Environmental fate of the antiviral drug Tamiflu in two aquatic ecosystems

Chemosphere

Volumn 75, Issue 1, 2009, Pages 28-33

  Saccà, Maria Ludovica ^a   Accinelli, Cesare ^a   Fick, Jerker ^b   Lindberg, Richard ^b   Olsen, Björn ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UMEÅ UNIVERSITY   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Avian influenza; Bird flu; Oseltamivir; Pharmaceuticals; Surface water

Indexed keywords

ACTIVE METABOLITES; ANTI-VIRAL DRUGS; AQUATIC ECOSYSTEMS; AVIAN INFLUENZA; BIRD FLU; COARSE SEDIMENTS; ENVIRONMENTAL FATES; INCUBATION PERIODS; LABORATORY STUDIES; LIQUID-PHASE; MICROBIAL DEGRADATIONS; NORTHERN ITALY; OSELTAMIVIR; OSELTAMIVIR CARBOXYLATES; PHARMACEUTICALS; PRODRUG; TAMIFLU; VENICE LAGOONS; WATER BODIES; WORLD HEALTH ORGANIZATIONS;

BIOCHEMISTRY; BIODEGRADATION; CARBOXYLATION; DEGRADATION; LAKES; RIVERS; SEDIMENTOLOGY; SEDIMENTS;

BIOLOGICAL MATERIALS;

AQUATIC ECOSYSTEM; DRUG; ENVIRONMENTAL FATE; HALF LIFE; LAGOON; METABOLITE; SEDIMENT POLLUTION; SPATIAL DISTRIBUTION; WATER POLLUTION;

ANTIVIRAL AGENTS; BIODEGRADATION, ENVIRONMENTAL; ECOSYSTEM; ENVIRONMENTAL MONITORING; OSELTAMIVIR; RIVERS; SOIL MICROBIOLOGY; WATER POLLUTANTS, CHEMICAL;

EURASIA; EUROPE; ITALY; PO RIVER; SOUTHERN EUROPE; VENETO; VENEZIA [VENETO]; VENICE LAGOON;

AVES;

EID: 61549119132     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.11.060     Document Type: Article

References (30)

