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Volumn 189, Issue , 2009, Pages 321-346

Antiviral combination therapy for treatment of chronic hepatitis B, hepatitis C, and human immunodeficiency virus infection

Author keywords

[No Author keywords available]

Indexed keywords

4' AZIDOCYTIDINE 2',3',5' TRIISOBUTYRATE; 5 CYCLOPROPYL 2 (4 FLUOROPHENYL) 6 [N (2 HYDROXYETHYL)METHANESULFONAMIDO] N METHYLBENZOFURAN 3 CARBOXAMIDE; A 831; ABACAVIR PLUS LAMIVUDINE PLUS ZIDOVUDINE; ACH 806; ADEFOVIR; ADEFOVIR DIPIVOXIL; ALPHA INTERFERON; AMANTADINE; ANTIRETROVIRUS AGENT; ANTIVIRUS AGENT; BOCEPREVIR; CILUPREVIR; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; DEBIO 25; DIDANOSINE; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; ENTECAVIR; GS 9132; ITMN 191; LAMIVUDINE; NONSTRUCTURAL PROTEIN 5A; PEGINTERFERON ALPHA; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; RIBAVIRIN; TELAPREVIR; TELBIVUDINE; TENOFOVIR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALOPICITABINE; ZIDOVUDINE; INTERFERON;

EID: 61549094730     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-540-79086-0_12     Document Type: Review
Times cited : (14)

References (92)
  • 1
    • 14944364772 scopus 로고    scopus 로고
    • Final phase I/II trial results for NM283, a new polymerase inhibitor for hepatitis C: Antiviral efficacy and tolerance in patients with HCV-1 infection, including previous interferon failures
    • Afdhal N, Godofsky E, Dienstag J, Rustgi V, Schick L, McEniry D, Zhou XJ, Chao G, Fang C, Fielman B, Myers M, Brown N (2004) Final phase I/II trial results for NM283, a new polymerase inhibitor for hepatitis C: antiviral efficacy and tolerance in patients with HCV-1 infection, including previous interferon failures. Hepatology 40 Suppl 1:726
    • (2004) Hepatology , vol.40 , Issue.SUPPL. 1 , pp. 726
    • Afdhal, N.1    Godofsky, E.2    Dienstag, J.3    Rustgi, V.4    Schick, L.5    McEniry, D.6    Zhou, X.J.7    Chao, G.8    Fang, C.9    Fielman, B.10    Myers, M.11    Brown, N.12
  • 3
    • 0037169169 scopus 로고    scopus 로고
    • Different degree of immune recovery using antiretroviral regimens with protease inhibitors or non-nucleosides
    • Barreiro P, Soriano V, Casas E, Gonzalez-Lahoz J (2002) Different degree of immune recovery using antiretroviral regimens with protease inhibitors or non-nucleosides. Aids 16(2):245-249
    • (2002) Aids , vol.16 , Issue.2 , pp. 245-249
    • Barreiro, P.1    Soriano, V.2    Casas, E.3    Gonzalez-Lahoz, J.4
  • 6
    • 0037371144 scopus 로고    scopus 로고
    • Prediction of treatment outcome in patients with chronic hepatitis C: Significance of baseline parameters and viral dynamics during therapy
    • Berg T, Sarrazin C, Herrmann E, Hinrichsen H, Gerlach T, Zachoval R, Wiedenmann B, Hopf U, Zeuzem S (2003) Prediction of treatment outcome in patients with chronic hepatitis C: significance of baseline parameters and viral dynamics during therapy. Hepatology 37(3):600-609
    • (2003) Hepatology , vol.37 , Issue.3 , pp. 600-609
    • Berg, T.1    Sarrazin, C.2    Herrmann, E.3    Hinrichsen, H.4    Gerlach, T.5    Zachoval, R.6    Wiedenmann, B.7    Hopf, U.8    Zeuzem, S.9
  • 9
    • 0028122848 scopus 로고
    • A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C
    • Brillanti S, Garson J, Foli M, Whitby K, Deaville R, Masci C, Miglioli M, Barbara L (1994) A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C. Gastroenterology 107(3):812-817
    • (1994) Gastroenterology , vol.107 , Issue.3 , pp. 812-817
    • Brillanti, S.1    Garson, J.2    Foli, M.3    Whitby, K.4    Deaville, R.5    Masci, C.6    Miglioli, M.7    Barbara, L.8
  • 10
    • 0037333717 scopus 로고    scopus 로고
