Accelerated 32P-HPLC for bulky DNA adducts

Mutagenesis

Volumn 24, Issue 2, 2009, Pages 183-189

  Nagy, Eszter ^a,b   Cornelius, Michael G ^a   Möller, Lennart ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PYRICARBATE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; RADIATION DETECTION;

BENZ(A)ANTHRACENES; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA ADDUCTS; HUMANS; PHOSPHORUS RADIOISOTOPES; REFERENCE STANDARDS;

EID: 61649100491     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gen070     Document Type: Article

References (27)

1. Beland, F. A. and Marques, M. M. (1994) DNA adducts of nitropolycyclic aromatic hydrocarbons. IARC Sci. Publ., 125, 229-244.
2. Dipple, A. (1995) DNA adducts of chemical carcinogens. Carcinogenesis, 16, 437-441.
3. Farmer, P. B., Sepai, O., Lawrence, R. et al. (1996) Biomonitoring human exposure to environmental carcinogenic chemicals. Mutagenesis, 11, 363-381.
4. Garner, R. C. (1998) The role of DNA adducts in chemical carcinogenesis. Mutat. Res., 402, 67-75.
5. Kadlubar, F. F. (1994) DNA adducts of carcinogenic aromatic amines. IARC Sci. Publ., 125, 199-216.
6. Poirier, M. C. (1997) DNA adducts as exposure biomarkers and indicators of cancer risk. Environ. Health Perspect., 105, 907-912.
7. Phillips, D. H. (2005) DNA adducts as markers of exposure and risk. Mutat. Res., 577, 284-292.
8. 32P-postlabeling analysis of aromatic carcinogen: DNA adducts. Cancer Res., 45, 5656-5662.
9. 32P-postlabeled DNA-aromatic carcinogen adducts. Anal. Biochem., 174, 381-392.
10. 32P-labelled nucleoside 3′,5′-bisphosphate adducts of polycyclic aromatic hydrocarbons. J. Chromatogr., 570, 65-76.
11. 32P-postlabeled DNA adducts. Carcinogenesis, 14, 1343-1348.
12. Wohlin, P., Zeisig, M., Gustafsson, J. A. and Möller, L. (1996) 32-P-HPLC analysis of DNA adducts formed in vitro and in vivo by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethyl-3H- imidazo [4,5-f]quinoxaline, utilizing an improved adduct enrichment procedure. Chem. Res. Toxicol., 9, 1050-1056.
13. 32P-postlabeling high-performance liquid chromatographic improvements to characterize DNA adduct stereoisomers from benzo[a]pyrene and benzo[c]phenanthrene, and to separate DNA adducts from 7,12-dimethylbenz[a]anthracene. J. Chromatogr. B Biomed. Sci. Appl., 691, 341-350.
14. 32P-postlabelling assay for cisplatin-DNA adducts. Carcinogenesis, 15, 2829-2834.
15. 32P-HPLC suitable for characterization of DNA adducts formed in vitro by polycyclic aromatic hydrocarbons and derivatives. Carcinogenesis, 16, 1-9.
16. 32P- postlabeling DNA damage assays: PAGE, TLC, and HPLC. Methods Mol. Biol., 314, 307-321.
17. 32P-postlabeling assay for polycyclic aromatic hydrocarbon-DNA adducts. Mutagenesis, 8, 121-126.
18. Nagy, E., Johansson, C., Zeisig, M. and Möller, L. (2005) Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 827, 94-103.
19. Nagy, E., Adachi, S., Takamura-Enya, T., Zeisig, M. and Möller, L. (2007) DNA adduct formation and oxidative stress from the carcinogenic urban air pollutant 3-nitrobenzanthrone and its isomer 2-nitrobenzanthrone, in vitro and in vivo. Mutagenesis, 22, 135-145.
20. 32P-postlabeling assay. Carcinogenesis, 18, 2415-2419.
21. 32P-HPLC) adapted for analysis of 8-hydroxy-2′-deoxyguanosine. Carcinogenesis, 20, 1241-1245.
22. Nagy, E., Noren, U. G., Zeisig, M., Ekstrom, L. G. and Möller, L. (2004) DNA adduct formation and physiological effects from crude oil distillate and its derived base oil in isolated, perfused rat liver. Arch. Toxicol., 78, 114-121.
23. Arlt, V. M., Cole, K. J. and Phillips, D. H. (2004) Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells. Mutagenesis, 19, 149-156.
24. Hofer, T. and Möller, L. (2002) Optimization of the workup procedure for the analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine with electrochemical detection. Chem. Res. Toxicol., 15, 426-432.
25. 32P-postlabeling and ELISA. Carcinogenesis, 15, 557-560.
26. Keith, G. and Dirheimer, G. (1995) Postlabeling: a sensitive method for studying DNA adducts and their role in carcinogenesis. Curr. Opin. Biotechnol., 6, 3-11.
27. 32P-postlabeling/high-performance liquid chromatography method for the analysis of the malondialdehye-derived 1, N2-propanodeoxyguanosine DNA adduct in animal and human tissues. Chem. Res. Toxicol., 11, 1032-1041.