issue.4
, pp. 711-719
-
-
Mozafari, M.R.1
-
34
-
-
36649020910
-
Dual asymmetric centrifugation (dac)-a new technique for liposome preparation
-
Massing U., Cicko S., and Ziroli V. Dual asymmetric centrifugation (dac)-a new technique for liposome preparation. J. Control. Release 125 1 (2008) 16-24
-
(2008)
J. Control. Release
, vol.125
, Issue.1
, pp. 16-24
-
-
Massing, U.1
Cicko, S.2
Ziroli, V.3
-
35
-
-
35548965556
-
Surveillance of sirna integrity by fret imaging
-
Jarve A., Muller J., Kim I.H., Rohr K., MacLean C., Fricker G., Massing U., Eberle F., Dalpke A., Fischer R., Trendelenburg M.F., and Helm M. Surveillance of sirna integrity by fret imaging. Nucleic Acids Res. 35 18 (2007) e124
-
(2007)
Nucleic Acids Res.
, vol.35
, Issue.18
-
-
Jarve, A.1
Muller, J.2
Kim, I.H.3
Rohr, K.4
MacLean, C.5
Fricker, G.6
Massing, U.7
Eberle, F.8
Dalpke, A.9
Fischer, R.10
Trendelenburg, M.F.11
Helm, M.12
-
36
-
-
37249047522
-
A new liposomal formulation of gemcitabine is active in an orthotopic mouse model of pancreatic cancer accessible to bioluminescence imaging
-
Bornmann C., Graeser R., Esser N., Ziroli V., Jantscheff P., Keck T., Unger C., Hopt U.T., Adam U., Schaechtele C., Massing U., and von Dobschuetz E. A new liposomal formulation of gemcitabine is active in an orthotopic mouse model of pancreatic cancer accessible to bioluminescence imaging. Cancer Chemother. Pharmacol. 61 3 (2008) 395-405
-
(2008)
Cancer Chemother. Pharmacol.
, vol.61
, Issue.3
, pp. 395-405
-
-
Bornmann, C.1
Graeser, R.2
Esser, N.3
Ziroli, V.4
Jantscheff, P.5
Keck, T.6
Unger, C.7
Hopt, U.T.8
Adam, U.9
Schaechtele, C.10
Massing, U.11
von Dobschuetz, E.12
-
37
-
-
0014196992
-
Phospholipid model membranes. Ii. Permeability properties of hydrated liquid crystals
-
Papahadjopoulos D., and Watkins J.C. Phospholipid model membranes. Ii. Permeability properties of hydrated liquid crystals. Biochim. Biophys. Acta 135 4 (1967) 639-652
-
(1967)
Biochim. Biophys. Acta
, vol.135
, Issue.4
, pp. 639-652
-
-
Papahadjopoulos, D.1
Watkins, J.C.2
|