    • An objective case definition of lipodystrophy in HIV-infected adults: A case-control study
    • PowderlyWG
    • Carr A, Emery S, Law M, Puls R, Lundgren JD, PowderlyWG (2003) An objective case definition of lipodystrophy in HIV-infected adults: a case-control study. Lancet 361(9359):726-735
    • (2003) Lancet , vol.361 , Issue.9359 , pp. 726-735
    • Carr, A.1    Emery, S.2    Law, M.3    Puls, R.4    Lundgren, J.D.5
  • 13
    • 29944436855 scopus 로고    scopus 로고
    • Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • Chen CJ, Yang HI, Su J, Jen CL, You SL, Lu SN, Huang GT, Iloeje UH (2006) Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 295(1):65-73
    • (2006) JAMA , vol.295 , Issue.1 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3    Jen, C.L.4    You, S.L.5    Lu, S.N.6    Huang, G.T.7    Iloeje, U.H.8
  • 14
    • 1442355578 scopus 로고    scopus 로고
    • HIV drug resistance
    • Clavel F, Hance AJ (2004) HIV drug resistance. N Engl J Med 350(10):1023-1035
    • (2004) N Engl J Med , vol.350 , Issue.10 , pp. 1023-1035
    • Clavel, F.1    Hance, A.J.2
  • 16
    • 34848858648 scopus 로고    scopus 로고
    • Four year assessment of ETV resistance in nucleoside-näive and lamivudine refractory patients
    • Colonno R, Rose R, Pokornowski K, Yu C (2007) Four year assessment of ETV resistance in nucleoside-näive and lamivudine refractory patients. J Hepatol 46 Suppl 1:S294
    • (2007) J Hepatol , vol.46 , Issue.SUPPL. 1
    • Colonno, R.1    Rose, R.2    Pokornowski, K.3    Yu, C.4
  • 18
    • 10644264391 scopus 로고    scopus 로고
    • Treatment with pegylated interferon and ribavarin in HCV infection with genotype 2 or 3 for 14 weeks: A pilot study
    • Dalgard O, Bjoro K, Hellum KB, Myrvang B, Ritland S, Skaug K, Raknerud N, Bell H (2004) Treatment with pegylated interferon and ribavarin in HCV infection with genotype 2 or 3 for 14 weeks: a pilot study. Hepatology 40(6):1260-1265
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1260-1265
    • Dalgard, O.1    Bjoro, K.2    Hellum, K.B.3    Myrvang, B.4    Ritland, S.5    Skaug, K.6    Raknerud, N.7    Bell, H.8
  • 19
    • 0041822106 scopus 로고    scopus 로고
    • Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C
    • Davis GL, Wong JB, McHutchison JG, Manns MP, Harvey J, Albrecht J (2003) Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C. Hepatology 38(3):645-652
    • (2003) Hepatology , vol.38 , Issue.3 , pp. 645-652
    • Davis, G.L.1    Wong, J.B.2    McHutchison, J.G.3    Manns, M.P.4    Harvey, J.5    Albrecht, J.6
  • 20
    • 3242877615 scopus 로고    scopus 로고
    • Resistance to HIV protease inhibitors: Mechanisms and clinical consequences
    • de Mendoza C, Soriano V (2004) Resistance to HIV protease inhibitors: Mechanisms and clinical consequences. Curr Drug Metab 5(4):321-328
    • (2004) Curr Drug Metab , vol.5 , Issue.4 , pp. 321-328
    • de Mendoza, C.1    Soriano, V.2
  • 23
    • 33750845765 scopus 로고    scopus 로고
    • Performance of six different ritonavir-boosted protease inhibitor-based regimens in heavily antiretroviral-experienced HIV-infected patients
    • de Mendoza C, Valer L, Ribera E, Barreiro P, Martin-Carbonero L, Ramirez G, Soriano V (2006) Performance of six different ritonavir-boosted protease inhibitor-based regimens in heavily antiretroviral-experienced HIV-infected patients. HIV Clin Trials 7(4):163-171
    • (2006) HIV Clin Trials , vol.7 , Issue.4 , pp. 163-171
    • de Mendoza, C.1    Valer, L.2    Ribera, E.3    Barreiro, P.4    Martin-Carbonero, L.5    Ramirez, G.6    Soriano, V.7
  • 24
    • 34247863946 scopus 로고    scopus 로고