1. Accinelli C., Barra Caracciolo A., and Grenni P. Degradation of the antiviral drug Oseltamivir Carboxylate in surface water samples. Int. J. Environ. Anal. Chem. 87 (2007) 579-587
2. Accinelli C., Hashim M., Epifani R., Schneider R., and Vicari A. Effects of the antimicrobial agent sulfamethazine on metolachlor persistence and sorption in soil. Chemosphere 63 (2006) 1539-1545
3. Bock E., Koops H.P., Ahlers B., and Harms H. The genus Nitrobacter and related genera. In: Balows A., Trüper H.G., Dworkin M., Harder W., and Schleifer K.H. (Eds). The Prokaryotes (1992), Springer-Verlag, New York 414-430
4. Boon N., Top E.M., Verstraete W., and Siciliano S.D. Bioaugmentation as a tool to protect the structure and function of an activated-sludge microbial community against a 3-chloroaniline shock load. Appl. Environ. Microb. 69 (2003) 1511-1520
5. Dionisi H.M., Layton A.C., Harms G., Gregory I.R., Robinson K.G., and Sayler G.S. Quantification of Nitrosomonas oligotropha-like ammonia-oxidizing bacteria and Nitrospira spp. from full-scale wastewater treatment plants by competitive PCR. Appl. Environ. Microb. 68 (2002) 245-253
6. Eisenberg E.J., Bidgood A., and Cundy K.C. Penetration of GS4071, a novel influenza neuramidase inhibitor, into rat bronchoalveolar lining fluid following oral administration of the prodrug GS4104. Antimicrob. Agents Chemoth. 41 (1997) 1942-1949
7. Ferris M.J., Muyzer G., and Ward D.M. Denaturing gradient gel electrophoresis profiles of 16S rRNA-defined populations inhabiting a hot spring microbial mat community. Appl. Environ. Microb. 62 (1996) 340-346
8. Fick J., Lindberg R.H., Tysklind M., Haemig P.D., Waldenström J., Wallensten A., and Olsen B. Antiviral oseltamivir is not removed or degraded in normal sewage water treatment: implications for development of resistance by influenza A virus. PLoS ONE 3 2 10 (2007) e986
9. Griebler C., and Slezak D. Microbial activity in aquatic environments measured by dimethyl sulfoxide reduction and intercomparison with commonly used methods. Appl. Environ. Microb. 67 (2001) 100-109
10. Harms G., Layton A.C., Dionisi H.M., Gregory I.R., Garrett V.M., Hawkins S.A., Robinson K.G., and Sayler G.S. Real-time PCR quantification of nitrifying bacteria in a municipal wastewater treatment plant. Environ. Sci. Technol. 15 (2003) 343-351
11. Hermansson A., and Lindgren PE. Quantification of ammonia-oxidizing bacteria in arable soil by real-time PCR. Appl. Environ. Microb. 67 (2001) 972-976
12. Juliastuti S.R., Baeyens J., and Creemers C. Inhibition of nitrification by heavy metals and organic compounds: the ISO 9509 test. Environ. Eng. Sci. 20 (2003) 79-90
13. Krutz L.J., Senseman S.A., McInnes K.J., Hoffman D.W., and Tierney D.P. Adsorption and desorption of metolachlor and metolachlor metabolites in vegetated filter strip and cultivated soil. J. Environ. Qual. 33 (2004) 939-945
14. Limpiyakorn T., Kurisu F., and Yagi O. Distribution of ammonia-oxidizing bacteria in sewage activated sludge: analysis based on 16S rDNA sequence. Water Sci. Technol. 54 (2004) 9-14
15. Limpiyakorn T., Kurisu F., and Yagi O. Quantification of ammonia-oxidizing bacteria populations in full-scale sewage activated sludge systems and assessment of system variables affecting their performance. Water Sci. Technol. 54 (2006) 91-99
16. Liu B., McConnell L.L., and Torrents A. Hydrolysis of chlorpyrifos in natural waters of the Chesapeake Bay. Chemosphere 44 (2001) 1315-1323
17. Lu J., Wu L., Newman J., Faber B., and Gan J. Degradation of pesticides in nursery recycling pond waters. J. Agr. Food Chem. 54 (2006) 2658-2663
18. Marchesi J.R., Sato T., Weightman A.J., Martin T.A., Fry J.C., Hiom S.J., and Wade W.G. Design and evaluation of useful bacterium-specific PCR primers that amplify genes coding for bacterial 16S rRNA. Appl. Environ. Microb. 64 (1998) 795-799
19. Molina V., Ulloa O., Farías L., Urrutia H., Ramírez S., Junier P., and Witzel K.P. Ammonia-oxidizing β-proteobacteria from the oxygen minimum zone off northern Chile. Appl. Environ. Microb. 73 (2007) 3547-3555
20. Moyer C.L., Dobbs F.C., and Karl D.M. Estimation of diversity and community structure through restriction fragment length polymorphism distribution analysis of bacterial 16S rRNA gene from a microbial mat at an active, hydrothermal vent system, Loihi Seamount, Hawaii. Appl. Environ. Microb. 60 (1994) 871-879
21. Nazaret S., Jeffrey W.H., Saouter E., von Haven R., and Barkay T. MerA gene expression in aquatic environments measured by mRNA production and Hg(II) volatilization. Appl. Environ. Microb. 60 (1994) 4059-4065
22. Oxford J.S., and Lambkin R. Influenza is now a preventable disease. Int. J. Antimicrob. Ag. 27 (2006) 271-273
23. Pagga U., Bachner J., and Strotmann U. Inhibition of nitrification in laboratory tests and model wastewater treatment plants. Chemosphere 65 (2006) 1-8
24. Seybold C.A., and Mersie W. Adsorption and desorption of atrazine, deethylatrazine, deisopropylatrazine, hydroxyatrazine, and metolachlor in two soils from Virginia. J. Environ. Qual. 25 (1996) 1179-1185
25. Singer A.C., Nunn M.A., Gould E.A., and Johnson A.C. Potential risks associated with the widespread use of Tamiflu. Environ. Health Persp. 115 (2007) 102-106
26. ® release to the environment under pandemic conditions. Report from an interdisciplinary workshop. Environ. Health Persp. 116, 1563-1567.
27. Sukul P., Lamshöft M., Zühlke S., and Spiteller M. Sorption and desorption of sulfadiazine in soil and soil-manure systems. Chemosphere 73 (2008) 1344-1350
28. van Benthum W.A.J., van Loosdrecht M.D.M., and Heijnen J.J. Control of heterotrophic layer formation on nitrifying biofilms in a biofilm airlift suspension reactor. Biotechnol. Bioeng. 53 (1997) 397-405
29. Wagner-Döbler I., Pipke R., Timmis K.N., and Dwyer D.F. Evaluation of aquatic sediment microcosms and their use in assessing possible effects of introduced microorganisms on ecosystem parameters. Appl. Environ. Microb. 58 (1992) 1249-1258
30. Ward P., Small I., Smith J., Suter P., and Dutkowski R. Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic. J. Antimicrob. Chemoth. 55 (2005) 5-21