Stereoselective synthesis of (6S) and (6R)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and their cytotoxic activity against cancer cell lines

Tetrahedron

Volumn 65, Issue 15, 2009, Pages 2989-2994

  Narasimhulu, Manchala ^a   Krishna, Arepalli Sai ^a   Rao, Janapala Venkateswara ^a   Venkateswarlu, Yenamandra ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

5,6 Dihydro pyrone; Asymmetric allylation; Cancer cell lines THP 1 and U 937 (leukemia) and A 375 (melanoma); Ravensara crassifolia; Ring closing metathesis

Indexed keywords

5,6 DIHYDRO 6 (2 HYDROXY 6 PHENYLHEXYL) 2H PYRAN 2 ONE; CYTOTOXIC AGENT; LACTONE DERIVATIVE; NATURAL PRODUCT; PYRONE DERIVATIVE; UNCLASSIFIED DRUG;

ALLYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CHIRALITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA; MEDICINAL PLANT; MELANOMA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAVENSARA CRASSIFOLIA; RING CLOSING METATHESIS; STEREOCHEMISTRY;

RAVENSARA;

EID: 61549112213     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2009.01.101     Document Type: Article

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