    • Tipranavir: A new protease inhibitor for the treatment of antiretroviral-experienced HIV-infected patients
    • de Mendoza C, Morello J, Garcia-Gasco P, Rodriguez-Novoa S, Soriano V (2007) Tipranavir: A new protease inhibitor for the treatment of antiretroviral-experienced HIV-infected patients. Expert Opin Pharmacother 8(6):839-850
    • (2007) Expert Opin Pharmacother , vol.8 , Issue.6 , pp. 839-850
    • de Mendoza, C.1    Morello, J.2    Garcia-Gasco, P.3    Rodriguez-Novoa, S.4    Soriano, V.5
  • 25
    • 0026733674 scopus 로고    scopus 로고
    • Di Bisceglie AM, Shindo M, Fong TL, FriedMW, SwainMG, Bergasa NV, Axiotis CA,Waggoner JG, Park Y, Hoofnagle JH (1992) A pilot study of ribavirin therapy for chronic hepatitis C. Hepatology 16(3):649-654
    • Di Bisceglie AM, Shindo M, Fong TL, FriedMW, SwainMG, Bergasa NV, Axiotis CA,Waggoner JG, Park Y, Hoofnagle JH (1992) A pilot study of ribavirin therapy for chronic hepatitis C. Hepatology 16(3):649-654
  • 26
    • 0346727453 scopus 로고    scopus 로고
    • Optimized virologic response in hepatitis C virus genotype 4 with peginterferon-alpha2a and ribavirin
    • Diago M, Hassanein T, Rodes J, Ackrill AM, Sedarati F (2004) Optimized virologic response in hepatitis C virus genotype 4 with peginterferon-alpha2a and ribavirin. Ann Intern Med 140(1):72-73
    • (2004) Ann Intern Med , vol.140 , Issue.1 , pp. 72-73
    • Diago, M.1    Hassanein, T.2    Rodes, J.3    Ackrill, A.M.4    Sedarati, F.5
  • 30
    • 7044272630 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in cirrhosis: Incidence and risk factors
    • Fattovich G, Stroffolini T, Zagni I, Donato F (2004). Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology 127(5) Suppl 1:S35-S50
    • (2004) Gastroenterology , vol.127 , Issue.5 SUPPL. 1
    • Fattovich, G.1    Stroffolini, T.2    Zagni, I.3    Donato, F.4
  • 32
    • 4644305114 scopus 로고    scopus 로고
    • Hepatitis B virus genotypes: Do they play a role in the outcome of HBV infection?
    • Fung SK, Lok AS (2004) Hepatitis B virus genotypes: do they play a role in the outcome of HBV infection? Hepatology 40(4):790-792
    • (2004) Hepatology , vol.40 , Issue.4 , pp. 790-792
    • Fung, S.K.1    Lok, A.S.2
  • 35
    • 0033803799 scopus 로고    scopus 로고
    • Efficacy of long-term lamivudine monotherapy in patients with hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Papatheodoridis GV, Dimou E, Laras A, Papaioannou C (2000) Efficacy of long-term lamivudine monotherapy in patients with hepatitis B e antigen-negative chronic hepatitis B. Hepatology 32(4 Pt 1):847-851
    • (2000) Hepatology , vol.32 , Issue.4 PART 1 , pp. 847-851
    • Hadziyannis, S.J.1    Papatheodoridis, G.V.2    Dimou, E.3    Laras, A.4    Papaioannou, C.5
  • 38
    • 77953675231 scopus 로고    scopus 로고
    • Hammer SM, Saag MS, Schechter M, Montaner JS, Schooley RT, Jacobsen DM, Thompson MA, Carpenter CC, Fischl MA, Gazzard BG, Gatell JM, Hirsch MS, Katzenstein DA, Richman DD, Vella S, Yeni Volberding PA (2006) Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. Top HIV Med 14(3):827-843Havlir DV, Richman DD (1996) Viral dynamics of HIV: implications for drug development and therapeutic strategies. Ann Intern Med 124(11):984-994
    • Hammer SM, Saag MS, Schechter M, Montaner JS, Schooley RT, Jacobsen DM, Thompson MA, Carpenter CC, Fischl MA, Gazzard BG, Gatell JM, Hirsch MS, Katzenstein DA, Richman DD, Vella S, Yeni PG, Volberding PA (2006) Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. Top HIV Med 14(3):827-843Havlir DV, Richman DD (1996) Viral dynamics of HIV: implications for drug development and therapeutic strategies. Ann Intern Med 124(11):984-994
  • 41
    • 33845449051 scopus 로고    scopus 로고
    • Peginterferon and ribavirin for chronic hepatitis C
    • Hoofnagle JH, Seeff LB (2006) Peginterferon and ribavirin for chronic hepatitis C. N Engl J Med 355(23):2444-2451
    • (2006) N Engl J Med , vol.355 , Issue.23 , pp. 2444-2451
    • Hoofnagle, J.H.1    Seeff, L.B.2
  • 44
    • 33847676669 scopus 로고    scopus 로고
    • Combination of telaprevir (VX-950) and PEG-IFN-alfa suppresses both wild-type virus and resistance variants in HCV genotype 1-infected patients in a 14-day phase 1b study
    • Kieffer T, Sarrazin C,Miller J, Traver S, Zhou Y, Bartels D, Hanzelka B, Muh U, Lin C, Reesink H, Kwong A, Zeuzem S (2006) Combination of telaprevir (VX-950) and PEG-IFN-alfa suppresses both wild-type virus and resistance variants in HCV genotype 1-infected patients in a 14-day phase 1b study. Hepatology 44(4):222A-223A
    • (2006) Hepatology , vol.44 , Issue.4
    • Kieffer, T.1    Sarrazin, C.2    Miller, J.3    Traver, S.4    Zhou, Y.5    Bartels, D.6    Hanzelka, B.7    Muh, U.8    Lin, C.9    Reesink, H.10    Kwong, A.11    Zeuzem, S.12
  • 49
    • 32444438958 scopus 로고    scopus 로고
    • Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine
    • Lampertico P, Vigano M, Manenti E, Iavarone M, Lunghi G, Colombo M (2005) Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine. Hepatology 42(6):1414-1419
    • (2005) Hepatology , vol.42 , Issue.6 , pp. 1414-1419
    • Lampertico, P.1    Vigano, M.2    Manenti, E.3    Iavarone, M.4    Lunghi, G.5    Colombo, M.6
  • 52
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • Lavanchy D (2004) Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 11(2):97-107
    • (2004) J Viral Hepat , vol.11 , Issue.2 , pp. 97-107
    • Lavanchy, D.1
  • 56
    • 12844279849 scopus 로고    scopus 로고
    • High-dose ribavirin in combination with standard dose peginterferon for treatment of patients with chronic hepatitis C
    • Lindahl K, Stahle L, Bruchfeld A, Schvarcz R (2005) High-dose ribavirin in combination with standard dose peginterferon for treatment of patients with chronic hepatitis C. Hepatology 41(2):275-279
    • (2005) Hepatology , vol.41 , Issue.2 , pp. 275-279
    • Lindahl, K.1    Stahle, L.2    Bruchfeld, A.3    Schvarcz, R.4
  • 57
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • Lok AS, McMahon BJ (2007) Chronic hepatitis B. Hepatology 45(2):507-539
    • (2007) Hepatology , vol.45 , Issue.2 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 58
    • 0142214798 scopus 로고    scopus 로고
    • Significance of hepatitis B viremia levels determined by a quantitative polymerase chain reaction assay in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection
    • Manesis EK, Papatheodoridis GV, Sevastianos V, Cholongitas E, Papaioannou C, Hadziyannis SJ (2003) Significance of hepatitis B viremia levels determined by a quantitative polymerase chain reaction assay in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection. Am J Gastroenterol 98(10):2261-2267
    • (2003) Am J Gastroenterol , vol.98 , Issue.10 , pp. 2261-2267
    • Manesis, E.K.1    Papatheodoridis, G.V.2    Sevastianos, V.3    Cholongitas, E.4    Papaioannou, C.5    Hadziyannis, S.J.6
  • 61
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, Goodman ZD, Koury K, Ling M, Albrecht JK (2001) Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358(9286):958-965
    • (2001) Lancet , vol.358 , Issue.9286 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3    Rustgi, V.K.4    Shiffman, M.5    Reindollar, R.6    Goodman, Z.D.7    Koury, K.8    Ling, M.9    Albrecht, J.K.10
  • 65
    • 33646882606 scopus 로고    scopus 로고
    • Review article: Predicting response in hepatitis C virus therapy
    • Mihm U, Herrmann E, Sarrazin C, Zeuzem S (2006) Review article: predicting response in hepatitis C virus therapy. Aliment Pharmacol Ther 23(8):1043-1054
    • (2006) Aliment Pharmacol Ther , vol.23 , Issue.8 , pp. 1043-1054
    • Mihm, U.1    Herrmann, E.2    Sarrazin, C.3    Zeuzem, S.4
  • 66
    • 14644402363 scopus 로고    scopus 로고
    • Current and future concepts in hepatitis C therapy
    • Pawlotsky JM (2005) Current and future concepts in hepatitis C therapy. Semin Liver Dis 25(1):72-83
    • (2005) Semin Liver Dis , vol.25 , Issue.1 , pp. 72-83
    • Pawlotsky, J.M.1
  • 68
    • 33745440781 scopus 로고    scopus 로고
    • HIV tropism: Diagnostic tools and implications for disease progression and treatment with entry inhibitors
    • Poveda E, Briz V, Quinones-Mateu M, Soriano V (2006). HIV tropism: diagnostic tools and implications for disease progression and treatment with entry inhibitors. Aids 20(10):1359-1367
    • (2006) Aids , vol.20 , Issue.10 , pp. 1359-1367
    • Poveda, E.1    Briz, V.2    Quinones-Mateu, M.3    Soriano, V.4
  • 69
    • 0032585237 scopus 로고    scopus 로고
    • Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT)
    • Poynard T, Marcellin P, Lee SS, Niederau C, Minuk GS, Ideo G, Bain V, Heathcote J, Zeuzem S, Trepo C, Albrecht J (1998) Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet 352(9138):1426-1432
    • (1998) Lancet , vol.352 , Issue.9138 , pp. 1426-1432
    • Poynard, T.1    Marcellin, P.2    Lee, S.S.3    Niederau, C.4    Minuk, G.S.5    Ideo, G.6    Bain, V.7    Heathcote, J.8    Zeuzem, S.9    Trepo, C.10    Albrecht, J.11
  • 70
    • 77953681103 scopus 로고    scopus 로고
    • Reesink HW, Zeuzem S, Weegink CJ, Forestier N, van Vliet A, van de Wetering de Rooij J, McNair L, Purdy S, Chu HM, Jansen PLM (2005) Final results of a phase 1b multiple dose study of VX950, a hepatitis C virus protease inhibitor. Hepatology 42(1):234AReiser M, Hinrichsen H, Benhamou Y, Reesink HW, Wedemeyer H, Avendano C, Riba N, Yong CL, Nehmiz G, Steinmann GG (2005) Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C. Hepatology 41(4):832-835
    • Reesink HW, Zeuzem S, Weegink CJ, Forestier N, van Vliet A, van de Wetering de Rooij J, McNair L, Purdy S, Chu HM, Jansen PLM (2005) Final results of a phase 1b multiple dose study of VX950, a hepatitis C virus protease inhibitor. Hepatology 42(1):234AReiser M, Hinrichsen H, Benhamou Y, Reesink HW, Wedemeyer H, Avendano C, Riba N, Yong CL, Nehmiz G, Steinmann GG (2005) Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C. Hepatology 41(4):832-835
  • 73
    • 77953654720 scopus 로고    scopus 로고
    • Sarrazin C, Kieffer T, Bartels D, Hanzelka B, MÅ h U, Welker M, Wincheringer D, Lin C, Grossmann T, Purdy S, Weegink C, Reesink H, Zeuzem S, Kwong A (2005) Characterization of viral variants in the HCV NS3 protease domain of genotype 1 patients that are selected during 14 days of dosing with VX-950. Hepatology 42(1):751A
    • Sarrazin C, Kieffer T, Bartels D, Hanzelka B, MÅ h U, Welker M, Wincheringer D, Lin C, Grossmann T, Purdy S, Weegink C, Reesink H, Zeuzem S, Kwong A (2005) Characterization of viral variants in the HCV NS3 protease domain of genotype 1 patients that are selected during 14 days of dosing with VX-950. Hepatology 42(1):751A
  • 75
    • 0034861494 scopus 로고    scopus 로고
    • Sequential treatment with lamivudine and interferon monotherapies in patients with chronic hepatitis B not responding to interferon alone: Results of a pilot study
    • Serfaty L, Thabut D, Zoulim F, Andreani T, Chazouilleres O, Carbonell N, Loria A, Poupon R (2001) Sequential treatment with lamivudine and interferon monotherapies in patients with chronic hepatitis B not responding to interferon alone: results of a pilot study. Hepatology 34(3):573-577
    • (2001) Hepatology , vol.34 , Issue.3 , pp. 573-577
    • Serfaty, L.1    Thabut, D.2    Zoulim, F.3    Andreani, T.4    Chazouilleres, O.5    Carbonell, N.6    Loria, A.7    Poupon, R.8
  • 77
    • 0015523596 scopus 로고    scopus 로고
    • Sidwell RW, Huffman JH, Khare GP, Allen LB,Witkowski JT, Robins RK (1972) Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4- triazole-3-carboxamide. Science 177(50):705-706
    • Sidwell RW, Huffman JH, Khare GP, Allen LB,Witkowski JT, Robins RK (1972) Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4- triazole-3-carboxamide. Science 177(50):705-706
  • 78
    • 0142034717 scopus 로고    scopus 로고
    • A randomised double-blind phase II study of lamivudine (LAM) compared to lamivudine plus adefovir dipivoxil (ADV) for treatment naive patients with chronic hepatitis B (CHB): Week 52 analysis
    • Sung JJY, Lai JY, Zeuzem S, Chow WC, Heathcote E, Perrillo R, Brosgart C, Woessner M, Scott SA, Campbell FM (2003) A randomised double-blind phase II study of lamivudine (LAM) compared to lamivudine plus adefovir dipivoxil (ADV) for treatment naive patients with chronic hepatitis B (CHB): Week 52 analysis. J Hepatol 38:25-26
    • (2003) J Hepatol , vol.38 , pp. 25-26
    • Sung, J.J.Y.1    Lai, J.Y.2    Zeuzem, S.3    Chow, W.C.4    Heathcote, E.5    Perrillo, R.6    Brosgart, C.7    Woessner, M.8    Scott, S.A.9    Campbell, F.M.10
  • 79
    • 0033012793 scopus 로고    scopus 로고
    • Efficacy of lamivudine in patients with hepatitis B e antigennegative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Lamivudine Precore Mutant Study Group
    • Tassopoulos NC, Volpes R, Pastore G, Heathcote J, Buti M, Goldin RD, Hawley S, Barber J, Condreay L, Gray DF (1999) Efficacy of lamivudine in patients with hepatitis B e antigennegative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Lamivudine Precore Mutant Study Group. Hepatology 29(3):889-896
    • (1999) Hepatology , vol.29 , Issue.3 , pp. 889-896
    • Tassopoulos, N.C.1    Volpes, R.2    Pastore, G.3    Heathcote, J.4    Buti, M.5    Goldin, R.D.6    Hawley, S.7    Barber, J.8    Condreay, L.9    Gray, D.F.10
  • 80
    • 33646036163 scopus 로고    scopus 로고
    • Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034
    • Tong X, Chase R, Skelton A, Chen T, Wright-Minogue J, Malcolm BA (2006) Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034. Antiviral Res 70(2):28-38
    • (2006) Antiviral Res , vol.70 , Issue.2 , pp. 28-38
    • Tong, X.1    Chase, R.2    Skelton, A.3    Chen, T.4    Wright-Minogue, J.5    Malcolm, B.A.6
  • 83
    • 33846521154 scopus 로고    scopus 로고
    • Viral determinants of resistance to treatment in patients with hepatitis C
    • Wohnsland A, Hofmann WP, Sarrazin C (2007) Viral determinants of resistance to treatment in patients with hepatitis C. Clin Microbiol Rev 20(1):23-38
    • (2007) Clin Microbiol Rev , vol.20 , Issue.1 , pp. 23-38
    • Wohnsland, A.1    Hofmann, W.P.2    Sarrazin, C.3
  • 85
    • 24944488875 scopus 로고    scopus 로고
    • Response to combined interferon and ribavirin is better in patients infected with hepatitis C virus genotype 6 than genotype 1 in Hong Kong
    • Yuen MF, Lai CL (2006) Response to combined interferon and ribavirin is better in patients infected with hepatitis C virus genotype 6 than genotype 1 in Hong Kong. Intervirology 49(1-2):96-98
    • (2006) Intervirology , vol.49 , Issue.1-2 , pp. 96-98
    • Yuen, M.F.1    Lai, C.L.2
  • 86
    • 33846053592 scopus 로고    scopus 로고
    • Combination therapy for chronic hepatitis B: Simultaneous or sequential?
    • Yuen MF, Lai CL (2007) Combination therapy for chronic hepatitis B: Simultaneous or sequential? Am J Gastroenterol 102(1):105-106
    • (2007) Am J Gastroenterol , vol.102 , Issue.1 , pp. 105-106
    • Yuen, M.F.1    Lai, C.L.2
  • 89
    • 21844477610 scopus 로고    scopus 로고
    • Zeuzem S, Pawlotsky JM, Lukasiewicz E, vonWagner M, Goulis I, Lurie Y, Gianfranco E, Vrolijk JM, Esteban JI, Hezode C, Lagging M, Negro F, Soulier A, Verheij-Hart E, Hansen B, Tal R, Ferrari C, Schalm SW, Neumann AU (2005a) International, multicenter, randomized, controlled study comparing dynamically individualized versus standard treatment in patients with chronic hepatitis C. J Hepatol 43(2):250-257
    • Zeuzem S, Pawlotsky JM, Lukasiewicz E, vonWagner M, Goulis I, Lurie Y, Gianfranco E, Vrolijk JM, Esteban JI, Hezode C, Lagging M, Negro F, Soulier A, Verheij-Hart E, Hansen B, Tal R, Ferrari C, Schalm SW, Neumann AU (2005a) International, multicenter, randomized, controlled study comparing dynamically individualized versus standard treatment in patients with chronic hepatitis C. J Hepatol 43(2):250-257
  • 90
    • 30344485556 scopus 로고    scopus 로고
    • Anti-viral activity of SCH503034, a HCV protease inhibitor, administered as monotherapy in hepatitis C genotype-1 (HCV-1) patients refractory to pegylated interferon (PEG-IFNalfa)
    • Zeuzem S, Sarrazin C, Rouzier R, Tarral A, Brion N, Forestier N, Gupta S, Deckman D, Fellows K, Hussain M, Cutler DL, Zhang J (2005b) Anti-viral activity of SCH503034, a HCV protease inhibitor, administered as monotherapy in hepatitis C genotype-1 (HCV-1) patients refractory to pegylated interferon (PEG-IFNalfa). Hepatology 42(1):233A
    • (2005) Hepatology , vol.42 , Issue.1
    • Zeuzem, S.1    Sarrazin, C.2    Rouzier, R.3    Tarral, A.4    Brion, N.5    Forestier, N.6    Gupta, S.7    Deckman, D.8    Fellows, K.9    Hussain, M.10    Cutler, D.L.11    Zhang, J.12
  • 91
    • 28844451934 scopus 로고    scopus 로고
    • Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia
    • Zeuzem S, Buti M, Ferenci P, Sperl J, Horsmans Y, Cianciara J, Ibranyi E, Weiland O, Noviello S, Brass C, Albrecht J (2006) Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia. J Hepatol 44(1):97-103
    • (2006) J Hepatol , vol.44 , Issue.1 , pp. 97-103
    • Zeuzem, S.1    Buti, M.2    Ferenci, P.3    Sperl, J.4    Horsmans, Y.5    Cianciara, J.6    Ibranyi, E.7    Weiland, O.8    Noviello, S.9    Brass, C.10    Albrecht, J.11
  • 92
    • 33747119322 scopus 로고    scopus 로고
    • Antiviral therapy of chronic hepatitis B
    • Zoulim F (2006) Antiviral therapy of chronic hepatitis B. Antiviral Res 71(2-3):206-215
    • (2006) Antiviral Res , vol.71 , Issue.2-3 , pp. 206-215
    • Zoulim, F.1


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